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ویرایش: 1 نویسندگان: M. Reza Dana, Pedram Hamrah (auth.), David A. Sullivan, Michael E. Stern, Kazuo Tsubota, Darlene A. Dartt, Rose M. Sullivan, B. Britt Bromberg (eds.) سری: Advances in Experimental Medicine and Biology 506 ISBN (شابک) : 9781461352082, 9781461507178 ناشر: Springer US سال نشر: 2002 تعداد صفحات: 620 زبان: English فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) حجم فایل: 38 مگابایت
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کلمات کلیدی مربوط به کتاب غدد لاکریما ، فیلم اشک و سندرم های خشکی چشم 3: علوم پایه و ارتباط بالینی قسمت B: چشم شناسی، زیست شناسی تکاملی، دامپزشکی، ایمونولوژی
در صورت تبدیل فایل کتاب Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3: Basic Science and Clinical Relevance Part B به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.
توجه داشته باشید کتاب غدد لاکریما ، فیلم اشک و سندرم های خشکی چشم 3: علوم پایه و ارتباط بالینی قسمت B نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
در طول چندین دهه گذشته، تلاش های تحقیقاتی بین المللی قابل توجهی به سمت درک ترکیب و تنظیم لایه اشک پیش چشمی انجام شده است. انگیزه این تلاش این است که بدانیم لایه اشکی نقش مهمی در حفظ یکپارچگی قرنیه و ملتحمه، محافظت در برابر چالش میکروبی و حفظ حدت بینایی دارد. علاوه بر این، تحقیقات با این دانش تحریک شده است که تغییر یا کمبود لایه اشکی، که در افراد زیادی در سراسر جهان رخ می دهد، ممکن است منجر به خشک شدن سطح چشم، زخم و سوراخ شدن قرنیه، افزایش بروز بیماری های عفونی شود. و ناتوانی بینایی و نابینایی به طور بالقوه تلفظ می شود.
During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.
Front Matter....Pages i-iv
Front Matter....Pages v-v
Role of Immunity and Inflammation in Corneal and Ocular Surface Disease Associated with Dry Eye....Pages 729-738
Dry eye and Delayed Tear Clearance: “A Call to Arms”....Pages 739-743
Innate Immunity in the Cornea: A Putative Role for Keratocytes in the Chemokine Response to Viral Infection of the Human Corneal Stroma....Pages 745-751
The Role of ICAM-1 as a Signal Protein for Predisposition of Ocular Surface Inflammation....Pages 753-759
Flow Cytometric Analysis of the Inflammatory Marker HLA DR in Dry Eye Syndrome: Results from 12 Months of Randomized Treatment with Topical Cyclosporin A....Pages 761-769
Pathogenesis of Autoimmune Lacrimal Gland Disease in MRL/MPJ Mice....Pages 771-776
ICAM-1: Its Role in the Pathophysiology of Immune Activation in the MRL/LPR Mouse....Pages 777-781
Proinflammatory Cytokine Inhibition of Lacrimal Gland Secretion....Pages 783-787
Effect of Anti-Inflammatory Cytokines on the Activation of Lymphocytes by Lacrimal Gland Acinar Cells in an Autologous Mixed Cell Reaction....Pages 789-794
IL-2 Immunoreactive Proteins in Lacrimal Acinar Cells....Pages 795-799
Immunopathogenesis of Conjunctival Histopathologic Alteration in Non-Sjögren’s Keratoconjunctivitis Sicca....Pages 801-803
Topical Cyclosporine a (2%) Eyedrops in the Therapy of Atopic Keratoconjunctivitis and Keratoconjunctivitis Vernalis....Pages 805-812
Front Matter....Pages 813-813
Apoptosis: The Eyes Have It....Pages 815-820
Apoptosis in the Cornea in Response to Epithelial Injury: Significance to Wound Healing and Dry Eye....Pages 821-826
Mechanisms of Apoptosis in Human Corneal Epithelial Cells....Pages 827-834
A Functional Unit for Ocular Surface Immune Defense Formed by the Lacrimal Gland, Conjunctiva and Lacrimal Drainage System....Pages 835-844
Role of Tear Anti- Acanthamoeba IgA in Acanthamoeba Keratitis....Pages 845-850
Expression of Vascular Endothelial Growth Factor Receptor-3 (Vegfr-3) in the Conjunctiva-A Potential Link Between Lymphangiogenesis and Leukocyte Trafficking on the Ocular Surface....Pages 851-860
Human Lacrimal Drainage-Associated Lymphoid Tissue (LDALT) Belongs to the Common Mucosal Immune System....Pages 861-866
The Crypt System of the Human Conjunctiva....Pages 867-872
