Metabolic Effects of Gonadal Hormones and Contraceptive Steroids

Front Matter....Pages i-xxix
Front Matter....Pages 1-1
Sex Hormones, the Gastrointestinal Tract and the Liver : Introductory Comments....Pages 3-10
Effect of Ethynyl Estradiol on Hepatic Excretory Function of the Rat....Pages 11-18
The Effect of Natural and Synthetic Estrogens on the Excretion of BSP by the Liver....Pages 19-29
Some Effects of Contraceptive Steroids on Hepatic Function in Normal Women and in Patients with Acquired and Inheritable Defects in Hepatic Excretory Function....Pages 30-39
Cholestasis of Pregnancy and during Ethinyl Estradiol Administration in the Human and Rat....Pages 40-58
δ-Aminolevulinate Synthetase of the Chick Embryo Liver: The Effect of Natural and Synthetic Sex Steroids on its Activity....Pages 59-67
The Effects of Progesterone Administration on Hepatic Endoplasmic Reticulum: An Electron Microscopic and Biochemical Study....Pages 68-85
The Role of Sex Hormones in the Metabolism of Drugs and Other Foreign Compounds by Hepatic Microsomal Enzymes....Pages 86-94
Front Matter....Pages 95-95
Effects of Gonadal Hormones and Contraceptive Steroids on Glucose and Insulin Metabolism....Pages 97-125
The Effect of Ovarian Steroids on Glucose, Insulin, and Growth Hormone....Pages 126-143
Insulin Production in Overt (Maturity-Onset) Diabetes: Absence of Hyperinsulinemia Despite Hyperglycemia Induced by Contraceptive Steroids....Pages 144-156
Longitudinal Studies of the Effects of Oral Contraceptive Therapy on Plasma Glucose, Non-Esterified Fatty Acid, Insulin and Blood Pyruvate Levels During Oral and Intravenous Glucose Tolerance Tests....Pages 157-177
Studies of Venous Blood Pyruvate and Lactate Levels During Oral and Intravenous Glucose Tolerance Tests in Women Receiving Oral Contraceptives....Pages 178-192
Acquired Subclinical Diabetes Mellitus in Women Receiving Oral Contraceptive Agents....Pages 193-203
Front Matter....Pages 205-205
Oral Contraceptives, Lipoproteins, and Lipid Transport....Pages 207-218
Fasting Serum Triglyceride and Cholesterol Levels During Oral Contraceptive Therapy....Pages 219-231
Studies on the Mechanism of Hypertriglyceridemia Induced by Oral Contraceptives....Pages 232-241
Possible Relationship between Plasma Lipids and Hormonal Steroids....Pages 242-246
Gonadal Steroid Effects on Serum Lipids....Pages 247-264
Effect of an Oral Contraceptive Steroid Mixture on Some Aspects of Lipid Metabolism in the Rat....Pages 265-274
Front Matter....Pages 275-275
Effects of Gonadal and Contraceptive Hormones on Protein and Amino Acid Metabolism....Pages 277-318
Metabolic Inhibitors and the Anabolic Actions of Testosterone Propionate....Pages 319-327
Androgen Regulation of Mouse Kidney RNA....Pages 328-338
Progesterone: Mechanism of Action....Pages 339-351
The Effects of Gonadal Hormones and Contraceptive Steroids on Tryptophan Metabolism....Pages 352-366
Certain Metabolic Effects of Estrogens....Pages 367-378
Front Matter....Pages 379-379
Effects of Gonadal Hormones and Contraceptive Steroids on Respiration....Pages 381-393
Respiratory Effects of Gonadal Hormones....Pages 394-402
Front Matter....Pages 403-403
Oral Contraceptives and High Blood Pressure: Changes in Plasma Renin, Renin Substrate and Aldosterone Excretion....Pages 405-421
The Effects of Gonadal Hormones on Water and Electrolyte Metabolism in the Human....Pages 422-433
Effect of Gonadal Hormones on Adrenocortical Secretion and Its Significance....Pages 434-445
Effects of Gonadal Hormones on Plasma Renin Activity and Aldosterone Excretion Rate....Pages 446-463
Properties and Origin of Uterine Renin....Pages 464-470
Interrelationships of Oral Contraceptives and Hypertension....Pages 471-475
Clinical Course and Laboratory Data in Hypertension Associated with Oral Contraceptives....Pages 476-481
Front Matter....Pages 483-483
The Effect of Oral Contraceptives on Calcium Absorption....Pages 485-492
Estrogen Effects on the Skeleton....Pages 493-502
Effects of Estrogen on Calcium Metabolism in Man....Pages 503-517
Effect of Estrogens on the Structure of Bone....Pages 518-529
Effects of Estrogens and Progesterones on Collagen Metabolism....Pages 530-535
Front Matter....Pages 537-537
Thromboembolism and Contraceptive Medication: Incidence and Mechanism....Pages 539-562
Effects on the Vascular System and Blood: Epidemiological Studies....Pages 563-579
Oral Contraceptives and Excess Mortality From Venous and Pulmonary Thromboembolism in the United States....Pages 580-585
Hypercoagulability....Pages 586-596
Influence of Hormones on Tissue and Blood Fibrinolytic Activity....Pages 597-618
Effect of Contraceptive Hormone Preparations on Plasma Fibrinolytic Activity....Pages 619-634
The Role of Blood Platelets in Thrombosis in Relation to the Effects of Contraceptive Steroids on Platelet Function....Pages 635-646
Front Matter....Pages 647-647
The Role of Progestins and Progesterone in Brain Function and Behavior....Pages 649-667
The Physiologic Basis for the Temperature Raising Effect of Progesterone....Pages 668-675
Assessment of Psychological Concomitants of Oral Contraceptives....Pages 676-705
Behavioral Effects of Gonadal Hormones and Contraceptive Steroids in Primates....Pages 706-721
Role of the Central Nervous System in The Control of Reproductive Mechanisms By Gonadal Steroids....Pages 722-728
Back Matter....Pages 729-762