Molecular Diagnostics, Second Edition

Content: 
Copyright, Page iv
Contributors, Pages ix-xii, Farid E. Ahmed, Claus L. Andersen, Wilhelm J. Ansorge, Aglaia Athanassiadou, Francisco E. Baralle, Matthew P.G. Barnett, Sina Bavari, Alex van Belkum, Walter Bell, Fernando Benavides, Karin Birkenkamp-Demtroder, Lauryn Blakesley, Anja Katrin Bosserhoff, Bruce Budowle, Chinh Thien Bui, David Burnett, Rowan S. Campbell, Timothy Caulfield, Maria Chiotis, Tim Conze,  et al.
Preface – First Edition, Pages xiii-xiv, George P. Patrinos, Wilhelm J. Ansorge
Preface – Second Edition, Pages xv-xvi, George P. Patrinos, Wilhelm J. Ansorge
Foreword – First Edition, Page xvii, Fotis C. Kafatos
Chapter 1 - Molecular Diagnostics: Past, Present, and Future, Pages 1-11, George P. Patrinos, Wilhelm J. Ansorge
Chapter 2 - Allele-Specific Mutation Detection, Pages 15-28, Aglaia Athanassiadou, Eleana F. Stavrou, Adamandia Papachatzopoulou, George P. Patrinos
Chapter 3 - Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation, Pages 29-44, Chinh T. Bui, Emmanuelle Nicolas, Georgina Sallmann, Maria Chiotis, Andreana Lambrinakos, Kylee Rees, Ian Trounce, Richard G.H. Cotton, Lauryn Blakesley, Andrew K. Godwin, Anthony T. Yeung
Chapter 4 - Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis, Pages 45-58, Panayiotis G. Menounos, George P. Patrinos
Chapter 5 - Capillary Electrophoresis, Pages 59-73, Anja Bosserhoff, Claus Hellerbrand
Chapter 6 - Temperature and Denaturing Gradient Gel Electrophoresis, Pages 75-86, Hartmut Peters, Peter N. Robinson
Chapter 7 - Real-Time Polymerase Chain Reaction, Pages 87-105, Lut Overbergh, Anna-Paula Giulietti, Dirk Valckx, Chantal Mathieu
Chapter 8 - Pyrosequencing, Pages 107-116, Sharon Marsh
Chapter 9 - Application of Padlock and Selector Probes in Molecular Medicine, Pages 117-132, Mats Nilsson, Chatarina Larsson, Johan Stenberg, Jenny Göransson, Ida Grundberg, Magnus Isaksson, Tim Conze, Sara Henriksson
Chapter 10 - Molecular Cytogenetics in Molecular Diagnostics, Pages 133-153, Holger Tönnies
Chapter 11 - Analysis of Human Splicing Defects Using Hybrid Minigenes, Pages 155-169, Franco Pagani, Francisco E. Baralle
Chapter 12 - Detection of Genomic Duplications and Deletions, Pages 171-182, Graham R. Taylor, Carol A. Delaney
Chapter 13 - Multiplex Ligation-Dependent Probe Amplification (MLPA) and Methylation-Specific (MS)-MLPA: Multiplex Detection of DNA/mRNA Copy Number and Methylation Changes, Pages 183-198, Eline M. Sepers, Jan P. Schouten
Chapter 14 - Molecular Techniques for DNA Methylation Studies, Pages 199-228, Jörg Tost, Ivo G. Gut
Chapter 15 - High-Resolution Melting Curve Analysis for Molecular Diagnostics, Pages 229-245, Jared S. Farrar, Gudrun H. Reed, Carl T. Wittwer
Chapter 16 - DNA Microarrays and Genetic Testing, Pages 247-265, Lars Dyrskjøt, Karina Dalsgaard-Sørensen, Marie Stampe-Ostenfeld, Karin Birkenkamp-Demtroder, Kasper Thorsen, Claus L. Andersen, Mogens Kruhøffer, Jens L. Jensen, Torben F. Ørntoft
Chapter 17 - Arrayed Primer Extension Microarrays for Molecular Diagnostics, Pages 267-284, Neeme Tonisson, Eneli Oitmaa, Kaarel Krjutskov, Janne Pullat, Ilona Lind, Merike Leego, Ants Kurg, Andres Metspalu
