Molecular Biology of Hematopoiesis 5

Front Matter....Pages i-xvii
T-Cells, Graft-Versus-Host Disease, and Graft-Versus-Leukemia....Pages 1-10
Combined Use of Growth Factors to Stimulate the Proliferation of Hematopoietic Progenitor Cells after Autologous Bone Marrow Transplantation (ABMT) for Lymphoma Patients....Pages 11-20
Long-Term Multilineage Development from Human Umbilical Cord Blood Stem Cells in a Novel SCID-HU Graft....Pages 21-30
Peripheral Blood Stem Cells Mobilization with G-CSF (FILGRASTIM) Alone for Autologous Transplant in Myeloid and Lymphoid Malignancies....Pages 31-35
Density Separation and Cryopreservation of Umbilical Cord Blood Cells....Pages 37-43
Economic Implications of High Dose Chemotherapy Programs with Autologous Stem Cell Support....Pages 45-52
CFU-GM Growth from Peripheral Blood Stem Cells (PBSC) Before and After Cryopreservation....Pages 53-57
Is there an Embryological Basis for the Association of Mediastinal Germ Cell Tumors and Hematologic Cancers?....Pages 59-68
Autologous BMT for Treatment of Experimental Autoimmune Diseases....Pages 69-76
Peripheral Blood Precursor Cell Transplants Across a Major Histocompatibility Barrier in Rabbits....Pages 77-82
Reticulocyte Parameters as Early Indicators of Hematopoietic Recovery after Bone marrow Transplantation....Pages 83-91
Primordial Germ Cell-Derived Hemopoiesis....Pages 93-99
Monitoring of Serum HLA Class I Antigen Levels in Allogeneic Bone Marrow Transplantation....Pages 101-105
Correlation of Elisa-Measured anti-HLA Class I IGG and IGG1 Antibodies and First-Year Rejection Episodes....Pages 107-113
Inactivation or Down-Regulation of the Overstimulated, HLA-DR-(CD2R-, CD26-, CD38-, and/or CD69-) Positive T Cell Subset Enables the Immunocompetent Cells to Restore the Pre-Disease State....Pages 115-122
European Cup Trial....Pages 123-126
Mechanisms of Chromosomal Translocations in Malignant Lymphomas....Pages 127-134
Molecular Findings and Classification of Malignant Lymphomas....Pages 135-144
Mantle Cell Lymphoma....Pages 145-150
Lymphoblastic Lymphoma In Adults....Pages 151-157
A New Non-Radioactive Method For Detection of Monoclonal Cell Populations in Patients With Burkitt’s Lymphoma....Pages 159-167
Oncogenes in the Pathogenesis of Multiple Myeloma....Pages 169-172
Expression and Regulation of c-kit Receptor and Proliferative Response to Stem Cell Factor in Childhood Lymphoma and Leukemia Cells....Pages 173-189
Growth Inhibition in IL-7 Receptor Positive Childhood Burkitt’s Lymphoma Cells is not due to Induction of Apoptosis....Pages 191-200
Expression of the Multidrug-Resistance Gene Product, P-Glycoprotein, In Adult Acute Myeloid Leukemia....Pages 201-206
Characterization of N-RAS Promoter Mutations In Leukemia....Pages 207-213
The Role of Anthracycline S in the Management of Adult Acute Lymphoblastic Leukaemia....Pages 215-219
Collection of bcr/abl Negative Peripheral Blood Progenitor Cells in Newly Diagnosed Patients with Chronic Myeloid Leukaemia....Pages 221-226
CD34 Quantitative Flow Cytometry Study of the Blastic Population in Acute Leukemias....Pages 227-235
Cytokine Gene Expression in a Case of B-Cell Chronic Lymphocytic Leukemia (B-CLL) With an Unusual Expansion of T Cells at Presentation....Pages 237-246
Exploitation Of Frequent p16 Deletion In The Treatment Of T Cell Acute Lymphoblastic Leukemia....Pages 247-256
Detection of bcr-abl m-RNA in Single Progenitor Colonies by PCR....Pages 257-267
Quantitative RT-PCR of PML-RARα Transcripts in Acute Promyelocytic Leukemia....Pages 269-276
Aids-Related Non-Hodgkin Lymphomas....Pages 277-284
Anti-Hiv Viral Interference Induced by Retroviral Vectors Expressing a Non-Producer Hiv-1 Variant....Pages 285-291
Suppression of Hematopoietic Support Function is Associated with over-Expression of IL-4 and TGFβ1 in LP-BM5 MuLV Infected Stromal Cell Lines....Pages 293-305
Role of HIV-1 in the Functional Impairment of CD34 + Hematopoietic Progenitor Cells....Pages 307-312
Humoral Immune Response to Human Cytomegalovirus....Pages 313-322
Targeted Gene Transfer into CD4 Positive Cells by HIV-Based Retroviral Vectors....Pages 323-329
In Vitro Retroviral Vector-Mediated Transfer of the Rat Beta-Glucuronidase cDNA into Canine Fetal Liver Cells and Weanling MPS VII Bone Marrow Cells....Pages 331-337
The Simulation of Hematopoiesis....Pages 339-344
Homologous Gene Targeting For Human Gene Therapy....Pages 345-349
