Modern Magnetic Resonance

Front Matter....Pages 1-9
NMR Diffusometry....Pages 109-115
Field Gradient NMR of Liquid Crystals....Pages 117-122
Field Gradient NMR for Polymer Systems with Cavities....Pages 123-127
NMR Measurements Using Field Gradients and Spatial Information....Pages 129-134
Theory and Application of NMR Diffusion Studies....Pages 135-143
Solid-State NMR in Host-Guest Chemistry....Pages 147-154
Mapping of Flow and Acceleration with NMR Microscopy Techniques....Pages 157-162
Industrial Application of In situ NMR Imaging Experiments to Steel-Making Process....Pages 163-171
Kinetics of Amyloid Fibril Formation of Human Calcitonin....Pages 11-17
Polymorphism of Alzheimer’s Aβ Amyloid Fibrils....Pages 19-27
 13 C, 15 N, 1 H, 2 H, and 17 O NMR Chemical Shift NMR for Hydrogen Bonds....Pages 31-35
NMR Chemical Shift Map....Pages 37-42
NMR Chemical Shifts Based on Band Theory....Pages 43-52
Modeling NMR Chemical Shifts....Pages 53-62
 Ab Initio Calculation of NMR Shielding Constants....Pages 63-70
Crystal Structure Refinement Using Chemical Shifts....Pages 71-78
The Theory of Nuclear Spin-Spin Couplings....Pages 79-83
Investigation of Collagen Dynamics by Solid-State NMR Spectroscopy....Pages 87-92
Solid-State NMR Studies of Elastin and Elastin Peptides....Pages 93-99
Structural Analysis of Silk Fibroins using NMR....Pages 101-106
Front Matter....Pages 1-9
Recent Developments in Stable-Isotope-Aided Methods for Protein NMR Spectroscopy....Pages 215-222
Structural Glycobiology by Stable-isotope-assisted NMR Spectroscopy....Pages 223-229
Site-Directed NMR Studies on Membrane Proteins....Pages 291-297
Structure of Membrane-Binding Proteins Revealed by Solid-State NMR....Pages 299-303
Solid-State NMR of Membrane-Active Proteins and Peptides....Pages 305-311
Magnetic Resonance Spectroscopic Studies of the Integral Membrane Protein Phospholamban....Pages 313-318
NMR Studies of the Interactions Between Ligands and Membrane-Embedded Receptors: New Methods for Drug Discovery....Pages 319-326
Photosynthetic Antennae and Reaction Centers....Pages 327-333
Development and Application of Bicelles for Use in Biological NMR and Other Biophysical Studies....Pages 233-239
Nuclear Magnetic Resonance of Oriented Bilayer Systems....Pages 241-247
Solid-State Deuterium NMR Spectroscopy of Membranes....Pages 249-260
Solid State 19 F-NMR Analysis of Oriented Biomembranes....Pages 261-267
Solid-State NMR Studies of the Interactions and Structure of Antimicrobial Peptides in Model Membranes....Pages 271-278
Anisotropie Chemical Shift Perturbation Induced by Ions in Conducting Channels....Pages 279-283
NMR Studies of Ion-Transporting Biological Channels....Pages 285-288
Biomedical NMR Spectroscopy and Imaging....Pages 173-178
Electron Spin Resonance Imaging in Polymer Research....Pages 179-185
NMR Imaging: Monitoring of Swelling of Environmental Sensitive Hydrogels....Pages 187-193
Exploiting 1 H→ 29 Si Cross-Polarization Features for Structural Characterization of Inorganic Materials....Pages 197-203
Solid State NMR Characterization of Solid Surface of Heterogeneous Catalysts....Pages 205-211
Front Matter....Pages 1-9
Fast Multidimensional NMR: New Ways to Explore Evolution Space....Pages 347-352
High-Sensitivity NMR Probe Systems....Pages 353-361
Cramps....Pages 363-371
Mobile NMR....Pages 373-382
Rheo-NMR....Pages 383-388
Analytical Aspects of Solid-State NMR Spectroscopy....Pages 389-394
 3 H NMR and Its Application....Pages 395-398
On-line SEC-NMR....Pages 399-405
Organoboron Chemistry....Pages 455-457
Organogermanium Chemistry....Pages 459-460
