Molecular Diagnostics and Treatment of Pancreatic Cancer. Systems and Network Biology Approaches

Content: 
Front Matter, Page iii
Copyright, Page iv
Dedication, Page v
Preface, Pages xiii-xiv
Acknowledgments, Page xv
Contributors, Pages xvii-xx
Chapter 1 - Epidemiology, Treatment, and Outcome of Pancreatic Cancer, Pages 3-9
Chapter 2 - Advances in Primary Cell Culture of Pancreatic Cancer, Pages 11-38
Chapter 3 - Multimodal Therapies for Pancreatic Cancer, Pages 39-73
Chapter 4 - The Role of Notch Signaling Pathway in the Progression of Pancreatic Cancer, Pages 75-89
Chapter 5 - Bioinformatics Analysis of Pancreas Cancer Genome in High-Throughput Genomic Technologies, Pages 93-131
Chapter 6 - Statistical Analysis of High-Dimensional Data for Pancreatic Cancer, Pages 133-150
Chapter 7 - Gene Expression Profiling in Pancreatic Cancer, Pages 151-167
Chapter 8 - Genetic Susceptibility and Risk of Pancreatic Cancer, Pages 169-194
Chapter 9 - Proteomics in Pancreatic Cancer Translational Research, Pages 197-219
Chapter 10 - Proteomic Differences and Linkages between Chemoresistance and Metastasis of Pancreatic Cancer Using Knowledge-Based Pathway Analysis, Pages 221-244
Chapter 11 - RNAi Validation of Pancreatic Cancer Antigens Identified by Cell Surface Proteomics, Pages 245-277
Chapter 12 - The Significance of the Feedback Loops between Kras and Ink4a in Pancreatic Cancer, Pages 281-296
Chapter 13 - Systems Biology of Pancreatic Cancer Stem Cells, Pages 297-322
Chapter 14 - Characterizing the Metabolomic Effects of Pancreatic Cancer, Pages 323-343
Chapter 15 - Prioritizing Diagnostic, Prognostic, and Therapeutic MicroRNAs in Pancreatic Cancer: Systems and Network Biology Approaches, Pages 345-363
Chapter 16 - Integration of Protein Network Activation Mapping Technology for Personalized Therapy: Implications for Pancreatic Cancer, Pages 367-383
Chapter 17 - Computational and Biological Evaluation of Radioiodinated Quinazolinone Prodrug for Targeting Pancreatic Cancer, Pages 385-403
Chapter 18 - Systems and Network Pharmacology Strategies for Pancreatic Ductal Adenocarcinoma Therapy: A Resource Review, Pages 405-425
Index, Pages 427-446