Inflammatory Cells and Mediators in CNS Diseases (New Horizons in Therapeutics , Vol 2)

Book Cover......Page 1
Title......Page 4
Contents......Page 5
Preface to the Series......Page 12
Preface to the Volume......Page 14
Contributors......Page 18
Perspectives in Neuroinjury and Disease......Page 24
Unique Aspects of Inflammation in the Central Nervous System......Page 44
Parenchymal Cell Death and Leukocyte;Endothelial Cell Interaction in Acute Experimental Inflammation......Page 62
Apoptosis in Neurodegenerative Diseases: New Therapeutic Opportunities......Page 76
Constitutive Nitric Oxide Synthase and Ischemic/Excitotoxic Brain Injury......Page 108
Osteopontin in Oxidative Stress Responses......Page 120
Inducible Nitric Oxide Synthase Gene Expression and Ischemic Brain Damage......Page 136
Inflammatory Factors Regulating the Blood-Brain Barrier......Page 160
The Role of Superoxide Radicals in the Pathogenesis of Cerebral Ischemic Cell Death......Page 180
Cytokine Expresssion in Brain Tumors: Its Role in Tumor Biology and Tumor-associated Immune Responses......Page 192
The Inflammatory Mediator Platelet-Activating Factor and the Inducible Prostaglandin Synthase (COX-2) Gene in CNS Diseases......Page 268
Cytokines and Matrix Metalloproteinases in Inflammation of the Blood-Brain Barrier......Page 280
Stroke Studies with Anti-Inflammatory Agents......Page 290
Complement in Brain Inflammation and Injury......Page 306
Gene Expression in Stroke......Page 320
Leukocyte Adhesion Molecules in the Treatment of Stroke......Page 334
Tumor Necrosis Factor  in Stroke and Neurotrauma......Page 350
Cytokine Mechanisms in Induced Brain Tolerance to Injury......Page 372
Kinins and CNS Injury and Inflammation: Effect of the Bradykinin B2 Antagonist, CP-0597, in Animal Models of Stroke......Page 384
DNA Damage and Repair: An Alternative Mechanism of Cell Death after Cerebral Ischemia......Page 402
Selectins, ICAMs, and Integrins in CNS Injury......Page 418
Chemokines in Central Nervous System Inflammation......Page 436
The Expression and Function of Cell Adhesion Molecules in Neurodegenerative Disease......Page 460
Cytokines in Acute Brain Injury and Stroke......Page 494
Inflammation-Mediated Neuronal Cell Injury......Page 506
Neurogenomics and the Discovery of Novel Inflammatory Mediators in the Central Nervous System......Page 520
Index......Page 536