Mechanisms of Drug Resistance in Neoplastic Cells. Bristol–Myers Cancer Symposia, Volume 9

Content: 
BRISTOL-MYERS CANCER SYMPOSIA, Page ii
Front Matter, Page iii
Copyright, Page iv
Contributors, Pages xiii-xix
Editor's Foreword, Page xxi, Stephen K. Carter
Foreword, Pages xxiii-xxiv, Richard L. Gelb
Preface, Page xxv, Paul V. Woolley III, Kenneth D. Tew
1 - Colon Cancer as a Model for Resistance to Antineoplastic Drugs, Pages 3-12, PAUL V. WOOLLEY III, SHAILENDRA KUMAR, TERRENCE J. MONKS, JORGE E. ORTIZ
2 - Mathematical Modeling of Drug Resistance, Pages 13-28, J.H. GOLDIE, A.J. COLDMAN
3 - On the Mechanism of Induced Gene Amplification in Mammalian Cells, Pages 29-40, ROBERT T. SCHIMKE, STEVEN SHERWOOD, RANDAL JOHNSTON, ANNA HILL, GLEN RICE, CYNTHIA HOY, JOHN FEDER, PEGGY FARNHAM
4 - Cellular Concomitants of Multidrug Resistance, Pages 41-68, JUNE L. BIEDLER, MARIAN B. MEYERS, BARBARA A. SPENGLER
5 - Resistance to Alkylating Agents: Basic Studies and Therapeutic Implications, Pages 69-86, EMIL FREI III, BEVERLY A. TEICHER, CAROL A. CUCCHI, ANDRE ROSOWSKY, JENNIFER L. FLATOW, MICHAEL J. KELLEY, PAUL GENEREUX
6 - Phosphoprotein and Protein Kinase C Changes in Human Multidrug-Resistant Cancer Cells, Pages 87-96, ROBERT L. FINE, KENNETH H. COWAN, BRUCE A. CHABNER, JAMES CARMICHAEL
7 - Novel Drugs That Affect Glutathione Metabolism, Pages 99-126, ALTON MEISTER
8 - Regulation of Genes Encoding Drug-Metabolizing Enzymes in Normal and Preneoplastic Tissues, Pages 127-139, CECIL B. PICKETT, CLAUDIA A. TELAKOWSKI-HOPKINS, GLORIA J.-F. DING, VICTOR D.-H. DING
9 - Glutathione S-Transferases and Anticancer Drug Resistance, Pages 141-159, KENNETH D. TEW, MARGIE L. CLAPPER
10 - Cellular Resistance to Cyclophosphamide, Pages 161-171, MICHAEL COLVIN, JOHN HILTON
11 - Preclinical and Clinical Experiences with Drug Combinations Designed to Inhibit DNA Repair in Resistant Human Tumor Cells, Pages 173-182, LEONARD C. ERICKSON, KENNETH C. MICETICH, RICHARD I. FISHER
12 - Modification of the Cytotoxicity of DNA-Directed Chemotherapeutic Agents by Polyamine Depletion, Pages 183-194, LAURENCE J. MARTON
13 - Multidrug Resistance and P-Glycoprotein Expression, Pages 197-209, VICTOR LING, PETER F. JURANKA, JANE A. ENDICOTT, KATHRYN L. DEUCHARS, JAMES H. GERLACH
14 - Different Mechanisms of Multiple Drug Resistance in Two Human Leukemic Cell Lines, Pages 211-222, WILLIAM T. BECK, MARY K. DANKS, JOHN M. ZAMORA, MARGARET C. CIRTAIN, JACK C. YALOWICH
15 - Multidrug Resistance in the Mouse Macrophage-Like Cell Line J774.2, Pages 223-242, SUSAN BAND HORWITZ, STEPHANIE GOEI, LEE GREENBERGER, LEONARD LOTHSTEIN, WILFREDO MELLADO, SAMAR N. ROY, CHIA-PING H. YANG, RON ZEHEB
16 - Expression, Amplification, and Transfer of DNA Sequences Associated with Multidrug Resistance, Pages 243-257, MICHAEL M. GOTTESMAN, IRA PASTAN, SHIN-ICHI AKIYAMA, ANTONIO T. FOJO, DING-WU SHEN, KAZUMITSU UEDA, CAROL O. CARDARELLI, NANCY D. RICHERT, MARK C. WILLINGHAM, MARILYN M. CORNWELL, DOUGLAS P. CLARK, JANICE E. CHIN, CHANG-JIE CHEN, KYUNGHEE CHOI, RENA SOFFIR, IGOR B. RONINSON
17 - Cytogenetic and Molecular Biologic Alterations Associated with Anthracycline Resistance, Pages 259-276, JEFFREY M. TRENT, MARILYN L. SLOVAK, ANNA B. HILL, PAUL S. MELTZER, WILLIAM S. DALTON, WILLIAM T. BECK, SUSAN P.C. COLES
18 - Roles of DNA Topoisomerases in Drug Cytotoxicity and Drug Resistance, Pages 277-286, ANNETTE L. BODLEY, LEROY F. LIU
Manipulation of Cellular Thiols to Influence Drug Resistance, Pages 289-306, ROBERT F. OZOLS, THOMAS C. HAMILTON, HIDETAKA MASUDA, ROBERT C. YOUNG
20 - Drug Resistance as a Focus for New Drug Design, Pages 307-328, K.R. HARRAP, M. JONES, P.M. GODDARD, R.M. ORR, Z.H. SIDDIK
21 - Manipulation of Drug Accumulation: Mechanisms to Overcome Resistance, Pages 329-345, HAïM TAPIERO, DOMINIQUE BOULE, NICOLE ITTAH-CORCOS, ALAIN FOURCADE, THEODORE J. LAMPIDIS
22 - Manipulation of Antineoplastic Drug Sensitivity and Resistance by DNA Transfection, Pages 347-370, JOHN S. LAZO, SUSAN L. KELLEY, JOHN E. MIGNANO
23 - Potential Use of Monoclonal Antibody–Drug Conjugates to Prevent Drug Resistance, Pages 371-383, CARL-WILHELM VOGEL, REINHARD BREDEHORST, MOUNANANDHAM PANNEERSELVAM, CAROLE J. SPANGLER
Index, Pages 385-390