Molecular Insights into Ion Channel Biology in Health and Disease

Content: 
Contents
Pages v-vi

Preface
Pages vii-ix

ATP-sensitive potassium channels and insulin secretion diseases Review Article
Pages 1-14
C.G. Nichols, S.-L. Shyng, B. Marshall, J.C. Koster

The biology of voltage-gatedsodium channels Review Article
Pages 15-50
John H Caldwell, S.Rock Levinson

Towards a natural history of calcium-activated potassium channels Review Article
Pages 51-71
David P. McCobb

Cystic fibrosis transmembrane conductance regulator Review Article
Pages 73-94
J.W Hanrahan

Molecular insights into acetylcholine receptor structure and function revealed by mutations causing congenital myasthenic syndromes Review Article
Pages 95-119
Steven M. Sine, Andrew G. Engel, Hai-Long Wang, Kinji Ohno

Store-operated calcium channels: properties, functions and the search for a molecular mechanism Review Article
Pages 121-140
Murali Prakriya, Richard S. Lewis

Neurodegenerative disease and the neuroimmunobiology of glutamate receptors Review Article
Pages 141-159
Lorise C. Gahring, Noel G. Carlson, Erin L. Meyer, Emily L. Days, Scott W. Rogers

Gap junction mutations in human disease Review Article
Pages 161-187
Matthew G Hopperstad, Miduturu Srinivas, Alfredo Fort, David C Spray

Molecular physiology and pathophysiology of ClC-type chloride channels Review Article
Pages 189-217
Christoph Fahlke

Steroid modulation of GABAA receptors:from molecular mechanisms to CNS roles in reproduction, dysfunction and drug abuse Review Article
Pages 219-250
Leslie P. Henderson, Juan Carlos Jorge

Cyclic nucleotide-gated channels: multiple isoforms, multiple roles Review Article
Pages 251-267
Marie-Christine Broillet, Stuart Firestein

Nicotinic acetylcholine receptors in the nervous system Review Article
Pages 269-302
Joseph P Margiotta, Phyllis C Pugh

The ENaC/Deg family of cation channels Review Article
Pages 303-329
Sylvie Coscoy, Pascal Barbry

Vanilloid receptor 1 (VR1): an integrator of noxious and inflammatory stimuli∗ Review Article
Pages 331-350
Stuart Bevan, Alison J Reeve

Novel roles for aquaporins as gated ion channels Review Article
Pages 351-379
Andrea J. Yool, W.Daniel Stamer

Molecular and functional insights into voltage-gated calcium channels Review Article
Pages 381-406
Anthony Stea, Terrance P. Snutch

Ion channels and sperm function Review Article
Pages 407-431
Ricardo Felix, Ignacio López-González, Carlos Muñoz-Garay, Alberto Darszon

Ion channels on intracellular organelles Review Article
Pages 433-458
Leonard K. Kaczmarek, Elizabeth A. Jonas

Colour plates
Pages 459-469

Contributors
Pages 471-475

Index
Pages 477-785