Immunology of Milk and the Neonate

Front Matter....Pages i-xiii
Characteristics of Human Milk Antibodies and their Effect in Relation to the Epidemiology of Breastfeeding and Infections in a Developing Country....Pages 1-15
T Cell Development in the Fetus and Neonate....Pages 17-29
Growth Factors and the Development of Neonatal Host Defense....Pages 31-39
Amniotic Fluid: The First Feeding of Mucosal Immune Factors....Pages 41-49
Ontogeny of the Secretory IgA System in Humans....Pages 51-57
IgA-Secreting Cells in the Blood of Premature and Term Infants: Normal Development and Effect of Intrauterine Infections....Pages 59-69
Development of T Cells with Memory Phenotype in Infancy....Pages 71-76
The Effect of Human Milk, Protein-Fortified Human Milk and Formula on Immunologic Factors of Newborn Infants....Pages 77-85
Ontogeny of the Mucosal Immune Response in Children....Pages 87-92
Are Cytokines in Human Milk?....Pages 93-97
The Developing Gastrointestinal Tract and Milk-Borne Epidermal Growth Factor....Pages 99-105
Growth Factor Signal Transduction in Human Intestinal Cells....Pages 107-112
Role of IL-6 in Human Antigen-Specific and Polyclonal IgA Responses....Pages 113-121
Immunological Properties and Differentiation Potential of Human Colostral Lymphocytes of B Cell Lineage....Pages 123-129
The Effects of Colostrum on Neutrophil Function: Decreased Deformability with Increased Cytoskeleton-Associated Actin....Pages 131-136
Peroxidases in Human Milk....Pages 137-144
Lactoferrin Binding to its Intestinal Receptor....Pages 145-150
Free Fatty Acids and Monoglycerides: Anti-Infective Agents Produced during the Digestion of Milk Fat by the Newborn....Pages 151-158
The Role of Milk-Derived Antimicrobial Lipids as Antiviral and Antibacterial Agents....Pages 159-165
Anti-Adhesive Molecules in Human Milk....Pages 167-171
The Effect of Human Milk on the Adherence of Enterohemorrhagic E. Coli to Rabbit Intestinal Cells....Pages 173-177
Identification and Use of Protective Monoclonal IgA Antibodies Against Viral and Bacterial Pathogens....Pages 179-182
Production and Use of Monoclonal IgA Antibodies Complexed with Recombinant Secretory Component for Passive Mucosal Protection....Pages 183-185
Epithelial Transport of IgA Immune Complexes....Pages 187-191
Association of Human Milk SIgA Antibodies with Maternal Intestinal Exposure to Microbial Antigens....Pages 193-199
Serum and Breast Milk Antibodies to Food Antigens in African Mothers and Relation to their Diet....Pages 201-206
Modulation of the Immune Response by Maternal Antibody....Pages 207-213
Maternal Determinants of Neonatal Immune Response: Effect of Anti-Idiotype in the Neonate....Pages 215-222
Immunoglobulin G Subclasses in Human Colostrum and Milk....Pages 223-226
Secretory Defenses Against Giardia Lamblia ....Pages 227-233
Epidemiological Perspective of Breastfeeding and Acute Respiratory Illnesses in Infants....Pages 235-240
Serotypes of Rotavirus that Infect Infants Symptomatically and Asymptomatically....Pages 241-247
Immune Response to Rotavirus Vaccines Among Breast-Fed and Nonbreast-Fed Children....Pages 249-254
Recent Advances in Development of a Rotavirus Vaccine for Prevention of Severe Diarrheal Illness of Infants and Young Children....Pages 255-264
Rotavirus Specific Breast Milk Antibody in Two Populations and Possible Correlates of Protection....Pages 265-269
Human Milk and HIV Infection: Epidemiologic and Laboratory Data....Pages 271-280
Characterization of a Human Milk Factor that Inhibits Binding of HIV GP120 to its CD4 Receptor....Pages 281-291
Breast Milk Transmission of Cytomegalovirus (CMV) Infection....Pages 293-299
Antibody Responses to Cytomegalovirus in Serum and Milk of Newly Delivered Mothers....Pages 301-305
Protection of Neonatal Mice from Fatal Reovirus Infection by Immune Serum and Gut Derived Lymphocytes....Pages 307-315
Passive Immune Protection from Diarrhea Caused by Rotavirus or E. Coli : An Animal Model to Demonstrate and Quantitate Efficacy....Pages 317-327
The Antibody Response in Infants After Colonization of the Intestine with E. coli O83. Artificial Colonization Used as a Prevention Against Nosocomial Infections....Pages 329-335
Antibodies to Streptococci Pneumoniae in Sera and Secretions of Mothers and their Infants....Pages 337-344
The Potential Impact of Group B Streptococcal Antibodies in Breast Milk....Pages 345-351
IgA Proteases of Haemophilus Influenzae Dividing in Human Milk are Inhibited by IgA Antibody in the Milk....Pages 353-359
Bovine Lactogenic Immunity Against Pediatric Enteropathogens....Pages 361-367
Milk Secretory IgA Related to Shigella Virulence Antigens....Pages 369-373
Cortisone Strengthens the Intestinal Mucosal Barrier in a Rodent Necrotizing Enterocolitis Model....Pages 375-380
The Relevance of Immunoglobulin in the Prevention of Necrotizing Enterocolitis....Pages 381-389
Strategies for the Prevention of Food Allergic Associated Atopic Disease....Pages 391-396
Secretory Antibodies to Cow Milk Proteins and to Respiratory Syncytial Virus....Pages 397-403
Characterization of Cow Milk Proteins in Human Milk: Kinetics, Size Distribution, and Possible Relation to Atopy....Pages 405-410
Transfer of Enterally Administered Proteins from Lactating Mouse to Neonate: The Potential Role of Environmental Contamination....Pages 411-415
Levels of IgA and Cow Milk Antibodies in Breast Milk vs. the Development of Atopy in Children. Low Colostral IgA Associated with Cow Milk Allergy....Pages 417-425
Sensitization Via the Breast Milk....Pages 427-436
Management of Infants with Cow Milk Allergy....Pages 437-443
Breast Milk and Special Formulas in Prevention of Milk Allergy....Pages 445-451
Atopy Prophylaxis in High-Risk Infants....Pages 453-458
Natural History and Immunological Markers in Children with Cow Milk Allergy....Pages 459-465
IgG, IgA, and IgE Antibodies to Cow Milk Proteins in an Allergy Prevention Study....Pages 467-473
The Clinical Expression of Allergy in Breast-Fed Infants....Pages 475-480
Back Matter....Pages 481-488