Front Matter....Pages 813-813
Organized Mucosa-Associated Lymphoid Tissue in Human Nasolacrimal Ducts....Pages 873-876
Front Matter....Pages 877-877
Contact Lenses and Tear Film Interactions....Pages 879-884
Effects of O 2 Transmissibility on Corneal Epithelium After Daily and Extended Contact Lens Wear in Rabbit and Man....Pages 885-893
Influence of the Tear Film Composition on Tear Film Structure and Symptomatology of Soft Contact Lens Wearers....Pages 895-899
Evaluation of the Pre-Lens Tear Film Forming on Three Disposable Contact Lenses....Pages 901-915
An Evaluation of Mucin Balls Associated with High-Dk Silicone-Hydrogel Contact Lens Wear....Pages 917-923
Cells Collected from the Corneal Surface in Sjögren’s Syndrome, Dry Eye, and Normals....Pages 925-928
The Thickness of the Post-Lens Tear Film Measured by Interferometry....Pages 929-933
Tear Lipid Composition of Hydrogel Contact Lens Wearers....Pages 935-938
Conjunctival Characteristics of Contact Lens Wearers and Nonwearers and Their Association with Symptomatology....Pages 939-943
Dry Eye Symptomatology of Contact Lens Wearers and Nonwearers....Pages 945-949
Contact Lens-Induced Papillary Conjunctivitis Is Associated With Increased Albumin Deposits On Extended Wear Hydrogel Lenses....Pages 951-955
Surface Protein Profile of Extended-Wear Silicon Hydrogel Lenses....Pages 957-960
The Detection of Kinin Activity in Contact Lens Wear....Pages 961-966
Immunoblotting and Tear Sampling Techniques for the Study of Contact Lens-Induced Variations in Tear Protein Profiles....Pages 967-971
Interaction between, the Contact Lens and the Ocular Surface....Pages 973-980
Clinical Benefits and Physical Properties of Addition of Hydroxypropyl Methylcellulose to a Multi-Purpose Contact Lens Care Solution....Pages 981-985
Front Matter....Pages 987-987
Epidemiology of Dry Eye Syndrome....Pages 989-998
Immunogenetics of Autoimmune Exocrinopathy in the Nod Mouse: More Than Meets the Eye....Pages 999-1007
Results of a Dry Eye Questionnaire from Optometric Practices in North America....Pages 1009-1016
Front Matter....Pages 987-987
The Effect of Hormone Replacement Therapy on the Symptoms and Physiologic Parameters of Dry Eye....Pages 1017-1022
Impaired Neurotransmission in Lacrimal and Salivary Glands of a Murine Model of Sjögren’s Syndrome....Pages 1023-1028
Menopause, Hormone Replacement Therapy and Tear Function....Pages 1029-1033
IDD3 and IDD5 Alleles From Nod Mice Mediate Sjögren’s Syndrome-Like Autoimmunity....Pages 1035-1039
Dry Eye Associated with Chronic Graft-Versus-Host Disease....Pages 1041-1045
Contribution of Neurogenic Inflammation to Irritable Eye Syndrome....Pages 1047-1050
Ocular Drying Associated with Oral Antihistamines (Loratadine) in the Normal Population-an Evaluation of Exaggerated Dose Effect....Pages 1051-1055
Evaluation of the Time to “Natural Compensation” in Normal and Dry Eye Subject Populations During Exposure to a Controlled Adverse Environment....Pages 1057-1063
Front Matter....Pages 1065-1065
Diagnosis and Treatment of the Dry Eye: A Clinical Perspective....Pages 1067-1078
Dry Eye Syndromes: Diagnosis, Clinical Trials and Pharmaceutical Treatment-‘Improving Clinical Trials’....Pages 1079-1086
Using Osmolarity to Diagnose Dry Eye: A Compartmental Hypothesis and Review of Our Assumptions....Pages 1087-1095
Reliability of Measurements of Tear Physiology....Pages 1097-1105
Use of Cevimeline, a Muscarinic Ml and M3 Agonist, in the Treatment of Sjögren’s Syndrome....Pages 1107-1116
Drug Development Issues in Pharmacological Treatments for Dry Eye....Pages 1117-1120
Alternative Reference Values for Tear Film Break up Time in Normal and Dry Eye Populations....Pages 1121-1125
Ocular Sensations and Symptoms Associated with Tear Break Up....Pages 1127-1133
Evaluation of the Akorn Dry Eye Test (Dettm) as a Predictor of Contact Lens Comfort....Pages 1135-1140
