Living Related Transplantation

Contents......Page 6
Contributors......Page 10
Foreword......Page 14
Introduction......Page 18
Safety......Page 19
Donor’s feelings about donation......Page 23
Recipient’s feelings about donation......Page 24
Donor approach, consent and evaluation......Page 25
Donor/transplant team’s autonomy......Page 28
Live unrelated donation......Page 30
Donation by strangers......Page 31
Commercialization of organ donation......Page 32
Donor rewards......Page 37
Surrogate consent......Page 38
Paired-exchange programmes......Page 40
Minor donors......Page 41
Conclusion......Page 44
References......Page 45
Introduction......Page 56
Donor evaluation......Page 57
Medical evaluation......Page 58
Surgical evaluation......Page 59
Assessment of renal function......Page 61
Donor age......Page 62
Obesity......Page 63
Open donor nephrectomy......Page 64
Mini-open donor nephrectomy (MODN)......Page 65
Hand-assisted laparoscopic donor nephrectomy......Page 67
Pure laparoscopic donor nephrectomy......Page 68
Donor risks......Page 69
Donor outcome......Page 71
Ways of expanding the living-donor pool......Page 73
Conclusions......Page 74
References......Page 75
History......Page 82
Donor Evaluation......Page 84
Donor Left Hepatectomy......Page 89
Recipient Hepatectomy and Left-Liver Graft Implantation......Page 93
Donor Right Hepatectomy......Page 95
Recipient Hepatectomy and Right-Liver Graft Implantation......Page 98
Postoperative Care of the Donor......Page 100
Postoperative Management of the Recipient......Page 101
Donor Complications and Outcome......Page 102
Recipient Outcome......Page 103
Impact of LDLT......Page 104
References......Page 105
Introduction......Page 112
Living-Donor Islet Transplants......Page 114
Living-Donor Segmental Pancreas Transplants......Page 117
Perspectives......Page 121
References......Page 124
Introduction......Page 136
Indications......Page 138
Donor Evaluation......Page 140
Recipient Evaluation......Page 142
Donor operation......Page 143
Recipient operation......Page 145
Immunosuppression......Page 147
Maintaining fluid and electrolyte homeostasis......Page 148
Assessment of graft function......Page 149
Postoperative Complications and Management......Page 150
Infection......Page 152
Graft loss and re-transplantation......Page 153
Report from the United Network of Organ Sharing (UNOS) and the Intestinal Transplant Registry (ITR)......Page 154
Conclusions......Page 155
References......Page 156
Introduction......Page 160
Evaluation and Selection in the Donor......Page 161
Size Matching......Page 162
Surgical Technique in the Donor......Page 163
Surgical Technique in the Recipient......Page 166
Complications in the Donor......Page 168
Complications in the Recipient......Page 169
Detection and Management of Acute Rejection......Page 170
Results After Living-Donor Lobar Lung Transplantation......Page 173
Conclusion......Page 176
References......Page 177
Historical background......Page 180
The Role of HLA in HSCT......Page 183
Sources and Procurement of Allogeneic Haematopoietic Stem Cells......Page 186
Principles of Conditioning Regimens......Page 188
Early Complications After HSCT......Page 192
Graft versus Host Disease......Page 195
Immune Reconstitution After HSCT......Page 200
Infections After HSCT......Page 202
Bacterial infections......Page 203
Viral infections......Page 204
Other infections......Page 206
Results in children......Page 207
Results in adults......Page 212
Final Considerations......Page 215
References......Page 216
Index......Page 226