Metabolic Interconversion of Enzymes

Front Matter....Pages I-XI
Welcoming Remarks....Pages 1-1
Metabolic Interconversion of Enzymes: Introductory Remarks....Pages 3-9
Comparative and Evolutionary Aspects of the Control of Phosphorylase....Pages 11-28
Electron Microscopy of Muscle Phosphorylases b and a ....Pages 29-49
Discussion....Pages 50-54
Studies on Glycogen Phosphorylase in Solution and in the Crystalline State....Pages 55-71
Probing and Mapping the Pyridoxal 5′-Phosphate Site of Glycogen Phosphorylase....Pages 73-101
Association-dissociation Properties of NaBH 4 -reduced Phosphorylase b ....Pages 103-112
The Mechanism of Action of Cyclic AMP in the Activation of Phosphorylase Kinase....Pages 113-117
Discussion....Pages 118-119
Phosphorylase a as a Glucose Receptor....Pages 121-132
Properties of Purified Glycogen Synthetase b from Liver....Pages 133-145
Discussion....Pages 146-147
The Mechanism of Activation of the Lac Operon....Pages 149-156
Discussion....Pages 157-157
Regulatory Mechanism of Enzyme Catabolism....Pages 159-174
Discussion....Pages 175-177
Interconversion of Two Forms of Leucyl-tRNA Synthetase....Pages 179-191
Discussion....Pages 192-192
Diphtheria Toxin-catalyzed Adenosine Diphosphoribosylation of Aminoacyl Transferase II from Rat Liver....Pages 193-207
Discussion....Pages 208-211
Regulation of Transcription by T4 Phage Induced Chemical Alteration and Modification of Transcriptase (EC2.7.7.6)....Pages 213-227
Discussion....Pages 228-229
On the Mechanism of Action and Metabolic Control of the Multifunctional Enzyme Complex that Catalyzes Adenylylation and Deadenylylation of Escherichia coli Glutamine Synthetase....Pages 231-244
Inactivation of Glutamine Synthetase in Intact E. coli Cells....Pages 245-252
Studies on the Mechanism of the ATP: Glutamine Synthetase Adenylyltransferase Reaction....Pages 253-260
The Role of Enzyme Inactivation in the Regulation of Glutamine Synthesis in Yeast: in vivo Studies Using 15 NH 3 ....Pages 261-276
Discussion....Pages 277-279
Molecular Aspects of the Regulation of the Mammalian Pyruvate Dehydrogenase Complex....Pages 281-291
Regulation of the Mammalian Pyruvate Dehydrogenase Complex: Physiological Aspects and Characterization of PDH-Phosphatase from Pig Heart....Pages 293-309
Discussion....Pages 310-317
Enzyme-dependent Activation of Pyruvate Formate-lyase of Escherichia coli ....Pages 319-326
Discussion....Pages 327-329
Lactose Synthetase: Structure and Function....Pages 331-346
UDP-glucose: D-fructose-6-phosphate 2-glucosyltransferase: Metabolic Control of the Enzyme Activity....Pages 347-351
Discussion....Pages 352-355
Mechanism of Interaction between Arginase and Ornithine Transcarbamoyl Transferase of Saccharomyces cerevisiae ....Pages 357-369
Discussion....Pages 370-373
Enzymatic Modification of Basic Chromosomal Proteins in Developing Trout Testis....Pages 375-376
Discussion....Pages 377-380
Active Site-directed Side Chain Modification....Pages 381-389
Discussion....Pages 390-390
Metabolic Interconversions of Enzymes: Relation to the Hysteretic Response....Pages 391-400
Discussion....Pages 401-404
Why Are Enzymes Interconvertible?....Pages 405-415
General Discussion....Pages 416-438
Back Matter....Pages 439-450