Models of Seizures and Epilepsy

Content: 
Front matter,Copyright,Contributors,Foreword,PrefaceEntitled to full textPart I: IntroductionChapter 1 - What Can We Model?, Pages 1-3, Asla Pitkänen, Aristea S. Galanopoulou, Solomon L. Moshé, Paul S. Buckmaster
Chapter 2 - Comparative Biology and Species Effects on Expression of Epilepsy, Pages 7-19, Paul S. Buckmaster
Chapter 3 - Strain Effects on Expression of Seizures and Epilepsy, Pages 21-38, Wolfgang Löscher, R.J. Ferland, T.N. Ferraro
Chapter 4 - Good Welfare Practice in Modeling Seizures and Epilepsy, Pages 39-46, John G.R. Jefferys
Chapter 5 - Ethics in the Use of Animal Models of Seizures and Epilepsy, Pages 47-68, Jerrold Tannenbaum
Chapter 6 - Regulatory Aspects for Drug Development, Pages 69-82, Lisa D. Coles, Henrik Klitgaard, Marie Kuker, James C. Cloyd
Chapter 7 - Use of Animal Models for Epilepsy Research and Therapy Development, Pages 83-94, Melissa Barker-Haliski, H. Steve White
Chapter 8 - Monitoring for Seizures in Rodents, Pages 97-109, Edward H. Bertram
Chapter 9 - Behavioral Characterization and Scoring of Seizures in Rodents, Pages 111-123, Jana Velíšková, Libor Velíšek
Chapter 10 - Seizure Mimics, Pages 125-137, Aristea S. Galanopoulou, Solomon L. Moshé
Chapter 11 - Characterization of Pathology, Pages 139-160, Eleonora Aronica, Angelika Mühlebner, Erwin A. van Vliet, Jan A. Gorter
Chapter 12 - Monitoring Cardiorespiratory and Other Physiological Parameters During Seizures in Small Animals, Pages 161-179, Mark Stewart, Jeffrey Goodman
Chapter 13 - Behavioral and Cognitive Testing Procedures in Animal Models of Epilepsy, Pages 181-196, Andrey M. Mazarati
Chapter 14 - In Vivo Imaging in Rodents, Pages 197-215, Olli Gröhn, Steven Deleye, Daniele Bertoglio, Stefanie Dedeurwaerdere
Chapter 15 - Hippocampal In Silico Models of Seizures and Epilepsy, Pages 219-232, Ivan Raikov, Ivan Soltesz
Chapter 16 - Neocortical/Thalamic In Silico Models of Seizures and Epilepsy, Pages 233-246, Fabrice Wendling, Fabrice Bartolomei, Julien Modolo
Chapter 17 - Genetic Epilepsy Modeling With Human Pluripotent Stem Cells, Pages 247-260, Louis T. Dang, Jack M. Parent
Chapter 18 - Hippocampus In Vitro, Pages 261-272, Anton I. Ivanov, Christophe Bernard
Chapter 19 - Thalamic Models of Seizures In Vitro, Pages 273-284, Frances S. Cho, Alexandra Clemente, Stephanie Holden, Jeanne T. Paz
Chapter 20 - Brain Slices From Human Resected Tissues, Pages 285-299, Uwe Heinemann, Siegrun Gabriel, Eskedar A. Angamo, Seda Salar, Thomas-Nicolas Lehmann, Nora Dengler
Chapter 21 - Organotypic Hippocampal Slice Cultures as a Model of Posttraumatic Epileptogenesis, Pages 301-311, Yevgeny Berdichevsky, Joseph Glykys, Volodya Dzhala, Kyle Lillis, Kevin J. Staley
Chapter 22 - The In Vitro Isolated Guinea Pig Brain in the Study of Ictogenesis, Pages 313-323, Marco de Curtis, Vadym Gnatkovsky, Laura Uva, Laura Librizzi
Chapter 23 - Nematode C. elegans: Genetic Dissection of Pathways Regulating Seizure and Epileptic-Like Behaviors, Pages 327-344, Seika Takayanagi-Kiya, Yishi Jin