Transfection of the Human Heme Oxygenase Gene into Rabbit Coronary Microvessel Endothelial Cells....Pages 351-360
Expression and Signal Transduction of the FLT3 Tyrosine Kinase Receptor....Pages 361-367
JAK2 is Constitutively Associated with C-Kit and is Phosphorylated in Response to Stem Cell Factor....Pages 369-376
Erythroid-Specific Activation of the Distal (TESTIS) Promoter of GATA1 During Differentiation of Purified Normal Murine Hematopoietic Stem Cells....Pages 377-385
Proto-Oncogene Products Vav and c-Cbl are Involved in the Signal Transduction Through Grb2/Ash in Hematopoietic Cells....Pages 387-396
IL3BP1, A Transcription Factor with Dual Function....Pages 397-402
Adhesion of Human Hematopoietic Progenitor Cells to Stromal Cells is Enhanced by Antibodies to CD44....Pages 403-409
Fas and FasL Interactions in Cytotoxicity and its Role in Lymphoproliferative Disease....Pages 411-416
Antisense Oligonucleotides to mdr1 Increase Adriamycin Susceptibility in Breast Cancer Cell Lines....Pages 417-430
Transcriptional Activation of the Human Heme Oxygenase-1 Gene during Acute-Phase Reaction....Pages 431-438
Transcriptional Control of the Human Heme Oxygenase-1 Gene by Stress....Pages 439-444
Megakaryocyte Growth and Maturation from Purified Peripheral Blood Progenitors in Unilineage Serum-Free Liquid Culture....Pages 445-452
Roles of JAK2 in Human GM-CSF Receptor Signals....Pages 453-462
Neural Regulation of Hematopoiesis by the Tachykinins....Pages 463-470
Historical Aspects of Physiological Cell Death Prior to Description of Apoptosis....Pages 471-475
Thrombopoietin....Pages 477-483
Biologic Effects of Thrombopoietin (TPO)....Pages 485-491
Antisense Oligonucleotides to Both Human and Murine Acetylcholinesterase Promote Myeloid Stem Cell Expansion and Reduce Erythroid and Megakaryocyte Lineages in Murine CFU-GEMM....Pages 493-500
Gata Transcription Factors Negatively Regulate Erythropoietin Gene Expression....Pages 501-513
The Ribosomal S6 Kinase P70 S6k Is Involved in the Regulation of The Proliferation Of Hematopoietic Cell Lines But Not In The Induction Of Erythroid Differentiation By Erythropoietin....Pages 515-521
Role of Hydrogen Peroxide in Hypoxia-Induced Expression of the Erythropoietin and the Vascular Endothelial Growth Factor Genes....Pages 523-530
Redox and Heat Shock Protein Hsp70 Affect the Binding of Erythropoietin RNA Binding Protein to Erythropoietin mRNA....Pages 531-540
The Role of Hemopoietic Cytokines in the Myelodysplastic Syndromes....Pages 541-547
Stem Cell Factor as a Survival and Growth Factor in Human Normal and Malignant Hematopoiesis....Pages 549-558
The Role of GM-CSF in Chronic Infections....Pages 559-563
Dysregulation of Cytokine Gene Expression as a Cause of T Cell Transformation and In Vivo Tumorigenicity....Pages 565-570
The Myeloproliferative Disorders and their Treatment with Interferon Alfa....Pages 571-576
Inhibition of Hematopoiesis by in Vivo Activated T Cells Secreting High Amounts of Interferon-γ (IFN-γ) Plus Interleukin 10 (IL-10)....Pages 577-586
Role of Nitric Oxide in the Actions of Cytokines on Hypothalamic Releasing Hormone Secretion....Pages 587-591
Neuroendocrine Control of the Thymus....Pages 593-599
Developmental and Evolutionary Aspects of Thymic T Cell Education to Neuroendocrine Self....Pages 601-608
Hematopoietic Rescue Via αl-Adrenoceptors on Bone Marrow B Cell Precursors and Endogenous Transforming Growth Factor-β....Pages 609-617
Melatonin-Induced Hematopoietic-Neuroendocrine Cytokines....Pages 619-626
Innervation of Bone Marrow by Tyrosine Hydroxylase-Immunoreactive Nerve Fibers and Hemopoiesis-Modulating Activity of a β-Adrenergic Agonist in Mouse....Pages 627-636
IL-1, IL-6, and TNF-α Release is Downregulated in Whole Blood from Septic Patients....Pages 637-644
Expression of Transforming Growth Factor-Beta Type II Receptors in the Cells of the Human Thymic Microenvironment During Ontogenesis....Pages 645-658
New Directions in Iron Chelating Therapy....Pages 659-666
Molecular Pathogenesis of Hemochromatosis....Pages 667-670
Antimalarial Action of Iron Chelators....Pages 671-676
Inhibition of Reperfusion Injury by Iron Chelators....Pages 677-683
Clinical Studies of Iron-Chelating Treatment in Malaria....Pages 685-691
Iron Regulation of Transferrin Receptor and Ferritin Expression in Differentiating Friend Leukemia Cells....Pages 693-703
Lactoferrin....Pages 705-714
Back Matter....Pages 713-715