Molecular genetics of mycobacteria

 Content: GENOMES, GENOMICS, AND GENETIC EXCHANGE 1. Gene Transfer in Mycobacterium tuberculosis: Shuttle Phasmids to Enlightenment, William R. Jacobs, Jr. 2. Mycobacterial Pathogenomics and Evolution, Daria Bottai, Timothy P. Stinear, Philip Supply, and Roland Brosch 3. BCG Vaccines, Vanessa Tran, Jun Liu, and Marcel A. Behr 4. Distributive Conjugal Transfer: New Insights into Horizontal Gene Transfer and Genetic Exchange in Mycobacteria, Keith M. Derbyshire and Todd A. Gray 5. Molecular Genetics of Mycobacteriophages, Graham F. Hatfull 6. Genetics of Phage Lysis, Madalena Pimentel   GENE EXPRESSION AND REGULATION 7. Sigma Factors: Key Molecules in Mycobacterium tuberculosis Physiology and Virulence, Riccardo Manganelli 8. Transcription Factor Binding Site Mapping Using ChIP-Seq, Suma Jaini, Anna Lyubetskaya, Antonio Gomes, Matthew Peterson, Sang Tae Park, Sahadevan Raman, Gary Schoolnik, and James Galagan  9. Noncoding RNA in Mycobacteria, Kristine B. Arnvig, Teresa Cortes, and Douglas B. Young 10.Two-Component Regulatory Systems of Mycobacteria, Tanya Parish 11.Regulated Expression Systems for Mycobacteria and Their Applications, Dirk Schnappinger and Sabine Ehrt   THE MYCOBACTERIAL PROTEOME 12.Mycobacterium tuberculosis in the Proteomics Era, Martin Gengenbacher, Jeppe Mouritsen, Olga T. Schubert, Ruedi Aebersold, and Stefan H. E. Kaufmann 13.Structural Annotation of the Mycobacterium tuberculosis Proteome, Nagasuma Chandra, Sandhya Sankaran, and Praveen Anand 14.Cyclic AMP Signaling in Mycobacteria, Gwendowlyn S. Knapp and Kathleen A. McDonough   METABOLISM 15.The Physiology and Genetics of Oxidative Stress in Mycobacteria, Bridgette M. Cumming, Dirk Lamprecht, Ryan M. Wells, Vikram Saini, James H. Mazorodze, and Adrie J. C. Steyn 16.Metabolomics of Central Carbon Metabolism in Mycobacterium tuberculosis, Anthony D. Baughn and Kyu Y. Rhee 17.Mycobacterial Lipidomics, Emilie Layre, Reem Al-Mubarak, John T. Belisle, and D. Branch Moody 18.Genetics of Mycobacterial Trehalose Metabolism, Rainer Kalscheuer and Hendrik Koliwer-Brandl 19.Metallobiology of Tuberculosis, G. Marcela Rodriguez and Olivier Neyrolles 20.Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria, Gregory M. Cook, Kiel Hards, Catherine Vilcheze, Travis Hartman, and Michael Berney   GENETICS OF DRUG RESISTANCE 21.Molecular Basis of Drug Resistance in Mycobacterium tuberculosis, Keira A. Cohen, William R. Bishai, and Alexander S. Pym 22.Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities, Catherine Vilcheze and William R. Jacobs, Jr. 23.The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis, Claudine Mayer and Howard Takiff 24.Mechanisms of Pyrazinamide Action and Resistance, Ying Zhang, Wanliang Shi, Wenhong Zhang, and Denis Mitchison 25.Genetic Strategies for Identifying New Drug Targets, Andrej Trauner, Christopher M. Sassetti, and Eric J. Rubin   GENETICS OF MEMBRANE AND CELL WALL BIOSYNTHESIS 26.Genetics of Peptidoglycan Biosynthesis, Martin S. Pavelka, Jr., Sebabrata Mahapatra, and Dean C. Crick 27.Genetics of Mycobacterial Arabinogalactan and Lipoarabinomannan Assembly, Monika Jankute, Shipra Grover, Helen L. Birch, and Gurdyal S. Besra 28.Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids, Mamadou Daffe, Dean C. Crick, and Mary Jackson 29.The Molecular Genetics of Mycolic Acid Biosynthesis, Jakub Pawelczyk and Laurent Kremer   GENETICS OF MACROMOLECULAR BIOSYNTHESIS 30.Nucleotide Metabolism and DNA Replication, Digby F. Warner, Joanna C. Evans, and Valerie Mizrahi 31.Double-Strand DNA Break Repair in Mycobacteria, Michael S. Glickman 32.The Pup-Proteasome System of Mycobacteria, Nadine J. Bode and K. Heran Darwin 33.Mycobacterium tuberculosis Serine/Threonine Protein Kinases, Sladjana Prisic and Robert N. Husson   THE MYCOBACTERIAL LIFESTYLE, PERSISTENCE, AND MACROPHAGE SURVIVAL 34.The Spectrum of Drug Susceptibility in Mycobacteria, Bree B. Aldridge, Iris Keren, and Sarah M. Fortune 35.The Sculpting of the Mycobacterium tuberculosis Genome by Host Cell-Derived Pressures, David G. Russell, Wonsik Lee, Shumin Tan, Neelima Sukumar, Maria Podinovskaia, Ruth J. Fahey, and Brian C. VanderVen  36.Evasion of Innate and Adaptive Immunity by Mycobacterium tuberculosis, Michael F. Goldberg, Neeraj K. Saini, and Steven A. Porcelli 37.Mycobacterial Biofilms, Jacobs P. Richards and Anil K. Ojha
 Abstract:             
              A comprehensive collection of perspectives by experts in mycobacterial molecular biology, written by leading experts in the field. This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.                 Read more...