Investigations of Early Nutrition Effects on Long-Term Health: Methods and Applications

Front Matter ....Pages i-xiv
Front Matter ....Pages 1-1
 Nutritional Programming Effects on Development of Metabolic Disorders in Later Life  (Thomas Prates Ong, Paul C. Guest)....Pages 3-17
 Effects of Prenatal Nutrition and the Role of the Placenta in Health and Disease  (Leslie Myatt, Kent L. Thornburg)....Pages 19-46
 Developmental Origins of Stress and Psychiatric Disorders  (Francesca L. Guest, Paul C. Guest)....Pages 47-58
 Proteomic Studies of Psychiatric Disorders  (Paul C. Guest)....Pages 59-89
 Developmental Origins of Breast Cancer: A Paternal Perspective  (Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, Thomas Prates Ong)....Pages 91-103
 Point-of-Care Testing and Personalized Medicine for Metabolic Disorders  (Francesca L. Guest, Paul C. Guest)....Pages 105-114
 Pregnancy and Lactation: A Window of Opportunity to Improve Individual Health  (Guadalupe L. Rodríguez-González, Diana C. Castro-Rodríguez, Elena Zambrano)....Pages 115-144
 Utility of Small Animal Models of Developmental Programming  (Clare M. Reynolds, Mark H. Vickers)....Pages 145-163
Front Matter ....Pages 165-165
 Generation of Maternal Obesity Models in Studies of Developmental Programming in Rodents  (Paul D. Taylor, Phillippa A. Matthews, Imran Y. Khan, Douglas Rees, Nozomi Itani, Lucilla Poston)....Pages 167-199
 Generation of the Maternal Low-Protein Rat Model for Studies of Metabolic Disorders  (Dan Ma, Susan E. Ozanne, Paul C. Guest)....Pages 201-206
 Investigation of Paternal Programming of Breast Cancer Risk in Female Offspring in Rodent Models  (Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, Thomas Prates Ong)....Pages 207-220
 Studies of Isolated Peripheral Blood Cells as a Model of Immune Dysfunction  (Hassan Rahmoune, Paul C. Guest)....Pages 221-229
 Studies of a Neuronal Cell Line as a Model of Psychiatric Disorders  (Keiko Iwata)....Pages 231-238
 Assessment of Placental Transport Function in Studies of Disease Programming  (Amanda N. Sferruzzi-Perri)....Pages 239-250
 Assessment of Fatty Liver in Models of Disease Programming  (Kimberley D. Bruce, Karen R. Jonscher)....Pages 251-266
 Capillary Blood Sampling from the Finger  (Kieron Rooney)....Pages 267-272
 Physical Activity Assessment in Clinical Studies of Substance Use Disorder  (Rhiannon Dowla, Bridin Murnion, Kia Roberts, Jonathan Freeston, Kieron Rooney)....Pages 273-284
 Cardiopulmonary Exercise Testing  (Derek Tran)....Pages 285-295
 Cardiovascular Assessment in Human Research  (Marjan Mosalman Haghighi, Julian Ayer)....Pages 297-310
 Nutritional Programming Effects on the Immune System  (Donald B. Palmer)....Pages 311-319
 Small RNA Sequencing: A Technique for miRNA Profiling  (Lucas Carminatti Pantaleão, Susan E. Ozanne)....Pages 321-330
 Pulse-Chase Biosynthetic Radiolabeling of Pancreatic Islets to Measure Beta Cell Function  (Paul C. Guest)....Pages 331-341
 Rapid and Easy Protocol for Quantification of Next-Generation Sequencing Libraries  (Steve F. C. Hawkins, Paul C. Guest)....Pages 343-350
 Telomere Length Analysis: A Tool for Dissecting Aging Mechanisms in Developmental Programming  (Jane L. Tarry-Adkins, Susan E. Ozanne)....Pages 351-363
 Qualitative and Quantitative NMR Approaches in Blood Serum Lipidomics  (Banny Silva Barbosa, Lucas Gelain Martins, Tássia B. B. C. Costa, Guilherme Cruz, Ljubica Tasic)....Pages 365-379
 In Vivo Electrical Stimulation for the Assessment of Skeletal Muscle Contractile Function in Murine Models  (Kaio F. Vitzel, Marco A. Fortes, Gabriel Nasri Marzuca-Nassr, Maria V. M. Scervino, Carlos H. Pinheiro, Leonardo R. Silveira et al.)....Pages 381-395
 Experimental Model of Skeletal Muscle Laceration in Rats  (Phablo Abreu, Gabriel Nasri Marzuca-Nassr, Sandro Massao Hirabara, Rui Curi)....Pages 397-401
 Neuropsychiatric Sequelae of Early Nutritional Modifications: A Beginner’s Guide to Behavioral Analysis  (Ann-Katrin Kraeuter, Paul C. Guest, Zoltán Sarnyai)....Pages 403-420
 Hyperlocomotion Test for Assessing Behavioral Disorders  (Dan Ma, Paul C. Guest)....Pages 421-425
 2D-DIGE Analysis of Eye Lens Proteins as a Measure of Cataract Formation  (Paul C. Guest)....Pages 427-437
 Mass Spectrometry Profiling of Pituitary Glands  (Divya Krishnamurthy, Hassan Rahmoune, Paul C. Guest)....Pages 439-447
 Multiplex Immunoassay Profiling of Hormones Involved in Metabolic Regulation  (Laurie Stephen, Paul C. Guest)....Pages 449-456
 Time-Resolved Fluorescence Assays for Quantification of Insulin Precursors in Plasma and Serum  (Kevin Taylor, Ian Halsall, Paul C. Guest, Keith Burling)....Pages 457-465
 Identification of Neural Stem Cell Biomarkers by Isobaric Tagging for Relative and Absolute Quantitation (iTRAQ) Mass Spectrometry  (Paul C. Guest)....Pages 467-476
 Lab-on-a-Chip Device for Rapid Measurement of Vitamin D Levels  (Harald Peter, Nikitas Bistolas, Soeren Schumacher, Cecilia Laurisch, Paul C. Guest, Ulrich Höller et al.)....Pages 477-486
 Kidney Smartphone Diagnostics  (P. R. Matías-García, J. L. Martinez-Hurtado)....Pages 487-498
 A User-Friendly App for Blood Coagulation Disorders  (Johannes Vegt, Paul C. Guest)....Pages 499-504
 Hormonal Smartphone Diagnostics  (P. R. Matías-García, J. L. Martinez-Hurtado, A. Beckley, M. Schmidmayr, V. Seifert-Klauss)....Pages 505-515
Back Matter ....Pages 517-520