Chapter 24 - Drosophila, Pages 345-358, Richard A. Baines, Carlo N.G. Giachello, Wei-Hsiang Lin
Chapter 25 - Xenopus laevis, Pages 359-367, Laura A. Jansen
Chapter 26 - Zebrafish Models of Epilepsy and Epileptic Seizures, Pages 369-384, Daniëlle Copmans, Aleksandra Siekierska, Peter A.M. de Witte
Chapter 27 - Naturally Occurring Epilepsy and Status Epilepticus in Dogs, Pages 387-398, Heidrun Potschka, Edward N. Patterson, Ilo E. Leppik
Chapter 28 - Naturally Occurring Temporal Lobe Epilepsy in Cats, Pages 399-411, Akos Pakozdy, Andrea Klang, Sibylle Kneissl, Peter Halasz
Chapter 29 - Naturally Occurring Epilepsy and Status Epilepticus in Sea Lions, Pages 413-425, Paul S. Buckmaster
Chapter 30 - Baboon Model of Genetic Generalized Epilepsy, Pages 427-440, Charles Á. Szabó, Felipe S. Salinas
Chapter 31 - Genetic Models of Reflex Epilepsy and SUDEP in Rats and Mice, Pages 441-453, Carl Faingold, Srinivasan Tupal, Prosper N’Gouemo
Chapter 32 - Genetic Models of Absence Epilepsy in Rats and Mice, Pages 455-471, Guillaume Jarre, Isabelle Guillemain, Colin Deransart, Antoine Depaulis
Chapter 33 - Electrical Stimulation Seizure Models, Pages 474-488, Erwin A. van Vliet, Jan A. Gorter
Chapter 34 - Systemic Chemoconvulsants Producing Acute Seizures in Adult Rodents, Pages 491-512, Jana Velíšková, Michael P. Shakarjian, Libor Velíšek
Chapter 35 - Focally Applied Chemoconvulsants, Pages 513-527, David C. Henshall
Chapter 36 - Models of Chemically-Induced Acute Seizures and Epilepsy: Toxic Compounds and Drugs of Addiction, Pages 529-551, Frederic Dorandeu, Guilhem Calas, Gregory Dal Bo, Raafat Fares
Chapter 37 - Pharmacologically Induced Animal Models of Absence Seizures, Pages 553-567, George K. Kostopoulos
Chapter 38 - Models of Seizures and Status Epilepticus Early in Life, Pages 569-586, Stéphane Auvin, Astrid Nehlig
Chapter 39 - Tetanus Toxin, Pages 589-598, Matthew C. Walker, John G.R. Jefferys, Robert C. Wykes
Chapter 40 - Post-Status Epilepticus Models: Systemic Kainic Acid, Pages 599-610, F. Edward Dudek, Kevin J. Staley
Chapter 41 - Poststatus Epilepticus Models: Focal Kainic Acid, Pages 611-624, David C. Henshall
Chapter 42 - The Pilocarpine Model of Acquired Epilepsy, Pages 625-636, Mary E. Kelly, Douglas A. Coulter
Chapter 43 - Post-Status Epilepticus Models: Electrical Stimulation, Pages 637-650, Jan A. Gorter, Erwin A. van Vliet
Chapter 44 - Poststatus Epilepticus Models: Hyperthermia, Pages 651-660, Nathalie T. Sanon, Tarek Shaker, Lionel Carmant
Chapter 45 - Epilepsy After Traumatic Brain Injury, Pages 661-681, Asla Pitkänen, Jenni Kyyriäinen, Pedro Andrade, Lotta Pasanen, Xavier Ekolle Ndode-Ekane
Chapter 46 - Postinfectious Epilepsy, Pages 683-696, Dipan C. Patel, Karen S. Wilcox
Chapter 47 - Modeling Hypoxia-Induced Seizures and Hypoxic Encephalopathy in Developing Brain, Pages 697-711, Hongyu Sun, Frances E. Jensen
Chapter 48 - Perinatal Hypoxic-Ischemic Encephalopathy: A Model of Stroke-Induced Pediatric Epilepsy, Pages 713-725, Jeffrey Bastar, Jay G. Spampanato, Shilpa D. Kadam, Andrew Zayachkivsky, Jeffrey Ekstrand, Kevin J. Staley, F. Edward Dudek
