Molecular Mechanisms of Membrane Fusion

Front Matter....Pages i-ix
Calcium-Induced Membrane Fusion: From Liposomes to Cellular Membranes....Pages 1-16
Gel Phase Fusion of Dipalmitoyl Phosphatidylcholine Small Unilamellar Vesicles....Pages 17-24
Structural Characterization of Lamellar Mg 2+ Complexes of Dilauroylphosphatidic Acid Using 31 P and 13 NMR....Pages 25-36
Lipid Polymorphism, Lipid Asymmetry and Membrane Fusion....Pages 37-51
Membrane Fusion via Intermediates in L α /H II Phase Transitions....Pages 53-71
The Influence of Polar Group Identity on the Interactions between Phospholipid Bilayers....Pages 73-81
Intrinsic Colloidal Attraction/Repulsion between Lipid Bilayers and Strong Attraction Induced by Non-adsorbing Polymers....Pages 83-99
Mechanisms of Membrane Fusion in Acidic Lipid-Cation Systems....Pages 101-112
Polar Interfacial Interactions, Hydration Pressure and Membrane Fusion....Pages 113-122
Surface Tension, Hydration Energy and Membrane Fusion....Pages 123-138
Interactions in Liposomal-Drug Delivery in Vivo and in Vitro....Pages 139-148
Drug Delivery by Immunoliposomes....Pages 149-161
Osmotic Forces and the Fusion of Biomembranes....Pages 163-179
Fusion in Biological and Model Membranes: Similarities and Differences....Pages 181-195
Early Steps in the Exocytosis of Secretory Vesicles in Mast Cells....Pages 197-208
Electrofusion and Electrotransfection of Cells....Pages 209-222
Pre-selection of B-Lymphocytes by Antigen for Fusion to Myeloma Cells by Pulsed Electric Field (PEF) Method....Pages 223-236
The Mechanism of Erythrocyte Ghost Fusion by Electric Field Pulses....Pages 237-254
Water-Mediated Effects of PEG on Membrane Properties and Fusion....Pages 255-272
Control of Cell Membrane Fusion by Lipid Composition....Pages 273-288
Role of Phospholipid Asymmetry in Cellular Membrane Fusion....Pages 289-301
Ultrastructural Studies of the Kinetics of Fusion....Pages 303-316
pH Triggered Synthetic Peptides: Models for Viral Fusion Sequences....Pages 317-324
Membrane Fusion in Model Systems for Exocytosis: Characterization of Chromaffin Granule Fusion Mediated by Synexin and Calelectrin....Pages 325-340
Synexin, Calcium and the Hydrophobic Bridge Hypothesis for Membrane Fusion....Pages 341-355
Molecular Mechanism of Protein-Mediated Low ph-Induced Membrane Fusions....Pages 357-366
pH-Dependent Fusion of Vesicular Stomatitis Virus with Cells: Studies of Mechanism Based on an Allosteric Model....Pages 367-383
Properties of a Viral Fusion Protein....Pages 385-398
Parameters Affecting the Fusion of Viruses with Artificial and Biological Membranes....Pages 399-412
Active Function of Membrane Receptors in Fusion of Enveloped Viruses with Cell Plasma Membranes....Pages 413-426
‘Entry’ of Enveloped Viruses into Liposomes....Pages 427-440
Fusion Activity of Influenza Virus and Reconstituted Viral Envelopes: Direct Evidence for Fusion in an Intracellular Acidic Compartment....Pages 441-450
Kinetics and Extent of Fusion of Influenza Virus and Sendai Virus with Liposomes....Pages 451-465
Strategies for the Investigation of Exocytotic Membrane Fusion....Pages 467-476
Enzymatic Regulation of Membrane Fusion During Synchronous Exocytosis in Paramecium Cells....Pages 477-494
Studies on the Structure and Function of the Asialoglycoprotein Receptor in the Cell, in Vitro, and in Reconstituted Membranes....Pages 495-512
Phosphorylation Events in Regulation of Exocytosis....Pages 513-520
Geometric Topology of Membrane Fusion: From Secretion to Intercellular Junctions....Pages 521-530
‘Slow Artifacts’ in Assays of Lipid Mixing between Membranes....Pages 531-542
Why Fusion Assays Disagree....Pages 543-555
Concentration Dependence of DPHpPC Fluorescence Lifetime: Photophysics and Utility for Monitoring Membrane Fusion....Pages 557-566
Back Matter....Pages 567-588