Intracranial Pressure and Brain Biochemical Monitoring

Front Matter....Pages I-XIII
Front Matter....Pages 1-1
How to Select Patients with Normal Pressure Hydrocephalus for Shunting....Pages 3-5
Agreement Between CSF Flow Dynamics in MRI and ICP Monitoring in the Diagnosis of Normal Pressure Hydrocephalus. Sensitivity and Specificity of CSF Dynamics to Predict Outcome....Pages 7-10
Shunting to the Sagittal Sinus....Pages 11-14
Why Valve Opening Pressure Plays a Relatively Minor Role in the Postural ICP Response to Ventricular Shunts in Normal Pressure Hydrocephalus: Modeling and Implications....Pages 15-17
Dynamic Shunt Testing Applying Short Lasting Pressure Waves — Inertia of Shunt Systems....Pages 19-21
Factors Determining Mean ICP in Hydrocephalic Patients with Hakim-programmable Valve: Implications of the Parallel Arrangement of the CSF Outflow Resistance and Shunt....Pages 23-26
Shunt Testing in-Vivo: A Method Based on the Data from the UK Shunt Evaluation Laboratory....Pages 27-30
Compensatory Mechanisms in Patients with Benign Intracranial Hypertension Syndrome....Pages 31-33
Intracranial Hypertension after Surgery in Patients with Chiari I Malformation and Normal or Moderate Increase in Ventricular Size....Pages 35-38
The Role of Cerebral Blood Flow and Cerebrovascular Reserve Capacity in the Diagnosis of Chronic Hydrocephalus — a PET-Study on 60 Patients....Pages 39-41
PET-Studies in Idiopathic Chronic Hydrocephalus before and after Shunt-Treatment: The Role of Risk Factors for Cerebrovascular Disease (CVD) on Cerebral Hemodynamics....Pages 43-45
Regional Cerebral Blood Flow Profiles of Shunt-Responder in Idiopathic Chronic Hydrocephalus — A 15-O-Water PET-Study....Pages 47-49
Neuropsychological Testing to Improve Surgical Management of Patients with Chronic Hydrocephalus after Shunt Treatment....Pages 51-53
Neuropsychological Sequels to Changes in Global Cerebral Blood Flow and Cerebrovascular Reserve Capacity after Shunt Treatment in Chronic Hydrocephalus — A Quantitative PET-Study....Pages 55-57
Communicating Hydrocephalus: The Biomechanics of Progressive Ventricular Enlargement Revisited....Pages 59-63
Front Matter....Pages 65-65
Is CPP Therapy Beneficial for all Patients with High ICP?....Pages 67-68
Metabolic Suppressive Therapy as a Treatment for Intracranial Hypertension–Why it Works and when it Fails....Pages 69-70
Can Hyperventilation Improve Cerebral Microcirculation in Patients with High ICP?....Pages 71-72
Cerebral Perfusion Pressure and Spect in Patients after Craniocerebral Injury with Transtentorial Herniation....Pages 73-75
Decompressive Craniectomy Following Traumatic Brain Injury: ICP, CPP and Neurological Outcome....Pages 77-79
Front Matter....Pages 65-65
Evolving Lesions in Traumatic Subarachnoid Hemorrhage: Prospective Study of 110 Patients with Emphasis on the Role of ICP Monitoring....Pages 81-82
Effect of Early Induction of Hypothermia on Severe Head Injury....Pages 83-84
Significance of Temperature Difference Between Cerebral Cortex and Axilla in Patients Under Hypothermia Management....Pages 85-87
ICP is Lower During Propofol Anaesthesia Compared to Isoflurane and Sevoflurane....Pages 89-91
Effects of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Perfusion Pressure....Pages 93-97
The Safety of the Open Lung Approach in Neurosurgical Patients....Pages 99-101
Optimizing Cerebral Perfusion Pressure During Fiberoptic Bronchoscopy in Severe Head Injury: Effect of Hyperventilation....Pages 103-105
Front Matter....Pages 107-107
ICP and CBF Regulation: Effect of the Decompressive Craniectomy....Pages 109-111
ICP and CBF Regulation: A new Hypothesis to Explain the “Windkessel” Phenomenon....Pages 113-116
Clinical Significance of Cerebral Autoregulation....Pages 117-119
Routine Utilization of the Transient Hyperaemic Response Test after Aneurysmal Subarachnoid Haemorrhage....Pages 121-124