Organotin Chemistry....Pages 461-463
Insight into Membrane Protein Structure from High-Resolution NMR....Pages 335-343
The Nuclear Overhauser Effect....Pages 409-412
Solute-Solvent Interactions Examined by the Nuclear Overhauser Effect....Pages 413-420
Chemical Exchange....Pages 421-427
 1 H and 13 C High-Resolution Solid-State NMR of Paramagnetic Compounds Under Very Fast Magic Angle Spinning....Pages 467-474
Paramagnetic Effects of Dioxygen in Solution NMR—Studies of Membrane Immersion Depth, Protein Topology, and Protein Interactions....Pages 475-483
Separated Detection of H-Transfer Motions in Multi-H-Bonded Systems Studied by Combined 1 H NMR and 35 Cl NQR Measurements....Pages 431-438
EPR: Principles....Pages 439-444
Zero Field NMR: NMR and NQR in Zero Magnetic Field....Pages 445-451
Front Matter....Pages 1-9
TROSY NMR for Studies of Large Biological Macromolecules in Solution....Pages 487-496
NMR Insight of Structural Stability and Folding of Calcium-Binding Lysozyme....Pages 497-501
NMR Investigation of Calmodulin....Pages 503-516
Analytical Framework for Protein Structure Determination by Solid-State NMR of Aligned Samples....Pages 517-526
Determining Protein 3D Structure by Magic Angle Spinning NMR....Pages 527-530
 19 F NMR Study of b -Type Haemoproteins....Pages 531-538
NMR in Dry or Swollen Temporary or Permanent Networks....Pages 541-543
Crystalline Structure of Ethylene Copolymers and Its Relation to the Comonomer Content....Pages 545-549
Isomorphism in Bacterially Synthesized Biodegradable Copolyesters....Pages 551-555
Two-Dimensional NMR Analysis of Stereoregularity of Polymers....Pages 557-562
Quantitative Analysis of Conformations in Disordered Polymers by Solid-State Multiple-Quantum NMR....Pages 563-566
Polymer Microstructure: The Conformational Connection to NMR....Pages 567-574
Solid-State NMR Characterization of Polymer Interfaces....Pages 575-581
The Structure of Polymer Networks....Pages 583-589
 1 H CRAMPS NMR of Polypeptides in the Solid State....Pages 591-604
Dynamics of Amorphous Polymers....Pages 607-613
Molecular Motions of Crystalline Polymers by Solid-State MAS NMR....Pages 615-619
Dynamics in Polypeptides by Solid State 2 H NMR....Pages 621-627
Polymer Blends....Pages 631-635
Configurational Entropy and Polymer Miscibility: New Experimental Insights From Solid-State NMR....Pages 637-644
Front Matter....Pages 1-9
Analytical and Numerical Tools for Experiment Design in Solid-State NMR Spectroscopy....Pages 679-687
Homonuclear Shift-Correlation Experiment in Solids....Pages 689-693
Two-Dimensional 17 O Multiple-Quantum Magic-Angle Spinning NMR of Organic Solids....Pages 695-701
A Family of PISEMA Experiments for Structural Studies of Biological Solids....Pages 703-709
New Applications for Residual Dipolar Couplings: Extending the Range of NMR in Structural Biology....Pages 657-664
Refinement of Nucleic Acid Structures with Residual Dipolar Coupling Restraints in Cartesian Coordinate Space....Pages 665-670
Conformational Analysis of DNA and RNA....Pages 671-676
Rotational-Echo, Double-Resonance NMR....Pages 713-718
REDOR in Multiple Spin System....Pages 719-725
Torsion Angle Determination by Solid-State NMR....Pages 727-733
Secondary Structure Analysis of Proteins from Angle-Dependent Interactions....Pages 735-740
Quantum Information Processing as Studied by Molecule-Based Pulsed ENDOR Spectroscopy....Pages 647-654
Comparison of DNA-Binding Activities Between hTRF2 and hTRFl with hTRF2 Mutants....Pages 743-751
Optimization of MRI Contrast for Pre-Clinical Studies at High Magnetic Field....Pages 759-768
