Lithium Effects on Granulopoiesis and Immune Function

Front Matter....Pages i-xiv
Lithium Carbonate in Medicine and Psychiatry....Pages 1-13
Biology of the Lithium Ion....Pages 15-59
Release of Vitamin Binding Proteins from Granulocytes by Lithium: Vitamin B 12 and Folate Binding Proteins....Pages 61-78
The Effect of Lithium on Release of Granulocyte Colony Stimulating Activity in Vitro ....Pages 79-86
The Effect of Lithium Upon Granulocyte Production in vitro and in vivo in the Mouse....Pages 87-98
Effect of Lithium on Colony Formation and Production of Colony-Stimulating Factor....Pages 99-109
Myelopoietic Modulation by Lithium: in vitro Experiments on its Mechanisms of Action in Man....Pages 111-126
Oral Lithium Carbonate Increases Colony Stimulating Activity Production from Human Mononuclear Cells....Pages 127-136
Effects of Lithium Chloride on Human and Murine Marrow Myeloid Colony Formation and Colony Stimulating Activity....Pages 137-144
Lithium Effects on Granulopoiesis in Mice Following Cytotoxic Chemotherapy....Pages 145-154
Lithium Carbonate Enhances Granulopoiesis and Attenuates Cyclophosphamide-Induced Injury in the Dog....Pages 155-166
Lithium Treatment of Cyclic Hematopoiesis in the Gray Collie....Pages 167-173
Clinical Investigation of Lithium Therapy in Acute Leukemia....Pages 175-186
Lithium and Granulocytopenia During Induction Therapy of Acute Myelogenous Leukemia: Update of an Ongoing Trial....Pages 187-197
A Placebo Controlled Study of a Seven Day Course of Lithium Carbonate Following Myelotoxic Chemotherapy....Pages 199-205
The Effect of Lithium Carbonate Administration in Patients with Advanced Small Cell Bronchogenic Carcinoma Receiving Combination Chemotherapy and Radiotherapy....Pages 207-229
Higher Leukocyte Nadirs with Lithium Carbonate After Chemotherapy....Pages 231-243
Prevention by Using Lithium Carbonate of Neutropenia Due to Antiblastics....Pages 245-255
A Seven Year Laboratory and Clinical Experience with Lithium Carbonate as an Adjuvant to Cancer Chemotherapy....Pages 257-274
Lithium Attenuation of Chemotherapy-Induced Granulocytopenia: Statistical and Clinical Significance?....Pages 275-279
In vivo and in vitro Effects of Lithium on Granulopoiesis in Human Neutropenic Disorders....Pages 281-291
Stimulation of Granulopoiesis in vitro and in vivo Using Lithium in Children with Chronic Neutropenia....Pages 293-304
Clinical Experience with Lithium in Aplastic Anemia and Congenital Neutropenia....Pages 305-320
Lithium Therapy of Chronic Neutropenia....Pages 321-332
Lithium Carbonate Therapy of Aplastic Anemia....Pages 333-333
Granulocyte Function in Patients Receiving Lithium Carbonate....Pages 335-346
Inhibition of Granulocyte Adherence by Lithium: Possible Relationship to Lithium-Induced Leukocytosis....Pages 347-355
Effects of Lithium on Polymorphonuclear Leukocyte Chemotaxis....Pages 357-370
Effects of Lithium on Neutrophil Metabolism in vitro and on Neutrophil Function During Therapy....Pages 371-388
The Bactericidal Defect of Neutrophil Function with Lithium Therapy....Pages 389-399
Effect of Lithium on Acute Myelocytic Leukemia Cells in Tissue Culture — a Preliminary Study....Pages 401-409
Drinking Water Lithium Levels Fail to Predict for the Incidences of Acute or Chronic Granulocytic Leukemia....Pages 411-416
Adjuvant-Like Effects of Lithium on Peripheral Blood Mononuclear Cells....Pages 417-427
Characterization of Lithium Effects on Two Aspects of T-Cell Function....Pages 429-446
Anti-Suppressor Cell Effects of Lithium in vitro and in vivo ....Pages 447-462
Lithium and Immune Function in Man....Pages 463-469
Back Matter....Pages 471-475