Lung and Heart-Lung Transplantation

Front Cover......Page 1
Introduction......Page 14
Preface......Page 16
Contributors......Page 22
Contents......Page 30
1.  Historical Overview of Lung and Heart–Lung Transplantation......Page 44
2.  Basic Immunological Concepts in Lung Transplantation: The Role of Regulatory T Cells and Dendritic Cells......Page 64
3.  Allogeneic Recognition and Immune Tolerance in Lung Transplantation......Page 90
4.  Lung Transplantation for Chronic Obstructive Pulmonary Disease......Page 104
5.  Lung Transplant in Cystic Fibrosis......Page 164
6.  Pulmonary Arterial Hypertension and Lung Transplantation......Page 190
7.  Lung Transplantation for Interstitial Lung Disorders......Page 208
8.  Pulmonary Langerhans Cell Histiocytosis and Lymphangioleiomyomatosis......Page 248
9.  Pediatric Lung Transplantation......Page 276
10.  Living Lobar Lung Transplantation......Page 298
11.  Heart–Lung Transplantation: Is It a Viable Option in the 21st Century?......Page 312
12.  Lung Allocation in the United States......Page 328
13.  Organ Allocation and Donor Availability—The European Experience......Page 344
14.  Allocation of Donor Organs for Lung Transplantation: The Australian Experience......Page 350
15.  Lung Preservation Techniques......Page 368
16.  Operative Techniques Utilized in Lung Transplantation and Strategies to Increase the Donor Pool......Page 392
17.  Immunosuppressive Drugs: Cyclosporine, Tacrolimus, Sirolimus, Azathioprine,Mycophenolate Mofetil, and Corticosteroids......Page 406
18.  Lympholytic Agents (Polyclonal Antilymphocyte Antibodies, Anti-CD3 Monoclonal Antibodies, Anti-CD25 Monoclonal Antibodies)......Page 444
19.  Novel and Future Approaches to Immunosuppression......Page 464
20.  Primary Graft Dysfunction Following Lung Transplantation: Pathogenesis and Impact on Early and Late Outcomes......Page 480
21.  Airway Complications in Lung Transplantation......Page 508
22.  Viral Infections Complicating Lung and Solid Organ Transplantation......Page 528
23.  Coccidioidomycosis After Solid Organ Transplantation......Page 570
24.  Histoplasmosis and Blastomycosis After Solid Organ Transplantation......Page 592
25.  Invasive Fungal Infections Complicating Lung and Solid Organ Transplantation: Aspergillosis, Cryptococcosis, and Molds......Page 600
26.  Bacterial Infections and Pneumocystis Infections......Page 630
27.  Legionella in Solid Organ Transplantation......Page 650
28.  Mycobacterial Infections Complicating Organ Transplantation......Page 666
29.  Acute Allograft Rejection......Page 704
30.  Pathology of the Lung Transplant......Page 726
31.  Obliterative Bronchiolitis......Page 766
32.  The Role for Alloimmune and Nonalloimmune Injury and Cytokine Responses in the Pathogenesis of Bronchiolitis Obliterans Syndrome......Page 796
33.  Pulmonary Physiology Posttransplant......Page 832
34.  Imaging of the Posttransplant Lung......Page 866
35.  Cardiac, Lipid, and Atherosclerotic Complications Among Lung and Heart–Lung Recipients......Page 924
36.  Metabolic Bone Disease in Lung Transplant Recipients......Page 938
37.  Lymphoproliferative Disorders Complicating Solid Organ Transplantation......Page 944
Index......Page 978