Intracellular Protein Catabolism II

Front Matter....Pages i-xv
Intracellular Protein Catabolism in Vitro and in Vivo....Pages 1-11
An Energy Requirement for Intralysosomal Proteolysis in Phagolysosomes and Tissue Slices....Pages 12-26
Inhibition of Cell Protein Degradation by Microtubular Inhibitors....Pages 27-42
Increased Degradation Rates of Canavanine-Containing Proteins in Hepatoma Cells....Pages 43-48
Studies of the Degradation of Proteins in Animal and Bacterial Cells....Pages 49-66
Protein Degradation in Neurospora Crassa....Pages 67-72
Studies on the Mechanism of Endocytosis in Fibroblasts with the use of Specific Antibodies....Pages 73-84
Specificity of Breakdown Based on the Inactivation of Active Proteins and Peptides by Brain Proteolytic Enzymes....Pages 85-102
Determination of the Average Degradation Rate of Mixtures of Protein....Pages 103-107
Primary Reaction of Intracellular Protein Catabolism....Pages 108-110
Degradation of Abnormal Proteins in Escherichia Coli: In Vitro Proteolysis of Cyanogen Bromide Peptides....Pages 111-115
Degredation of Abnormal Proteins in Escherichia Coli — Susceptibility of CNBr Generated Peptides from Alkaline Phosphatase to Proteolysis in E. Coli Cell Extracts....Pages 116-121
Changes in Metabolic Stability of Structural and Enzyme Proteins in Experimental Hepatomegaly....Pages 122-126
Subcellular Compartmentation and Degradation of Insulin in Liver at the Outset of Hypoglycaemia Induced by Oral Antidiabetic Sulphanylureas....Pages 127-130
Degradation of Insulin and Glucagon in Homogenates and Subcellular Fractions of Isolated Pancreatic Islets....Pages 131-138
Heterogeneity of Rat Liver Lysosomes with Respect to Proteolytic Activity at pH 6.0....Pages 139-143
The Age Dependence of Intracellular Proteolysis in the Rat Liver....Pages 144-147
The Breakdown of a Tetrapeptide by Yeast Aminopeptidase I: Kinetic Analysis and Computer Simulation....Pages 148-153
Croton Oil Induced Collagenolitic Activity in the Mouse Skin....Pages 154-162
Proteolytic Degradation of Insulin and Glucagon by Enzymes of Rat Liver....Pages 163-166
Intracellular Protein Catabolism in Muscle....Pages 167-182
Protein Turnover of Rat Skeletal Muscle After Denervation....Pages 183-190
On the Lysosomal Role in Skeletal Muscle Catabolism Following Denervation....Pages 191-198
The Importance of Protein Breakdown in Muscle as a Regulatory Process....Pages 199-204
Protein Degradation in Spontaneously Degenerating Muscles....Pages 205-208
Separation of Some Peptide Hydrolases from Skeletal Muscle....Pages 209-214
Proteinases that Digest the Connective Tissue Matrix....Pages 215-223
Cathepsins from Experimental Granuloma and their action on Collagen....Pages 224-229
Cathepsin D of Rat Thoracic Duct Lymphocytes: Unusual Intracellular Localization and Biochemical Properties....Pages 230-239
Purification and Some Properties of Native and Immobilized Cathepsin D....Pages 240-249
Isolation of Cathepsin D by Affinty Chromatography on Immobilized Pepstatin....Pages 250-254
Synthetic Octapeptide Inhibitor of Cathepsin D....Pages 255-258
Lung Proteases and Protease Inhibitors....Pages 259-269
The Influence of Cathepsin D Inhibitors (Pepstatin and Anticatheptic Antibodies) on Serum Cathepsin and Lysozyme Activity of 60 Co Irradiated Animals....Pages 270-274
The Relationship Between Cathepsin D Activity and Antibacterial Activity in Subcellular Fractions of Rabbit and Chicken Polymorphonuclear Leucocytes....Pages 275-281
On the Specificity of Cathepsin B2....Pages 282-289
A Thiol Dependent Acid Protease....Pages 290-298
Cathepsin L and Cathepsin B3 from Rat Liver Lysosomes....Pages 299-303
Activity of Acid and Neutral Proteinases in Bone Marrow of Busulfan Treated Rats....Pages 304-309
The Neutral Proteinases of Human Spleen....Pages 310-316
Isolation and Some Properties of Horse Leucocyte Neutral Proteases....Pages 317-326
Neutral Proteinases and Inhibitors of Leucocytes....Pages 327-342
Neutral Proteinases of Bovine Liver....Pages 343-348
The Catabolism of two Adrenocorticotrophin Analogues Following Intravenous Injection....Pages 349-350
An Autoradiographic Study of the Renal Uptake and Metabolism of a Synthetic Adrenocorticotrophin....Pages 351-352
Back Matter....Pages 353-368