Chapter 49 - Poststroke Epilepsy, Pages 727-741, Kevin M. Kelly
Chapter 50 - Animal Models of Drug-Refractory Epilepsy, Pages 743-760, Wolfgang Löscher
Chapter 51 - Spontaneous and Gene-Directed Epilepsy Mutations in the Mouse, Pages 763-776, Jeffrey L. Noebels
Chapter 52 - Dravet and GEFS+ Syndromes, Pages 777-795, Kay L. Richards, Steve Petrou
Chapter 53 - Tuberous Sclerosis and Other mTORopathies, Pages 797-810, Anna Jeong, Michael Wong
Chapter 54 - Kindling: A Model and Phenomenon of Epilepsy, Pages 813-825, Thomas P. Sutula, Robert J. Kotloski
Chapter 55 - Human Mutations Associated With Brain Malformations Resulting in Hyperexcitability in Rodents, Pages 827-844, Valerio Conti, Renzo Guerrini
Chapter 56 - Dysplasias: Cortical Freeze Lesion, Pages 845-859, Lauren A. Lau, Chris G. Dulla
Chapter 57 - Dysplasia: MAM, Model of Developmental Epilepsy, Pages 861-876, Giorgio Battaglia, Adele Finardi, Paola Nobili, Francesca Colciaghi
Chapter 58 - In Utero Irradiation as a Model of Cortical Dysplasia, Pages 877-885, Dean D. Lin, Steven N. Roper
Chapter 59 - Undercut Cortex, Pages 887-898, Xiaoming Jin, Xingjie Ping
Chapter 60 - Brain Tumor-Related Epilepsy, Pages 899-910, Rüdiger Köhling
Chapter 61 - Withdrawal Seizures, Pages 911-931, Jamila Newton, Prosper N’Gouemo
Chapter 62 - Perimenstrual Seizures and Neurosteroid Withdrawal, Pages 933-940, Doodipala S. Reddy
Chapter 63 - Metabolic Disturbances: Hypo- and Hyperglycemic Seizures In Vivo and In Vitroa, Pages 941-949, Peter L. Carlen, Liang Zhang
Chapter 64 - Blood–Brain Barrier Disruption, Pages 951-959, Dan Z. Milikovsky, Daniela Kaufer, Alon Friedman
Chapter 65 - Experimental Models of Inflammation in Epilepsy Research, Pages 961-974, Teresa Ravizza, Silvia Balosso, Nicola Marchi
Chapter 66 - Infantile Spasms, Pages 977-993, Aristea S. Galanopoulou, Solomon L. Moshé
Chapter 67 - Models of Epileptic Encephalopathies, Pages 995-1005, Paul R. Jarvis, Gregory L. Holmes
Chapter 68 - SUDEP Animal Models, Pages 1007-1018, Alica M. Goldman, Gordon Buchanan, Isamu Aiba, Jeffrey L. Noebels
Chapter 69 - Epilepsy in Models of Alzheimer’s Disease, Pages 1021-1030, Heikki Tanila, Asla Pitkänen
Chapter 70 - Animal Models of Acquired Epilepsy and Tauopathies, Pages 1031-1041, Ping Zheng, Sandy Shultz, Chris Hovens, Terence J. O’Brien
Chapter 71 - Epilepsy in Other Neurodegenerative Disorders: Huntington’s and Parkinson’s Diseases, Pages 1043-1058, Ana M. Estrada-Sánchez, Michael S. Levine, Carlos Cepeda
Chapter 72 - Autism and Fragile X Syndrome, Pages 1059-1078, Heather O’Leary, Tim Benke
Chapter 73 - Epilepsy in Models of Rett Syndrome, Pages 1079-1090, James H. Eubanks
Chapter 74 - Models of Depressiona, Pages 1091-1104, Andrey M. Mazarati
Chapter 75 - What Do Models Model? What Needs to Be Modeled?, Pages 1107-1119, Aristea S. Galanopoulou, Asla Pitkänen, Paul S. Buckmaster, Solomon L. Moshé
Index, Pages 1121-1151