Isoprenoid Synthesis in Plants and Microorganisms: New Concepts and Experimental Approaches

Front Matter....Pages i-xix
Isoprenoid Biosynthesis in Prokaryotic Organisms....Pages 1-16
1-Deoxy- d -Xylulose 5-Phosphate Synthase (DXS), a Crucial Enzyme for Isoprenoids Biosynthesis....Pages 17-28
Biosynthetic Genes and Enzymes of Isoprenoids Produced by Actinomycetes....Pages 29-49
Interactions of Isoprenoid Pathway Enzymes and Indirect Stimulation of Isoprenoid Biosynthesis by Pentose Phosphate Cycle Substrates in Synechocystis PCC 6803....Pages 51-63
Metabolic Engineering of Monoterpenoid Production in Yeast....Pages 65-71
Metabolic Engineering of Isoprenoid Production: Reconstruction of Multistep Heterologous Pathways in Tractable Hosts....Pages 73-89
Microbially Derived Semisynthetic Artemisinin....Pages 91-106
Artemisinin: Controlling Its Production in Artemisia annua ....Pages 107-117
Fosmidomycin as an Antimalarial Agent....Pages 119-137
Regulation of Isoprene and Monoterpene Emission....Pages 139-153
Involvement of Compartmentalization in Monoterpene and Sesquiterpene Biosynthesis in Plants....Pages 155-169
Strategies for the Manipulation of Carbocations by Aristolochene Synthase....Pages 171-183
Elucidating the Formation of Geranyllinalool, the Precursor of the Volatile C 16 -Homoterpene TMTT Involved in Indirect Plant Defense....Pages 185-198
Strigolactones: A Cry for Help Results in Fatal Attraction. Is Escape Possible?....Pages 199-211
Prenyldiphosphate Synthases and Gibberellin Biosynthesis....Pages 213-232
Gibberellin Phytohormone Metabolism....Pages 233-249
Control of Plastidial Isoprenoid Precursor Supply: Divergent 1-Deoxy- d -Xylulose 5-Phosphate Synthase ( DXS ) Isogenes Regulate the Allocation to Primary or Secondary Metabolism....Pages 251-270
Tobacco Trichomes as a Platform for Terpenoid Biosynthesis Engineering....Pages 271-283
Prenylated Proteins Are Required for Methyl-Jasmonate-Induced Monoterpenoid Indole Alkaloids Biosynthesis in Catharanthus roseus ....Pages 285-296
The Role of Prenylcysteine Methylation and Metabolism in Abscisic Acid Signaling in Arabidopsis thaliana ....Pages 297-306
What We Do and Do Not Know About the Cellular Functions of Polyisoprenoids....Pages 307-313
Regulation of 3-Hydroxy-3-Methylglutaryl-CoA Synthase and 3-Hydroxy-3-Methylglutaryl-CoA Reductase and Rubber Biosynthesis of Hevea brasiliensis (B.H.K.) Mull. Arg....Pages 315-327
Development of Crops to Produce Industrially Useful Natural Rubber....Pages 329-345
Occurrence of Two Acetoacetyl-Coenzyme A Thiolases with Distinct Expression Patterns and Subcellular Localization in Tobacco....Pages 347-365
The Sterol C4-Demethylation in Higher Plants....Pages 367-380
Sterol C22-Desaturase and Its Biological Roles....Pages 381-391
Enzymatic Synthesis of Unnatural Cyclic Triterpenes....Pages 393-403
Saponin Synthesis and Function....Pages 405-424
Cardenolide Aglycone Formation in Digitalis ....Pages 425-438
Biosynthesis of Isoprenoid Precursors in Arabidopsis....Pages 439-456
Understanding the Mechanisms that Modulate the MEP Pathway in Higher Plants....Pages 457-464
Functional Analysis of HMG-CoA Reductase and Oxidosqualene Cyclases in Arabidopsis ....Pages 465-474
Systems Understanding of Isoprenoid Pathway Regulation in Arabidopsis ....Pages 475-491
Back Matter....Pages 493-505