Predicting Optical Effects of Tear Film Break Up on Retinal Image Quality Using the Shack-Hartmann Aberrometer and Computational Optical Modeling....Pages 1141-1147
Improvement of Tear Stability Following Warm Compression in Patients with Meibomian Gland Dysfunction....Pages 1149-1152
An Evaporative Stress Test for Borderline Dry Eye Detection....Pages 1153-1157
Front Matter....Pages 1065-1065
Tear Production Measurement, Basal or Reflex Assessment?....Pages 1159-1163
Innovative Dry Eye Diagnosis System Using Microbalance Technology....Pages 1165-1169
The Repeatability of Diagnostic Tests and Surveys in Dry Eye....Pages 1171-1175
Association of Clinical Diagnostic Tests and Dry Eye Surveys: The Nei-Vfq-25 and the OSDI....Pages 1177-1181
Economic and Quality Of Life Impact of Dry Eye Symptoms in Women with Sjögren’s Syndrome....Pages 1183-1188
Patient-Reported Versus Doctor-Diagnosed Dry Eye: The Assessment of Symptoms....Pages 1189-1193
Keratoconjunctivitis Sicca Versus Dry Mouth and Autoantibodies in Primary and Secondary Sjögren’s Syndrome....Pages 1195-1199
Tear Spreading Rates: Post-Blink....Pages 1201-1204
Near Vision Accommodation in Horizontality with Vdt: Why Low Blinking and Dry Eye?....Pages 1205-1211
Analysis of Tear Protein Patterns for the Diagnosis of Dry Eye....Pages 1213-1216
The Significance of Salivary Gland Ultrasonography in the Diagnosis of Dry Eye Syndrome....Pages 1217-1220
The Effect of Nasal Mucosal Stimulation on Schirmer Tests in Sjögren’s Syndrome and Dry Eye Patients....Pages 1221-1226
A Simple Method of Detecting the Anti-Inflammatory Action of Topical Dry Eye Treatments....Pages 1227-1232
Efficacy of Sodium Hyaluronate Eye Drops of Different Osmolarities in the Symptomatic Treatment of Dry Eye Patients....Pages 1233-1235
Topical Non-Preserved Diclofenac Therapy for Keratoconjunctivitis Sicca....Pages 1237-1240
The Effect of Botulinum Toxin a Treatment on Tear Function Parameters and on the Ocular Surface....Pages 1241-1246
Efficacy of Autologous Serum Treatment in Patients with Severe Dry Eye....Pages 1247-1250
Ocular Safety of Ins365 Ophthalmic Solution, a P2y 2 Agonist, in Patients with Mild to Moderate Dry Eye Disease....Pages 1251-1257
Ocular Surface Reconstruction with Amniotic Membrane Transplantation in Chemical Burn....Pages 1259-1262
Surgical Reconstruction of the Tear Meniscus at the Lower Lid Margin for Treatment of Conjunctivochalasis....Pages 1263-1268
Front Matter....Pages 1065-1065
The Effect of Punctal Occlusion on Tear Lactoferrin in Aqueous Deficient Dry Eye Patients....Pages 1269-1271
Silicon Punctal Plug Insertion in the Treatment of Severe Dry Eye....Pages 1273-1276
Application of Atelocollagen Solution for Lacrimal Duct Occlusion....Pages 1277-1281
Atelocollagen Punctal Occlusion for the Treatment of the Dry Eye....Pages 1283-1284
Fiberscopic Observation of Canaliculi After Punctal Plug Extrusion....Pages 1285-1288
Front Matter....Pages 1289-1289
Neural Stem Cells for Cns Repair: State of the Art and Future Directions....Pages 1291-1296
Particle-Mediated Gene Transfer to Ocular Surface Epithelium....Pages 1297-1308
In Vivo Gene Transfer Into Corneal Epithelial Progenitor Cells By Viral Vectors....Pages 1309-1314
Gene Therapy for the Prevention of Corneal Haze after Photorefractive/Phototherapeutic Keratectomy Excimer Laser Surgery....Pages 1315-1321
Ex Vivo Preservation and Expansion of Human Limbal Epithelial Stem Cells on Amniotic Membrane for Treating Corneal Diseases with Total Limbal Stem Cell Deficiency....Pages 1323-1334
Corneal Blindness from End-Stage Sjögren’s Syndrome and Graft-Versus-Host Disease....Pages 1335-1338
Front Matter....Pages 1339-1339
Closing Address: The Academic Perspective....Pages 1341-1342
Industry Perspective....Pages 1343-1344
Addendum....Pages 1345-1348
Back Matter....Pages 1349-1385