Mechanisms in B-Cell Neoplasia: Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD,USA,March 24–26,1986

Front Matter....Pages I-XII
c- Myc -Induced Lymphomagenesis in Transgenic Mice and the Role of the Pvt -1 Locus in Lymphoid Neoplasia....Pages 1-8
Lymphohematopoietic and Other Malignant Neoplasms Occurring Spontaneously in Transgenic Mice Carrying and Expressing MTV/myc Fusion Genes....Pages 9-16
Tumors of Newborn NFS/N Mice Infected with Murine Retroviruses Containing Avian v- Myc ....Pages 17-22
Induction of Clonal Monocyte/Macrophage Tumors in vivo by a Mouse c- myc Retrovirus: Evidence for Secondary Transforming Events....Pages 23-32
Induction of Hematopoietic Tumors Using a Viral Construct Containing c- myc cDNA from Normal Mouse Spleen....Pages 33-39
Rapid Induction of Plasmacytomas in Mice by Pristane and a Murine Recombinant Retrovirus Containing an Avian v- myc and a Defective raf Oncogene....Pages 40-43
Transformation and Insertional Mutagenesis In Vitro of Primary Hematopoietic Stem Cell Cultures....Pages 44-54
Mammalian Cell Transformation by a Recombinant Murine Retrovirus Containing the Avian Erythroblastosis Virus erb B Gene....Pages 55-61
Determinants of Abelson Murine Leukemia Virus Pathogenesis....Pages 62-74
An In Vitro Model for Tumor Progression in Murine Lymphoid Cells....Pages 75-80
Structural Modification of c- abl in Lymphoma and Leukemia....Pages 81-89
Transposable Elements and Cancer....Pages 90-97
Alpha-type B Cell Growth Factor and Complement Component C3: Their Possible Structural Relationship....Pages 98-104
A Growth-Factor Dependent B-Cell Hybridoma....Pages 105-113
A Growth Factor Required by Plasmacytoma Cells In Vitro ....Pages 114-120
Genes Affecting the Production or Action of B Cell-Active Lymphokines....Pages 121-126
Lymphokine Regulation of Murine IgE Production....Pages 127-132
Interleukin-4 (B Cell Growth Factor-II/Eosinophil Differentiation Factor) is a Mitogen and Differentiation Factor for Preactivated Murine B Lymphocytes....Pages 133-141
Role of the LFA-1 Molecule in B Cell Differentiation....Pages 142-145
Studies on Transferrin Receptor Expression in Mouse Plasmacytoma Cells....Pages 146-147
Studies on Transferrin Receptor Expression in Mouse Plasmacytoma Cells....Pages 148-152
Structure and Expression of c- myb Protooncogene mRNA in Murine B-Cells....Pages 153-158
Genomic Activity and Translocation in Lymphocytes....Pages 159-161
Possible Role of Immunoglobulin Recombination Sequences in the Genesis of Variant t(2;8) Translocations of Burkitt Lymphoma....Pages 162-168
C-Myc Activation in Spontaneous Rat Immunocytomas Containing a 6;7 Chromosomal Translocation....Pages 169-174
The Molecular Genetics of Human T Cell Leukemias and Lymphomas....Pages 175-182
Molecular Genetics of Human B-cell Neoplasia....Pages 183-192
c- myc and Functionally Related Oncogenes Induce Both High Rates of Sister Chromatid Exchange and Abnormal Karyotypes in Rat Fibroblasts....Pages 193-201
Chromosomal Radiosensitivity During G 2 Phase and Susceptibility to Plasmacytoma Induction in Mice....Pages 202-208
Normal and Neoplastic B Cell Development in the Bursa of Fabricius....Pages 209-214
Restrictions That Influence Avian Leukosis Virus-Induced Lymphoid Leukosis....Pages 215-220
Benign Monoclonal Gammapathy (BMG)....Pages 221-224
DNA Rearrangement and Expression of the c-myc Gene in a Human Myeloma....Pages 225-226
Inbred Strain Differences Influence the Focal Proliferation of Plasma Cells in Pristane Induced Oil Granuloma....Pages 227-230
Molecular Analysis of myc Gene Mutants....Pages 231-236
Induction of fgr Proto-oncogene mRNA in B Lymphocytes as a Consequence of Epstein-Barr Virus Infection....Pages 237-245
Epstein-Barr Virus Induced Differentiation of Early B-Lineage Cells....Pages 246-250
Epstein-Barr Virus Gene Expression During Primary B-Lymphocyte Infection, in Transformed and Burkitt Lymphoma-Derived Cell Lines....Pages 251-256
Structure and Expression of Translocated c-myc Oncogenes: Specific Differences in Endemic, Sporadic and AIDS-Associated Forms of Burkitt Lymphomas....Pages 257-265
EBV-Activation of Human B-Lymphocytes....Pages 266-271
 Myc Expression in vivo During Human Embryogenesis....Pages 272-279
Expression of c- myc and c- fos During Phorbol Ester Induced Differentiation of B-type Chronic Lymphocytic Leukemia Cells....Pages 280-289
Regulation of c- myc mRNA and Protein Levels During Activation of Normal Human B Cells....Pages 290-296
Differential Expression of N-myc, c-myc and c-src Proto-oncogenes During the Course of Induced Differentiation of Murine Embryonal Carcinoma Cells....Pages 297-304
Complex Regulation of c-myc Gene Expression in a Murine B Cell Lymphoma....Pages 305-312
Activation of Proto-oncogene Expression by Growth Regulatory Signals....Pages 313-319
Biological Effects of High Level c-myc Expression in FR3T3 Fibroblasts....Pages 320-326
A Transfected c- myc Oncogene Inhibits Mouse Erythroleukemic Differentiation....Pages 327-330
Altered c-myc RNA Metabolism in Burkitt’s Lymphomas and Mouse Plasmacytomas....Pages 331-338
Mutations which Stabilize myc Transcripts and Enhance myc Transcription in Two Mouse Plasmacytomas....Pages 339-344
Studies on c- myc Regulation in Normal and Transformed Cells....Pages 345-354
Characterization and Nuclear Localization of the v- and c- myc Proteins....Pages 355-361
Characterisation of Human myc Proteins....Pages 362-374