MicroRNAs in malignant tumors of the skin: First steps of tiny players in the skin to a new world of genomic medicine

Front Matter....Pages I-XI
Introduction....Pages 1-13
Objectives of this work....Pages 15-15
Summary and discussion of this work....Pages 17-52
Closing remarks....Pages 53-54
Paper 1: Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer....Pages 55-66
Paper 2: Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1 and TARBP2 in epithelial skin cancer....Pages 67-79
Paper 3: Expression of microRNAs in basal cell carcinoma....Pages 81-100
Paper 4: Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma....Pages 101-126
Paper 5: The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi....Pages 127-151
Paper 6: Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi....Pages 153-162
Paper 7: Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi....Pages 163-209
Paper 8: MicroRNAs and the skin: tiny players in the body’s largest organ....Pages 211-231
Paper 9: microRNA in non-melanoma skin cancer....Pages 233-245