Is Transcranial Doppler Ultrasonography (TCD) Good Enough in Determining CO 2 Reactivity and Pressure Autoregulation in Head-Injured Patients?....Pages 125-127
Comparison Between two Static Autoregulation Evaluation Methods....Pages 129-132
Asymmetry of Cerebral Autoregulation Following Head Injury....Pages 133-134
Oscillations in the Near-Infrared Signal in Patients with Severe Head Injury....Pages 135-137
Slow Rhythmic Oscillations in Intracranial CSF and Blood Flow: Registered by MRI....Pages 139-142
Cyclic Variation of Cerebral Pial Arteriolar Diameter Synchronized with Positive—Pressure Inhalation....Pages 143-145
Spectral Characteristics of B-Waves and Other Low-Frequency Activity....Pages 147-150
Variation of Proposed Correlation Indices of Cerebrovascular Reactivity with Change of Arteriolar Diameter....Pages 151-153
Use of Resistance-Area Product Derived from Doppler MCA Velocity to Estimate the Range of Active Cerebrovascular Regulation....Pages 155-157
Front Matter....Pages 159-159
Online Analysis of Intracranial Pressure Waves....Pages 161-162
Information Technology and CPP Management in Neuro Intensive Care....Pages 163-165
Multi-Centre Assessment of the Spiegelberg Compliance Monitor: Interim Results....Pages 167-170
Clinical Experience in the use of the Spiegelberg Automated Compliance Device in the Assessment of Patients with Hydrocephalus....Pages 171-172
Continuous Cerebral Compliance Monitoring in Severe Head Injury: Its Relationship with Intracranial Pressure and Cerebral Perfusion Pressure....Pages 173-175
Intracranial Compliance as a Bed-Side Monitoring Technique in Severely Head-Injured Patients....Pages 177-180
An Experimental Evaluation of a new Intraparenchymal Continuous Compliance Probe: Preliminary Studies....Pages 181-182
An Estimated Compliance Index Derived from Intracranial Pressure Recording....Pages 183-185
Non-Invasive Assessment of Intracranial Compliance Using a new 2-D “Transit Time” vs “Frequency Centroid” Map....Pages 187-190
Front Matter....Pages 191-191
Approximate Entropy: A Regularity Statistic for Assessment of Intracranial Pressure....Pages 193-195
Simultaneous Measurement of Local Cortical Blood Flow and Tissue Oxygen Saturation by Near Infra-Red Laser Doppler Flowmetry and Remission Spectroscopy in the Pig Brain....Pages 197-199
Cerebral Veno-Arterial pCO2 Difference as an Estimator of Uncompensated Cerebral Hypoperfusion....Pages 201-204
Glial and Neuronal Serum Markers after Controlled Cortical Impact Injury in the Rat....Pages 205-207
Long-Time in-Vivo Metabolic Monitoring Following Experimental Brain Contusion Using Proton Magnetic Resonance Spectroscopy....Pages 209-212
Determination of Contusion and Oedema Volume by MRI Corresponds to Changes of Brain Water Content Following Controlled Cortical Impact Injury....Pages 213-215
Secondary Insults Worsen Blood Brain Barrier Dysfunction Assessed by MRI in Cerebral Contusion....Pages 217-219
Neuronal Activity Determined by Quantitative EEG and Cortical Microdialysis is Increased Following Controlled Cortical Impact Injury in Rats....Pages 221-223
Norepinephrine is Superior to Dopamine in Increasing Cortical Perfusion Following Controlled Cortical Impact Injury in Rats....Pages 225-227
Cortical Hypoperfusion Precedes Hyperperfusion Following Controlled Cortical Impact Injury....Pages 229-231
Effects of Brain Hypothermia on Brain Edema Formation after Intracerebral Hemorrhage in Rats....Pages 233-235
Front Matter....Pages 191-191
Appropriate Cerebral Perfusion Pressure During Rewarming after Therapeutic Hypothermia....Pages 237-239
Diffuse Brain Injury Complicated by Acute Subdural Hematoma and Secondary Insults in the Rodents: The Effect of Surgical Evacuation....Pages 241-242
Diffuse Brain Injury Complicated by Acute Subdural Hematoma in the Rodents: The Effect of Early or Delayed Surgical Evacuation....Pages 243-244
Traumatic Subarachnoidal Hemorrhage in the Developing Rat....Pages 245-247
