Measurement of Risks

Front Matter....Pages i-x
Front Matter....Pages 1-1
The Risks of Measuring Risk....Pages 3-8
Front Matter....Pages 9-12
The Proper Interpretation of Significance Tests in Risk Assessment....Pages 13-28
Remarks on Sequential Designs in Risk Assessment....Pages 29-47
Epidemiologic Studies of Toxic Response — Significance Requirements....Pages 49-69
Biological Models in Epidemiology: Radiation Carcinogenesis....Pages 71-105
Front Matter....Pages 107-110
Dose-Response Relationships for Adult and Prenatal Exposures to Methylmercury....Pages 111-130
Risk Factors for Deficits in Early Cognitive Development....Pages 131-142
Utilization of Critical Periods During Development to Study the Effects of Low Levels of Environmental Agents....Pages 143-162
Epidemiologic Studies of Enviromental Exposures in Human Reproduction....Pages 163-188
Front Matter....Pages 189-191
Health Risks of Lead as Judged from Autopsy Material....Pages 193-210
Use of Tests of Pulmonary Function to Measure Effects of Air Pollutants....Pages 211-230
Experimental Evaluation of Air Pollutants in Humans as a Basis for Estimating Risk....Pages 231-251
Problems and Possibilities of Determining the Carcinogenic Potency of Inhalable Fibrous Dusts and Polycyclic Aromatic Hydrocarbons....Pages 253-279
Front Matter....Pages 281-283
Some Probabilistic Aspects of Safety Assessment....Pages 285-294
What is the Total Risk of Energy Systems?....Pages 295-319
Have the Nuclear Power Risk Assessors Failed?....Pages 321-341
Front Matter....Pages 343-345
Cytogenetic Bases for Risk Inference....Pages 347-360
Problems and Solutions in the Estimation of Genetic Risks from Radiation and Chemicals....Pages 361-384
Evaluation of Genetic Risks....Pages 385-407
Front Matter....Pages 409-413
Extrapolation from Long Term Low Dose Animal Studies — I. Review....Pages 415-441
Front Matter....Pages 409-413
Extrapolation from Long Term Low Dose Animal Studies — II. The ED 01 Study....Pages 443-475
The Shapes of the Radiation Dose-Mutation Response Curves in Drosophila: Mechanisms and Implications....Pages 477-496
The Cancer Risk from Low Level Radiation....Pages 497-519
A Simple Threshold Model for the Classical Bioassay Problem....Pages 521-533
A Biological Basis for the Linear Non-Threshold Dose-Response Relationship for Low-Level Carcinogen Exposure....Pages 535-544
Back Matter....Pages 545-550