Managing hazardous reactions and compounds in process chemistry

Content: 1. Managing Hazards for Scale Up of Chemical Manufacturing Processes 
 2. Safety by Design, The Bedrock for Managing Process Hazards 
 3. Strategies for Safely Handling Industrial Azide Reactions: The Three 
 Traps 
 4. Chemical Reaction Safety in the Research Laboratory ? Where It All 
 Begins 
 5. Systems and Protocols for Evaluating Hazardous Reaction Issues During 
 Early Stage Chemistry 
 6. Process Safety in the Large-Scale Manufacture of an Adamantane 
 ?-Ketoacid Precursor of Saxagliptin 
 7. Thermal Risk Assessment: A Powerful Tool for Route Selection for 
 Scale-Up Applied to Diels-Alder Reactions 
 8. Rapid Scale Up Using Hazardous Reagents: The Challenge of Risk 
 Mitigation 
 9. Development of a Multi-Kilogram Procedure To Prepare, Use, and Quench 
 Ethyl Diazoacetate 
 10. Synthesis and Processing of Energetic Materials - Considerations for Safe 
 Scale-up of Potentially Hazardous Reactions 
 11. Addressing Process Safety Hazards: Replacement of para-Methoxybenzyl 
 Chloride Leads to a Safer and Shorter Route 
 12. Managing Hazardous Reactions and Compounds in Process Chemistry 
 13. A New Paradigm in Oxidative Cleavage Reaction: The Use of Continuous 
 Reactors To Enable Safe Scale Up of Ozonolysis 
 14. Development of Flow Processes for the Syntheses of N-Aryl Pyrazoles and 
 Diethyl Cyclopropane-cis-1,2-dicarboxylate 
 15. Technology for Continuous Production of Fine Chemicals 
 16. Continuous Flow Chemistry of Metal Mediated Carboxylation and 
 ?-Arylation Reactions