Leptin and Leptin Antagonists

TITLE PAGE......Page 2
Copyright ©2009 Landes Bioscience......Page 3
DEDICATION......Page 4
About the Editor... ARIEH GERTLER......Page 6
CONTENTS......Page 8
EDITOR AND CONTRIBUTORS......Page 12
PREFACE......Page 16
CHAPTER 1. Leptin Signal Transduction—A 2009 Update......Page 20
CHAPTER 2. Insights in the Activated LR Complex and the Rational Design of Antagonists......Page 34
CHAPTER 3. Study of Leptin: Leptin Receptor Interaction by FRET and BRET......Page 49
CHAPTER 4. Is Leptin a Pro- or Anti-Apoptotic Agent?......Page 62
CHAPTER 5. Leptin Actions in the Gastrointestinal Tract......Page 73
CHAPTER 6. Leptin as a Novel Marker in Breast and Colorectal Cancer......Page 82
CHAPTER 7. The Role of Leptin in Cardiac Physiology and Pathophysiology......Page 92
CHAPTER 8. The Role of Leptin in Bone Development and Growth......Page 102
CHAPTER 9. Involvement of Leptin in Arterial Hypertension......Page 110
CHAPTER 10. Involvement of Leptin in the Endometrial Function......Page 127
CHAPTER 11. The Use of Leptin for the Treatment of Lipodystrophy......Page 135
CHAPTER 12. Use of Anti-Leptin or Anti-Leptin Receptor Antibodies as Blockers of Immune Response......Page 145
CHAPTER 13. Use of Leptin Antagonists as Anti-Inflammatory and Anti-Fibrotic Reagents......Page 152
CHAPTER 14. The Role of Leptin during Early Life in Imprinting Later Metabolic Responses......Page 160
A-E......Page 182
F-M......Page 183
N-V......Page 184