The Application of In Vivo MRI and MRS in Phenomic Studies of Murine Models of Disease....Pages 769-785
Experimental Models of Brain Disease: MRI Contrast Mechanisms for the Assessment of Pathophysio logical Status....Pages 787-799
Experimental Models of Brain Disease: MRI Studies....Pages 801-821
Application of MRS in Cancer in Pre-clinical Models....Pages 823-833
Experimental Cardiovascular MR in Small Animals....Pages 835-853
Application of Pharmacological MRI to Preclinical Drug Discovery and Development....Pages 855-877
Application of MRI to Cell Tracking....Pages 879-890
Comprehensive Compositional Analysis of Fish Feed by Time Domain NMR....Pages 897-903
Low Field NMR Studies of Atlantic Salmon (Salmo salar) ....Pages 905-913
Water Distribution and Mobility in Fish Products in Relation to Quality....Pages 915-918
Proton NMR of Fish Oils and Lipids....Pages 919-923
Determination of Fatty Acid Composition and Oxidation in Fish Oils by High Resolution Nuclear Magnetic Resonance Spectroscopy....Pages 925-931
Resonance Spectroscopy to Study Lipid Oxidation in Fish and Fish Products....Pages 933-940
Omega-3 Fatty Add Content of Intact Muscle of Farmed Atlantic Salmon (Salmo salar) Examined by 1 H MAS NMR Spectroscopy....Pages 941-945
HR MAS NMR Spectroscopy of Marine Microalgae, Part 1: Classification and Metabolite Composition from HR MAS 1 H NMR Spectra and Multivariate Analysis....Pages 947-951
HR MAS NMR Spectroscopy of Marine Microalgae, Part 2: 13 C and 13 C HR MAS NMR Analysis Used to Study Fatty Add Composition and Polysaccharide Structure....Pages 953-957
Post-mortem Studies of Fish Using Magnetic Resonance Imaging....Pages 959-966
How is the Fish Meat Affected by Technological Processes?....Pages 967-971
Front Matter....Pages 973-983
Acquiring Neurospectroscopy in Clinical Practice....Pages 985-1003
Application of Magnetic Resonance for the Diagnosis of Infective Brain Lesions....Pages 1005-1013
Application of 2D Magnetic Resonance Spectroscopy to the Study of Human Biopsies....Pages 1015-1025
Correlation of Histopathology with Magnetic Resonance Spectroscopy of Human Biopsies....Pages 1027-1036
Functional MRI....Pages 1037-1050
High Resolution Magic Angle Spinning (HRMAS) Proton MRS of Surgical Specimens....Pages 1051-1064
Intraoperative MRI....Pages 1065-1076
 In Vivo Magnetic Resonance Spectroscopy in Breast Cancer....Pages 1077-1086
Front Matter....Pages 973-983
 In Vivo Molecular MR Imaging: Potential and Limits....Pages 1087-1098
 In vivo 13 C MRS....Pages 1099-1112
Magnetic Resonance Spectroscopy and Spectroscopic Imaging of the Prostate, Breast, and Liver....Pages 1113-1125
MR-Mammography....Pages 1127-1141
Phosphorus Magnetic Resonance Spectroscopy on Biopsy and In Vivo ....Pages 1143-1161
Radio Frequency Coils for Magnetic Resonance Spectroscopy....Pages 1163-1170
Spatially Resolved Two-Dimensional MR Spectroscopy in vivo ....Pages 1171-1183
Front Matter....Pages 1185-1193
Overview of NMR in the Pharmaceutical Sciences....Pages 1195-1202
Applications of Cryogenic NMR Probe Technology for the Identification of Low-Level Impurities in Pharmaceuticals....Pages 1205-1212
Flow NMR Techniques in the Pharmaceutical Sciences....Pages 1213-1219
Developments in NMR Hyphenation for Pharmaceutical Industry....Pages 1221-1228
LC-NMR in Dereplication and Structure Elucidation of Herbal Drugs....Pages 1229-1235
New Approaches to NMR Data Acquisition, Assignment and Protein Structure Determination: Potential Impact in Drug Discovery....Pages 1239-1246
