Molecular Mechanisms of Alcohol: Neurobiology and Metabolism

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Specific Action of Ethanol on Lateral and Vertical Membrane Lipid Domains....Pages 3-13
Effects of Acute and Chronic Ethanol Administration on Metabolism of Brain Acidic Phospholipids....Pages 15-38
Effects of Ethanol on Receptors Coupled to Phosphoinositide Hydrolysis in Brain....Pages 39-55
The Effects of Ethanol on Synaptic Membrane Calcium Transporting Systems....Pages 57-67
Depolarization-Dependent Poly-Phosphoinositide Hydrolysis in Brain is Inhibited by Ethanol In Vitro ....Pages 69-74
Glutamic Acid Synaptic Activity is a Target of Acute and Chronic Ethanol Effects in the Mammalian Brain....Pages 75-86
Effect of Ethanol Administration on the Phosphorylation of a 43KDa Synaptosomal Protein....Pages 87-95
Ethanol Alters Monoamine Content in Different Brain Regions of Spontaneously Hypertensive Rats....Pages 97-105
Synthesis of Fatty Acid Ethyl Esters by Brain Membranes....Pages 107-118
Vasopressin and Ethanol Tolerance: Postulated Mechanism for Neuroadaptation....Pages 119-131
Serotonergic Mechanisms in Alcohol Intake....Pages 133-146
Mechanisms of Central Nervous System Alcohol-Related Birth Defects....Pages 147-165
Front Matter....Pages 167-167
Prenatal Ethanol Studies on Astrocytes....Pages 169-192
Cell Cultures as a Model for Alcohol Research....Pages 193-205
Ethanol and Bradykinin-Stimulated Phosphoinositide Hydrolysis in NG108–15 Neuroblastoma-Glioma Cells....Pages 207-214
Effect of Lipid Peroxidation on Glucose Transport in Astrocytes: Potentiation by Ethanol....Pages 215-224
Front Matter....Pages 225-225
Genetic Polymorphism and Properties of Human Alcohol and Aldehyde Dehydrogenases: Implications for Ethanol Metabolism and Toxicity....Pages 227-247
Population Differences in ALDH Levels and Flushing Response....Pages 249-255
Spin Trapping Studies of the Influence of Alcohol on Lipid Peroxidation....Pages 257-277
Comparative Study on Biochemical Effects of Alcohols on Rat Liver Mitochondrial Respiration and Oxidative Phosphorylation....Pages 279-292
Front Matter....Pages 225-225
Increases in Hepatic Gammaglutamyl Transferase Following Alcohol Consumption. A Hepatoprotective Rather Than a Pathogenic Role....Pages 293-304
Effects of Chronic Ethanol and Fish Oil on Plasma and Liver Lipids and Plasma Apoproteins....Pages 305-316
Effects of Ethanol on Contractility and Membrane Currents of Cardiac Tissue....Pages 317-326
Effect of Acute Ethanol on Membrane Transport of Folate....Pages 327-334
Alcoholism: A Low-Risk Risorder for Chinese? Community Surveys in Taiwan....Pages 335-355
Front Matter....Pages 357-357
Mechanism(s) of Modulation of Alcohol Consumption: Studies on the P and NP Rats....Pages 359-370
Miniature Swine as an Animal Model for Alcohol Research....Pages 371-388
Back Matter....Pages 389-397