Kinins—II: Biochemistry, Pathophysiology, and Clinical Aspects

Front Matter....Pages i-xii
Presentation of a Film on the “Central Effects of Bradykinin”....Pages 1-4
Front Matter....Pages 5-5
The New Vasoactive Peptides in Amphibian Skin....Pages 7-13
Specific Isolation of Biologically-Active Peptides by Means of Immobilized Anhydrotrypsin and Anhydrochymotrypsin....Pages 15-27
Comparative Study on Distribution of Bombesin-, Neurotensin- and α-Endorphin-Like Immunoreactivities in Canine Tissues....Pages 29-37
Preparation of Intrinsically-Labelled Kinins....Pages 39-50
Kininogenase Activity and Kinin-Like Substance in the Venomous Spicules and Spines of Lepidopteran Larvae....Pages 51-55
Front Matter....Pages 57-57
An Approach to the Chemical Quantitation of Kinins for the Assay of Kininogenases....Pages 59-65
Determination of Prekallikrein in Plasma by Means of a Chromogenic Tripeptide Substrate for Plasma Kallikrein....Pages 67-82
Methods for the Determination of Glandular Kallikrein by Means of a Chromogenic Tripeptide Substrate....Pages 83-95
A Direct Radioimmunoassay for Human Urinary Kallikrein....Pages 97-103
Estimation of Urinary Kininogenase Activity Using Bovine Serum Low Molecular Weight Kininogen....Pages 105-114
A Simple Radioassay for Human Urinary Kallikrein....Pages 115-125
Glandular Kallikrein in Plasma and Urine: Evaluation of a Direct RIA for Its Determination....Pages 127-142
Method for Measurement of Human Urinary Kininase Activity....Pages 143-145
Fluorogenic Peptide Substrates for Proteases in Blood Coagulation, Kallikrein-Kinin and Fibrinolysis Systems....Pages 147-163
Determination of Hageman Factor (HG, Factor XII) and Plasma Prekallikrein (Fletcher Factor) by Radioimmunoassays....Pages 165-172
Assay Methods for Prekallikrein and Kininogens and Their Applications....Pages 173-184
Synthetic Bradykinin-Like Peptides....Pages 185-193
Enzyme Immunoassay of Bradykinin....Pages 195-202
Assay of Angiotensin I by Fluorescence Polarization Method....Pages 203-211
Front Matter....Pages 57-57
A System for the Study of Kallikreins....Pages 213-218
Front Matter....Pages 219-219
Chemical Relations between Renal and Urinary Kallikrein of Rat....Pages 221-224
Radioimmunoassay of Rat Submandibular Gland Kallikrein and the Detection of Immunoreactive Antigen on Blood....Pages 225-234
Human Urinary Kallikrein — Biochemical and Physiological Aspects....Pages 235-244
The Primary Structure of Porcine Glandular Kallikreins....Pages 245-260
Substrate Specificity of Porcine Pancreatic Kallikrein....Pages 261-271
Purification and Characterization of Hog Pancreatic Kallikrein I, II and III....Pages 273-290
Rat Stomach Kallikrein: Its Purification and Properties....Pages 291-303
A Simple, Large Scale Process for Purifying Human Urinary Kallikrein, Based on Reverse Osmosis and Ammonium Sulfate Precipitation....Pages 305-312
Components of the Kallikrein-Kinin System in Urine....Pages 313-323
Purification of Horse Renal Kallikrein and Chemical Relations with Horse Urinary Kallikrein....Pages 325-333
Substrate Specificities of Acid Kininogenases....Pages 335-349
Some Properties of Acrosin, a Kininogenase from Sperm Acrosome....Pages 351-361
Studies on Kallikrein-Kinin System in Bovine Lung....Pages 363-372
Front Matter....Pages 373-373
How do Kinins Affect Vascular Tone?....Pages 375-391
Effect of Bradykinin to Cyclic AMP Levels and Response of Murine Lymphocytes....Pages 393-407
Nechanism of Substance P-Induced Salivary Secretion in Rats....Pages 409-420
Immunopharmacological Study of Forssman Shock in Guinea Pigs....Pages 421-424
Significance of Adrenergic α-Effect on Salivary Kallikrein Secretion in the Submandibular Gland of the Dog....Pages 425-437
Localization of Glandular Kallikreins and Secretion of Kallikrein from the Major Salivary Glands of the Rat....Pages 439-450
Front Matter....Pages 373-373
Possible Relationship between Salivary Kallikrein and Water-Na-K Secretion Stimulated by Tityustoxin (TsTx)....Pages 451-459
Effect of Kallikrein-Kinin System on Ion Transport Across Rat Small Intestine....Pages 461-471
Pulmonary Anaphylaxis and the Kallikrein-Kinin System....Pages 473-486
Studies on the Effects of Bradykinin and Its Fragments on the Central Nervous System....Pages 487-497
Front Matter....Pages 499-499
Kallikrein System during Treatment of Hematological Malignancies....Pages 501-509
Possible Involvement of Kinins and Prostaglandins in the Translation of Insulin Action on Glucose Uptake into Skeletal Muscle....Pages 511-520
The Interaction of Kallikrein with Urokinase in Peripheral Circulatory Disorders. A Microcirculatory Observation....Pages 521-528
Kallikrein Treatment of Male Infertility....Pages 529-536
Determination of Various Semen Parameters and Sex Hormone Levels in Subfertile Men during Kallikrein Therapy....Pages 537-546
Metabolic Changes after Application of Kallikrein in an Ergometrical Test....Pages 547-553
Participation of Kallikrein, Coagulation/Fibrinolysis Parameters in the Development of Glomerulonephritis....Pages 555-567
Improvement of Glucose Assimilation and Protein Degradation by Bradykinin in Maturity Onset Diabetics and in Surgical Patients....Pages 569-576
Autoreversal of Bradykinin Response in the Perfused Isolated Canine Hind Limb....Pages 577-586
Dynamics of Kallikreinogen under Hemodialysis....Pages 587-601
Altered Urinary Excretion of Human Kininase Activity in Acute Myocardial Infarction....Pages 603-606
Back Matter....Pages 607-610