Transferred Cross-Correlated Relaxation: Application to Drug/Target Complexes....Pages 1247-1254
Novel Uses of Paramagnets to Solve Complex Protein Structures....Pages 1255-1261
Fast Assignments of 15 N-HSQC Spectra of Proteins by Paramagnetic Labeling....Pages 1263-1269
Phospholipid Bicelle Membrane Systems for Studying Drug Molecules....Pages 1271-1277
Partial Alignment for Structure Determination of Organic Molecules....Pages 1279-1285
Measurement of Residual Dipolar Couplings and Applications in Protein NMR....Pages 1287-1291
Using Chemical Shift Perturbations to Validate and Refine the Docking of Novel IgE Antagonists to the High-Affinity IgE Receptor....Pages 1293-1298
Front Matter....Pages 1185-1193
Dual-Region Hadamard-Encoding to Improve Resolution and Save Time....Pages 1299-1304
Nonuniform Sampling in Biomolecular NMR....Pages 1305-1311
Structural Characterization of Antimicrobial Peptides by NMR Spectroscopy....Pages 1315-1323
Pharmaceutical Applications of Ion Channel Blockers: Use of NMR to Determine the Structure of Scorpion Toxins....Pages 1325-1330
Structure and Dynamics of Inhibitor and Metal Binding to Metallo-ß-Lactamases....Pages 1331-1337
NMR Spectroscopy in the Analysis of Protein-Protein Interactions....Pages 1339-1346
Identification and Characterization of Ternary Complexes Using NMR Spectroscopy....Pages 1347-1356
The Transferred NOE....Pages 1357-1362
NMR Kinetic Measurements in DNA Folding and Drug Binding....Pages 1363-1367
The Use of NMR in the Studies of Highly Flexible States of Proteins: Relation to Protein Function and Stability....Pages 1369-1376
NMR-based Metabonomics Techniques and Applications....Pages 1377-1385
Protein Misfolding Disease: Overview of Liquid and Solid-State High Resolution NMR Studies....Pages 1387-1391
 19 F NMR Spectroscopy for Functional and Binding High-Throughput Screening....Pages 1393-1399
Applications of Receptor-Based NMR Screening in Drug Discovery....Pages 1401-1407
NMR SHAPES Screening....Pages 1409-1417
NMR-Based Screening Applied to Drug Discovery Targets....Pages 1419-1428
NMR and Structural Genomics in the Pharmaceutical Sciences....Pages 1429-1434
Front Matter....Pages 1435-1438
Acoustically Stimulated NMR Relaxometry: Application to the Study of Molecular Dynamics in Liquid Crystalline Materials....Pages 1439-1444
Characterization of Elastomers Based on Monitoring Ultraslow Dipolar Correlations by NMR....Pages 1445-1453
Correlating Molecular and Macroscopic Properties of Elastomers by NMR Relaxometry and Multi-pulse NMR Techniques....Pages 1455-1461
Front Matter....Pages 1435-1438
Determining Structural and Dynamic Distribution Functions from Inhomogeneously Broadened NMR Spectra: The Conjugate Orthogonal Functions Approach....Pages 1463-1469
Fluid Diffusion in Partially Filled Nanoscopic and Microscopic Porous Materials....Pages 1471-1477
Gas Adsorption on Carbon Nanotubes....Pages 1479-1485
Magnetic Resonance Studies of the Heterogeneous Rotational and Translational dynamics in Disordered Materials....Pages 1487-1492
Nuclear Magnetic Resonance in Ferromagnetic Multilayers and Nanocomposites: Investigations of Their Structural and Magnetic Properties....Pages 1493-1498
 1 H Solid-State NMR of Supramolecular Systems....Pages 1499-1506
Quadrupolar NMR of Inorganic Materials: The Multiple-Quantum Magic Angle Spinning Experiment....Pages 1507-1514
Rheo-NMR Spectroscopy....Pages 1515-1521
Advances in Single-Sided NMR....Pages 1523-1527
Site-specific Characterization of Structure and Dynamics of Complex Materials by EPR Spin Probes....Pages 1529-1537
