Membrane Biogenesis and Protein Targeting

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Page iii

Copyright page
Page iv

List of contributors
Pages v-x

Chapter 1 Where are we in the exploration of Escherichia coli translocation pathways? Original Research Article
Pages 3-7
Bill Wickner

Chapter 2 Components involved in bacterial protein translocation Original Research Article
Pages 9-20
Chris Harris, Phang C. Tai

Chapter 3 Molecular characterization of Sec proteins comprising the protein secretory machinery of Escherichia coli Original Research Article
Pages 21-32
Shoji Mizushima, Hajime Tokuda, Shin-Ichi Matsuyama

Chapter 4 Distinct steps in the insertion pathway of bacteriophage coat proteins Original Research Article
Pages 33-47
Andreas Kuhn, Dorothee Troschel

Chapter 5 Steps in the assembly of a cytoplasmic membrane protein: the MalF component of the maltose transport complex Original Research Article
Pages 49-61
Beth Traxler, Jon Beckwith

Chapter 6 Structural characteristics of presecretory proteins: their implication as to translocation competency Original Research Article
Pages 63-74
Shoji Mizushima, Katsuko Tani, Chinami Hikita, Masashi Kato

Chapter 7 Sequence determinants of membrane protein topology Original Research Article
Pages 75-84
Gunnar Von Heijne

Chapter 8 Lipid involvement in protein translocation Original Research Article
Pages 85-101
B. De Kruijff, E. Breukink, R.A. Demel, R. Van T Hof, H.H.J. De Jongh, W. Jordi, R.C.A. Keller, J.A. Killian, A.I.P.M. De Kroon, R. Kusters, M. Pilon

Chapter 9 Membrane protein insertion into the endoplasmic reticulum: signals, machinery and mechanisms Original Research Article
Pages 105-118
Stephen High, Bernhard Dobberstein

Chapter 10 Translocation of proteins through the endoplasmic reticulum membrane: investigation of their molecular environment by cross-linking Original Research Article
Pages 119-127
Enno Hartmann, Tom A. Rapoport

Chapter 11 The role of GTP in protein targeting to the endoplasmic reticulum Original Research Article
Pages 129-136
Stephen C. Ogg, Jodi M. Nunnari, Joshua D. Miller, Peter Walter

Chapter 12 Consecutive steps of nucleoside triphosphate hydrolysis are driving transport of precursor proteins into the endoplasmic reticulum Original Research Article
Pages 137-146
Peter Klappa, Günter Müller, Gabriel Schlenstedt, Hans Wiech, Richard Zimmermann

Chapter 13 Mechanism and regulation of import and degradation of cytosolic proteins in the lysosome/vacuole Original Research Article
Pages 149-164
Hui-Ling Chiang, Randy Schekman

Chapter 14 The sorting of soluble and integral membrane proteins to the yeast vacuole Original Research Article
Pages 165-182
Christopher K. Raymond, Carol A. Vater, Steven Nothwehr, Christopher J. Roberts, Tom H. Stevens

Chapter 15 Defining components required for peroxisome assembly in Saccharomyces cerevisiae Original Research Article
Pages 185-207
Jörg Höhfeld, Daphne Mertens, Franziska F. Wiebel, Wolf-H. Kunau

Chapter 16 Structure and assembly of peroxisomal membrane proteins Original Research Article
Pages 209-220
Joel M. Goodman, Lisa J. Garrard, Mark T. McCammon

Chapter 17 Mechanisms of transport of proteins into microbodies Original Research Article
Pages 221-229
Suresh Subramani

Chapter 18 Lessons for peroxisome biogenesis from fluorescence analyses of Zellweger syndrome fibroblasts Original Research Article
Pages 231-237
Paul B. Lazarow, Hugo W. Moser, Manuel J. Santos

Chapter 19 The mitochondrial protein import machinery of Saccharomyces cerevisiae Original Research Article
Pages 241-251
Victoria Hines

Chapter 20 Protein insertion into mitochondrial outer and inner membranes via the stop-transfer sorting pathway Original Research Article
Pages 253-264
Gordon C. Shore, Douglas G. Millar, Jian-Ming Li

Chapter 21 General and exceptional pathways of protein import into sub-mitochondrial compartments Original Research Article
Pages 265-276
Roland Lill, Christoph Hergersberg, Helmut Schneider, Thomas Söllner, Rosemary Stuart, Walter Neupert

Chapter 22 Targeting of proteins into and across the chloroplastic envelope Original Research Article
Pages 279-288
H.-M. Li, S.E. Perry, K. Keegstra

Chapter 23 Transport of proteins into the thylakoids of higher plant chloroplasts Original Research Article
Pages 289-297
Colin Robinson

Chapter 24 Comparison of two different protein trans-location mechanisms into chloroplasts Original Research Article
Pages 299-306
Jürgen Soll, Heike Alefsen, Birgit Böckler, Birgit Kerber, Michael Salomon, Karin Waegemann

Chapter 25 DnaJ homologs and protein transport Original Research Article
Pages 309-327
Takao Kurihara, Pamela A. Silver

Chapter 26 Chaperonin-mediated protein folding Original Research Article
Pages 329-337
Arthur L. Horwich, Shari Caplan, Joseph S. Wall, F.-Ulrich Hartl

Index
Pages 339-343