مشخصات کتاب

Insulin Resistance: Insulin Action and Its Disturbances in Disease

ویرایش:  
 
سری:  
ISBN (شابک) : 9780470850084, 9780470011324 
ناشر:  
سال نشر: 2004 
تعداد صفحات: 603 
زبان: English 
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) 
حجم فایل: 5 مگابایت 

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توضیحاتی در مورد کتاب مقاومت به انسولین: عملکرد انسولین و اختلالات آن در بیماری

توضیحاتی درمورد کتاب به خارجی

Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects.

The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined.
* Provides an expert review of the phenomenon of insulin resistance
* Brings together a host of recent research for the first time
* Written by leading experts in biological and clinical researchContent:
Chapter 1 The Insulin Receptor and Downstream Signalling (pages 1–62): Ken Siddle
Chapter 2 Insulin?Mediated Regulation of Glucose Metabolism (pages 63–85): Daniel Konrad, Assaf Rudich and Amira Klip
Chapter 3 Insulin Action on Lipid Metabolism (pages 87–103): Keith N. Frayn and Fredrik Karpe
Chapter 4 The Effect of Insulin on Protein Metabolism (pages 105–132): Laura J. S. Greenlund and K. Sreekumaran Nair
Chapter 5 Genetically Modified Mouse Models of Insulin Resistance (pages 133–153): Gema Medina?Gomez, Christopher Lelliott and Antonio J. Vidal?Puig
Chapter 6 Insulin Resistance in Glucose Disposal and Production in Man with Specific Reference to Metabolic Syndrome and Type 2 Diabetes (pages 155–178): Henning Beck?Nielsen, Frank Alford and Ole Hother?Nielsen
Chapter 7 Central Regulation of Peripheral Glucose Metabolism (pages 179–206): Stanley M. Hileman and Christian Bjorb?k
Chapter 8 Relationship between Fat Distribution and Insulin Resistance (pages 207–235): Philip G. McTernan, Aresh Anwar and Sudhesh Kumar
Chapter 9 PPAR? and Glucose Homeostasis (pages 237–267): Robert K. Semple and Stephen O'Rahilly
Chapter 10 Adipokines and Insulin Resistance (pages 269–295): Daniel K. Clarke and Vidya Mohamed?Ali
Chapter 11 Dietary Factors and Insulin Resistance (pages 297–316): Jeremy Krebs and Susan Jebb
Chapter 12 Physical Activity and Insulin Resistance (pages 317–400): Nicholas J. Wareham, Soren Brage, Paul W. Franks and Rebecca A. Abbott
Chapter 13 Genetics of the Metabolic Syndrome (pages 401–450): George Argyropoulos, Steven Smith and Claude Bouchard
Chapter 14 Insulin Resistance and Dyslipidaemia (pages 451–466): Benoit Lamarche and Jean?Francois Mauger
Chapter 15 Insulin Resistance, Hypertension and Endothelial Dysfunction (pages 467–483): Stephen J. Cleland and John M. C. Connell
Chapter 16 Insulin Resistance and Polycystic Ovary Syndrome (pages 485–509): Neus Potau
Chapter 17 Syndromes of Severe Insulin Resistance (SSIRs) (pages 511–533): David Savage and Stephen O'Rahilly
Chapter 18 Therapeutic Strategies for Insulin Resistance (pages 535–560): Harpal S. Randeva, Margaret Clarke and Sudhesh Kumar
Chapter 19 Drug Therapy for Insulin Resistance – a Look at the Future (pages 561–585): Bei B. Zhang and David E. Moller

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