Marine medicinal foods: implications and applications, animals and microbes

Series Page......Page 1
Copyright......Page 2
Contributors
......Page 3
Preface......Page 8
Medicinal Foods from Marine Animals: Current Status and Prospects......Page 10
Introduction......Page 11
Fish......Page 12
Crustaceans......Page 15
Other Marine Animals of Medicinal Value......Page 16
References......Page 17
Nutraceutical Functionalities of Polysaccharides from Marine Invertebrates......Page 19
Introduction......Page 20
Sea cucumbers......Page 22
Ascidians......Page 26
Sea urchins......Page 29
Nudibranchs......Page 30
References......Page 33
Marine By-product Phospholipids as Booster of Medicinal Compounds......Page 39
Marine Phospholipid must be More Effective than Fish Oil TG on Health Benefits......Page 40
Boosting Effect on Cancer Cell Differentiation......Page 43
Boosting Effect on Cancer Suppression......Page 46
Boosting Effect on Antiobesity Compounds......Page 49
References......Page 53
Characterization of Bioactive Peptides Obtained from Marine Invertebrates......Page 55
Introduction......Page 56
Preparation of Bioactive Peptides from Invertebrates......Page 57
The mechanism of hypertensive......Page 58
Shellfish......Page 60
Crustaceans......Page 62
Other invertebrates......Page 65
Pathogenic mechanism of AD: Amyloid cascade hypothesis......Page 66
Marine zooplankton......Page 68
Shellfish......Page 69
Marine zooplankton......Page 70
Other invertebrates......Page 72
Antimicrobial Activity......Page 73
Conclusion......Page 75
References......Page 76
Bioactive Marine Peptides: Nutraceutical Value and Novel Approaches......Page 81
Introduction......Page 82
Effect of The Structural Properties of Peptides on Bioactivity......Page 83
Bioactive Peptides Derived from Marine Fish......Page 87
Bioactive Peptides Derived from Lobster, Shrimp, and Crabs......Page 91
Bioactive Peptides Derived from Mollusks and Oysters......Page 92
Fermented Marine Peptides and Novel Approaches......Page 95
Concluding Remarks......Page 104
References......Page 107
Chitosan and Fish Collagen as Biomaterials for Regenerative Medicine......Page 114
General Properties of Scaffold for Regenerative Medicine......Page 115
Molecular weight and degree of deacetylation......Page 116
Compression test......Page 118
Degeneration temperature......Page 119
Cross-linking for stability......Page 120
Collagen......Page 121
Chitosan......Page 122
References......Page 123
Chitosan as Potential Marine Nutraceutical......Page 128
Introduction......Page 129
Chitosan from other sources......Page 130
Antioxidant activity......Page 132
Hypocholesterolemic effects......Page 133
Antimicrobial activity......Page 135
Anti-inflammatory activity......Page 136
Other biological properties......Page 138
References......Page 139
Bioactive Compounds from Marine Sponges and Their Symbiotic Microbes: A Potential Source of Nutraceuticals......Page 143
Introduction......Page 144
Marine Sponges and Their Symbiotic Microbes......Page 146
Anti-inflammatory compounds......Page 147
Hypocholesterolemic compounds......Page 150
Natural pigments......Page 152
Sustainable Production of Sponge Metabolite......Page 153
References......Page 154
Medicinal Benefits of Marine Invertebrates: Sources for Discovering Natural Drug Candidates......Page 158
Introduction......Page 159
Phylum Porifera......Page 161
Phylum Cnidaria......Page 162
Phylum Bryozoa......Page 163
Phylum Molluska......Page 164
Phylum Arthropoda......Page 167
Limitations of Marine Invertebrates as Source for Health Foods and Drug Candidates......Page 168
References......Page 169
Sea-Originated Cytotoxic Substances......Page 175
Halichondrins, Antitumor Compounds from Halichondria Okadai......Page 176
Cytotoxic Compounds Related to the Coral Community......Page 179
Cytotoxic Compounds from Cyanobacteria......Page 184
References......Page 186
Secondary Metabolites with New Medicinal Functions from Marine Organisms......Page 189
Halichlorine, A Bioactive Marine Natural Compound Isolated from A Marine Sponge H. Okadai Kadota......Page 190
Halichlorine inhibits LPS-induced NF-kappab activation in endothelial cells......Page 191
Halichlorine inhibits L-type Ca2+ channels in vascular smooth muscle cells......Page 193
References......Page 195
Structure-Function Relationship of Anticoagulant and Antithrombotic Well-Defined Sulfated Polysaccharides from Marine Invertebrates......Page 198
Introduction to Marine Sulfated Polysaccharides: A High Tendency for Regular Chemical Structures in Invertebrates.........Page 199
The Interaction of MSPs with Coagulation co-factors: Prevention of Blood Coagulation......Page 203
An example of influence by sugar type......Page 204
An example of preferential conformation binding......Page 207
An example of influence by sulfation pattern......Page 208
Remark Conclusions......Page 209
References......Page 210
Health Benefits of n-3 Polyunsaturated Fatty Acids: Eicosapentaenoic Acid and Docosahexaenoic Acid......Page 213
Sources and Intakes of Eicosapentaenoic Acid and Docosahexaenoic Acid......Page 214
Health Benefits of n-3 PUFAs......Page 215
n-3 PUFAs and cardiovascular diseases......Page 216
Anti-inflammatory Effects of EPA and DHA......Page 217
n-3 PUFAs and Metabolic Disorders......Page 218
Health Concerns......Page 220
References......Page 221
Biological Importance and Applications of Squalene and Squalane......Page 225
Background......Page 226
Biological Roles of Squalene and Squalane......Page 227
Antioxidant......Page 228
Anticancer......Page 229
Skin care......Page 230
Drug delivery agent......Page 231
Detoxifier......Page 232
Conclusion......Page 233
References......Page 234
Development of Bioactive Peptides from Fish Proteins and Their Health Promoting Ability......Page 236
Introduction......Page 237
Structure-activity Relationship of Fish Peptides......Page 238
Peptides from fish skin collagen and gelatin......Page 239
Production of Peptides from Various Fish Body Parts......Page 240
Antioxidant activity......Page 241
Antimicrobial activity......Page 242
Anticancer effect......Page 244
Future Trends of Peptides from Fish Proteins......Page 245
References......Page 246
Marine Fish-Derived Bioactive Peptides as Potential Antihypertensive Agents......Page 250
Introduction......Page 251
Antihypertensive Activity of Bioactive Peptides Derived from Marine Fishes......Page 252
Acknowledgment......Page 258
References......Page 259