NMR of Organic Semiconductors....Pages 1539-1545
Solid State NMR of Xerogels....Pages 1547-1550
Solid-State 17 O NMR Spectroscopy of High-Pressure Silicates....Pages 1551-1561
The Structure of Oxide Glasses: Insights from 17 O NMR....Pages 1563-1568
Studies of the Local Structure of Silk Using Solid-State NMR....Pages 1569-1579
Velocity Imaging of Granular Materials....Pages 1581-1587
Front Matter....Pages 1589-1595
Characterization of the Chemical Composition of Beverages by NMR Spectroscopy....Pages 1597-1603
High Resolution NMR of Carrageenans....Pages 1605-1610
Flavor-Food Compound Interactions by NMR Spectroscopy....Pages 1611-1615
High-Resolution Nuclear Magnetic Resonance Spectroscopy of Fruit Juices....Pages 1617-1621
Front Matter....Pages 1589-1595
High-Resolution NMR Spectroscopy in Human Metabolism and Metabonomics....Pages 1623-1630
High-Resolution NMR of Milk and Milk Proteins....Pages 1631-1635
High-Resolution 13 C Nuclear Magnetic Resonance in the Study of Oils....Pages 1637-1643
High-Resolution 1 H Nuclear Magnetic Resonance in the Study of Oils....Pages 1645-1650
SNIF-NMR—Part 1: Principles....Pages 1651-1658
SNIF-NMR—Part 2: Isotope Ratios as Tracers of Chemical and Biochemical Mechanistic Pathways....Pages 1659-1667
SNIF-NMR—Part 3: From Mechanistic Affiliation to Origin Inference....Pages 1669-1680
SNIF-NMR—Part 4: Applications in an Economic Context: The Example of Wines, Spirits, and Juices....Pages 1681-1687
High-Resolution Nuclear Magnetic Resonance Spectroscopy of Wine, Beer, and Spirits....Pages 1689-1694
NMR Relaxation of Dairy Products....Pages 1697-1701
Characterization of Molecular Mobility in Carbohydrate Food Systems by NMR....Pages 1703-1712
Diffusion and Relaxation in Gels....Pages 1713-1719
NMR Relaxation and Diffusion Studies of Horticultural Products....Pages 1721-1727
Proton NMR Relaxometry in Meat Science....Pages 1729-1733
Time-Domain NMR in Quality Control: More Advanced Methods....Pages 1735-1738
Time-Domain NMR in Quality Control: Standard Applications in Food....Pages 1739-1743
Nuclear Magnetic Relaxation in Starch Systems....Pages 1745-1754
Magic Angle Spinning NMR of Flours and Doughs....Pages 1757-1763
High-Resolution Magic Angle Spinning NMR Spectroscopy of Fruits and Vegetables....Pages 1765-1768
High-Resolution Solid-State NMR of Gluten and Dough....Pages 1769-1776
Front Matter....Pages 1589-1595
ESR as a Technique for Food Irradiation Detection....Pages 1855-1860
ESR Spectroscopy for the Study of Oxidative Processes in Food and Beverages....Pages 1861-1866
Chemornetric Analysis of NMR Data....Pages 1833-1843
Direct Exponential Curve Resolution by Slicing....Pages 1845-1852
Magnetic Resonance Studies of Food Freezing....Pages 1869-1878
Nuclear Magnetic Resonance Studies on the Glass Transition and Crystallization in Low Moisture Sugars....Pages 1879-1888
Probing the Sensory Properties of Food Materials with Nuclear Magnetic Resonance Spectroscopy and Imaging....Pages 1889-1894
Single-Sided NMR in Foods....Pages 1895-1897
Applications of NMR in the Studies of Starch Systems....Pages 1899-1907
NMR Imaging of Bread and Biscuit....Pages 1795-1799
NMR Imaging of Dairy Products....Pages 1801-1806
NMR Imaging of Dough....Pages 1807-1812
MRI in Food Process Engineering....Pages 1813-1818
Rheo-NMR: Applications to Food....Pages 1819-1824
Temperature Measurements by Magnetic Resonance....Pages 1825-1830
High-Resolution Solid-State NMR as an Analytical Tool to Study Plant Seeds....Pages 1777-1781
High-Resolution Solid-State NMR Spectroscopy of Starch Polysaccharides....Pages 1783-1791