Chapter 18 - Application of Proteomics to Disease Diagnostics, Pages 285-291, Samir Hanash, Ji Qiu, Vitor Faca
Chapter 19 - RNA-Based Variant Detection: The Protein Truncation Test, Pages 293-298, Johan T. den Dunnen
Chapter 20 - Protein Diagnostics by Proximity Ligation: Combining Multiple Recognition and DNA Amplification for Improved Protein Analyses, Pages 299-306, Karl-Johan Leuchowius, Ola Söderberg, Masood Kamali-Moghaddam, Malin Jarvius, Irene Weibrecht, Katerina Pardali, Ulf Landegren
Chapter 21 - Mass Spectrometry and its Applications to Functional Proteomics, Pages 307-323, Thomas Köcher, Giulio Superti-Furga
Chapter 22 - Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Clinical Care, Pages 325,327-345, Minoli Perera, Federico Innocenti
Chapter 23 - Nutrigenomics: Integrating Genomic Approaches into Nutrition Research, Pages 347-363, Lynette R. Ferguson, Martin Philpott, Matthew P.G. Barnett
Chapter 24 - Novel Next-Generation DNA Sequencing Techniques for Ultra High-Throughput Applications in Bio-Medicine, Pages 365-378, Wilhelm J. Ansorge
Chapter 25 - Locus-Specific and National/Ethnic Mutation Databases: Emerging Tools for Molecular Diagnostics, Pages 379-391, George P. Patrinos
Chapter 26 - Molecular Diagnostic Applications in Forensic Science, Pages 393-406, Bruce Budowle, John V. Planz, Rowan Campbell, Arthur J. Eisenberg
Chapter 27 - Mass Disaster Victim Identification Assisted by DNA Typing, Pages 407-415, Daniel Corach
Chapter 28 - Detection of Highly Pathogenic Viral Agents: Implications for Therapeutics, Vaccines and Biodefense, Pages 417-429, Kylene Kehn-Hall, Sina Bavari
Chapter 29 - Identification of Genetically Modified Organisms, Pages 431-444, Farid E. Ahmed
Chapter 30 - Molecular Diagnostics and Comparative Genomics in Clinical Microbiology, Pages 445-460, Alex van Belkum
Chapter 31 - Genetic Monitoring of Laboratory Rodents, Pages 461-469, Jean-Louis Guénet, Fernando J. Benavides
Chapter 32 - Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells, Pages 471-484, Stephanie Laufs, Luisa Schubert, Patrick Maier, W. Jens Zeller, Stefan Fruehauf
Chapter 33 - Preimplantation Genetic Diagnosis, Pages 485-500, Martine de Rycke, Karen Sermon
Chapter 34 - Automated DNA Hybridization and Detection, Pages 501-511, Bert Gold
Chapter 35 - The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays, Pages 513-526, Piotr Grodzinski, Michael Ward, Robin Liu, Kathryn Scott, Saul Surrey, Paolo Fortina
Chapter 36 - Human Gene Patents and Genetic Testing, Pages 527-536, Timothy Caulfield, Yann Joly
Chapter 37 - Genetic Counseling and Ethics in Molecular Diagnostics, Pages 537-548, Mary Petrou
Chapter 38 - Genetic Testing and Psychology, Pages 549-562, Andrea Farkas Patenaude
Chapter 39 - General Considerations Concerning Safety in Biomedical Research Laboratories, Pages 563-572, William E. Grizzle, Walter C. Bell, Jerry Fredenburgh
Chapter 40 - Quality Management in the Laboratory, Pages 573-581, David Burnett
Glossary, Pages 583-589
Index, Pages 591-598