Experimental Intracerebral Hemorrhage Effect of Lysed Erythrocytes on Brain Edema and Blood-Brain Barrier Permeability....Pages 249-251
Brain Edema after Intracerebral Hemorrhage: The Effects of Systemic Complement Depletion....Pages 253-256
Metabolic Alterations in Cerebrospinal Fluid from Double Hemorrhage Model of Dogs....Pages 257-263
Effect of Ischemic Preconditioning on Edema Formation and Cerebrovascular Injury Following Focal Cerebral Ischemia....Pages 265-268
ICP Monitoring Following Bilateral Carotid Occlusion in GFAP-Null Mice....Pages 269-270
Spinal Cerebrospinal Fluid Pathways and their Significance for the Compensation of Kaolin-Hydrocephalus....Pages 271-273
Temporal and Regional Profile of Neuronal and Glial Cellular Injury after Induction of Kaolin Hydrocephalus....Pages 275-277
Front Matter....Pages 279-279
Mechanisms of the Mass Effect of Cerebral Contusion: ICP Monitoring and Diffusion MRI Study....Pages 281-283
Incidence of Intracranial Hypertension Related to Jugular Bulb Oxygen Saturation Disturbances in Severe Traumatic Brain Injury Patients....Pages 285-287
Detection of Early Ischemia in Severe Head Injury by Means of Arteriovenous Lactate Differences and Jugular Bulb Oxygen Saturation, Relationship with CPP, Severity Indexes and Outcome. Preliminary Analysis....Pages 289-293
Non Invasive Local Cerebral Oxygenation Monitoring Using a Combination of Light and Ultrasound....Pages 295-297
Brain Tissue PO 2 : Correlation with Cerebral Blood Flow....Pages 299-301
Coexistence of Regional Cerebral Hypoxia with Normal or Hyperemic Brain Detected by Global Monitoring Methods. Analysis of Apparently Contradictory Findings Based on the Siggaard-Andersen Model of Tissue Hypoxia....Pages 303-305
Therapeutic Aspects of Brain Tissue pO 2 Monitoring after Subarachnoid Hemorrhage....Pages 307-309
Dynamic Correlation Between Tissue PO2 and near Infrared Spectroscopy....Pages 311-313
Effects of Hyperoxia on Brain Tissue Oxygen Tension in Cerebral Focal Lesions....Pages 315-317
Front Matter....Pages 279-279
Detection of Secondary Insults by Brain Tissue pO 2 and Bedside Microdialysis in Severe Head Injury....Pages 319-321
Intraoperative Monitoring of Brain Tissue Oxygen and Carbon Dioxide Pressure in Peritumoural Oedema by Stereotactic Placement of Multiparameter Microsensors....Pages 323-325
Effects of Variation in Cerebral Haemodynamics During Aneurysm Surgery on Brain Tissue Oxygen and Metabolism....Pages 327-329
Microdialysate Nitrate/Nitrite Levels Following Severe Head Injury....Pages 331-333
Neurochemical Changes in Ventilated Head-Injured Patients with Cerebral Perfusion Pressure Treatment Failure....Pages 335-338
Front Matter....Pages 339-339
Third International Satellite Conference on Neuro-Chemical Monitoring....Pages 341-342
Measurement of the Nitric Oxide Metabolites Nitrate and Nitrite in the Human Brain by Microdialysis....Pages 343-345
Comparison of Microdialysate Arginine and Glutamate Levels in Severely Head-Injured Patient....Pages 347-349
Temporal Profiles of Extracellular Nitric Oxide Metabolites Following Aneurysmal Subarachnoid Hemorrhage....Pages 351-354
Delayed Increase in Extracellular Glycerol with Post–Traumatic Electrographic Epileptic Activity: Support for the Theory that Seizures Induce Secondary Injury....Pages 355-357
Clinical Cerebral Microdialysis — Determining the True Extracellular Concentration....Pages 359-362
Extracellular Lactate/Pyruvate and Glutamate Changes in Patients During Per-operative Episodes of Cerebral Ischaemia....Pages 363-365
The Evaluation of Brain CBF and Mitochondrial Function by a Fiber Optic Tissue Spectroscope in Neurosurgical Patients....Pages 367-371
Application of Chemical Shift Imaging for Measurement of NAA in Head Injured Patients....Pages 373-375
Investigation of Extracellular Amino Acid Release in Children with Severe Head Injury Using Microdialysis. A Pilot Study....Pages 377-379
Back Matter....Pages 381-384