Maturation Phenomenon in Cerebral Ischemia V: Fifth International Workshop April 28–May 1, 2002 Banff, Alberta, Canada

Front Matter....Pages I-XX
Front Matter....Pages 1-1
Modulation of Neuronal Death by the Transcription Factor E2F1 in Experimental Stroke....Pages 3-12
Brain Genomic Responses to Ischemic Stroke, Hemorrhage, Seizures, Hypoglycemia and Hypoxia....Pages 13-36
Temporal Profile of Gene Induction After Venous Ischemia and Effects of Spreading Depression....Pages 37-41
The Role of Protein Phosphatases Type 2 C in Neuronal Apoptosis....Pages 43-51
Mitochondrial Cytochrome C- and Smac-Dependent Apoptosis in Cerebral Ischemia: Role of Oxidative Signaling....Pages 53-61
Erythropoietin: A Beneficial Approach to Neuroprotection in Stroke....Pages 63-64
Transgenic Mutants for the Investigation of Molecular Stroke Mechanisms....Pages 65-77
Front Matter....Pages 79-79
Compartmentalization in Focal Cerebral Ischemia....Pages 81-93
Modulation of the Post-Ischemic Immune Response Improves Outcome in Focal Cerebral Ischemia: A Role for Lymphocytes in Stroke?....Pages 95-104
Tumor Necrosis Factor-Alpha (TNF-a) and Ceramide Induce Tolerance to Ischemic and Hypoxic Insults to Brain and Brain Cells Associated with Changes in NF к B Function....Pages 105-111
Microglial Proliferation and Cell Cycle Protein Upregulation in the Rat Hippocampus Following Forebrain Ischemia....Pages 113-119
A Role for Cerebrovascular Endothelium in Ischemia and Reperfusion....Pages 121-132
Neural Stem Cells: Developmental Lessons May Yield Therapeutic Insights....Pages 133-133
Front Matter....Pages 135-135
Experimental Neuroprotection: Translation to Human Stroke Trials....Pages 137-156
Front Matter....Pages 157-157
Acid-Sensitive Ion Channels in Brain: New Modulation of Ischemic Injury....Pages 159-165
In-Vitro Elucidation of Mechanisms Underlying Cell Swelling and Death of Nerve and Glial Cells....Pages 167-175
Endogenous Protection Against Hypoxia/ Ischemia in the Brain via Erythropoietin....Pages 177-187
Ultrastructural Temporal Profile of the Dying Neuron and Surrounding Astrocytes in the Ischemic Penumbra: Apoptosis or Necrosis?....Pages 189-196
The Maturation Phenomenon as an Expression of C.&O. Vogt’s Theory of Pathoclisis....Pages 197-203
Protection by Apomorphine of Dopaminergic Neurons Following Acute Inhibition of Oxidative Metabolism in Rodents....Pages 205-213
Front Matter....Pages 215-215
Marrow Stromal Cells as Restorative Treatment of Neural Injury....Pages 217-223
Protein Aggregation, Unfolded Protein Response and Delayed Neuronal Death after Brain Ischemia....Pages 225-237
Slow Progression of Neurologic Impairment after Mild Ischemic Insult in Rodents: Relationship to Metabolic and Histologic Changes....Pages 239-244
Comparison of Light Transparency Changes in the Cerebral Cortex during Focal Ischemia and Death....Pages 245-250
Sphingolipids Metabolism Following Cerebral Ischemia....Pages 251-263
Preconditioning of Gerbil Brain Reduces Hippocampal Depolarization Time Following Transient Forebrain Ischemia: Relationship to Hippocampal CA1 Neuron Injury....Pages 265-273
The Expression of MMPs in CNS Injury has Beneficial Roles....Pages 275-275
Front Matter....Pages 277-277
Postischemic Hypothermia Fails to Improve Outcome after a Striatal Hemorrhage in Rats....Pages 279-284
Activation of NG2-Positive Oligodendrocyte Progenitor Cells after Focal Ischemia in Rat Brain....Pages 285-296
Postischemic Housing in an Enriched Environment Influences Hippocampal Progenitor Cell Differentiation after Focal Cortical Ischemia....Pages 297-308
Front Matter....Pages 309-309
Estrogen Protects Against Global Ischemia-Induced Neuronal Death and Prevents Activation of Apoptotic Signaling Cascades in the Hippocampal CA1....Pages 311-311
Ischemic Preconditioning Prevents Global Ischemia-Induced Downregulation of the AMPA Receptor GluR2 Subunit in the Hippocampal CA1 but does not Block Caspase-3 Activation nor Protect against GluR2 Antisense Knockdown....Pages 313-313
Acute Recovery and Delayed Changes in Tissue Following Transient Cerebral Hypoxia-Ischemia:Impedance,Electron Microscopy and MR Imaging Studies in Rats....Pages 315-316
A Selective Thrombin Inhibitor Prevents Thrombin-Induced Neuronal Cell Death and Mild Hypothermia Enhances its Neuroprotective Effects Following Transient Focal lschemia in Rats....Pages 317-318
Zinc Dynamics in the Cerebral Cortex of Adult Mice Following Photothrombotic Stroke....Pages 319-320
Persistent Neuroprotection Against Focal Cerebral Ischemia Induced By Cortical Spreading Depression In Mice....Pages 321-322
Anatomical, Morphological and Behavioral Assessments of Four Different Models of Stroke....Pages 323-324
Effects of Endurance Exercise on Recovery Following Focal Ischemic Infarct....Pages 325-325
Leukocyte Rolling and Adhesion in Pial Microvessels Following Cerebral Ischemia in the Mouse: Effects of Hypothermia....Pages 327-329
Early Hypoxic-Ischemic Changes in Blood Flow, T1 Relaxation Time, Apparent Diffusion Coefficient and Water Content in Neonatal Rat Brain....Pages 331-332
Front Matter....Pages 309-309
Increased Expression of nNos Following Cortical Spreading Depression in Rat Brain....Pages 333-334
Regional Differences on Free Fatty Acid Accumulations between Upper and Lower Frontal Cortex in Rat Focal Ischemia....Pages 335-336
Cerebral Ischemia and the Rat Motor Cortex: Time Course of Dysfunction and the Effects of Differential Rehabilitation Paradigms on Functional Recovery....Pages 337-338
Rehabilitation-Induced Cortical Dysfunction Following Focal Ischemic Infarct....Pages 339-339
Behavioral Improvement by Activation of Endogenous Progenitors in the Rat Transient Forebrain Ischemia Model....Pages 341-342
Front Matter....Pages 343-343
5 th International Workshop Maturation Phenomenon in Cerebral Ischemia Round Table Discussion....Pages 345-359
Back Matter....Pages 361-362