Immunological and Clinical Aspects of Multiple Sclerosis: The Proceedings of the XXV Anniversary Symposium of the Belgian Research Group for Multiple Sclerosis

Front Matter....Pages i-xxvi
Front Matter....Pages 1-1
Auto-immunity....Pages 3-6
Occurrence of an internal image of measles haemagglutinin in an anti-idiotype immune response....Pages 7-9
Studies on the intrathecal humoral immunity in multiple sclerosis....Pages 10-14
Antibody to viral antigens in multiple sclerosis demonstrated by ELISA method....Pages 15-15
Cerebrospinal fluid antibodies detect brain antigens....Pages 16-19
Immune complexes and the complement factors C4 and C3 in cerebrospinal fluid and serum from patients with multiple sclerosis....Pages 20-22
Characterization of circulating immunocomplexes in multiple sclerosis....Pages 23-23
Immunoelectrophoretic characterization of immune complexes from CSF of multiple sclerosis patients....Pages 24-27
Neurosurgery in the rehabilitation of hyperspasmodic and painful paraplegia in multiple sclerosis. Functional results in selective posterior rhizotomy....Pages 28-28
Immunological aspects of multiple sclerosis....Pages 29-38
Myelin basic protein and its antibodies in the cerebrospinal fluid in experimental allergic encephalomyelitis, multiple sclerosis and other diseases....Pages 39-39
Identification of myelin basic protein (MBP) as an antigenic component of circulating immune complexes (CIC) in MS patients....Pages 40-46
Sensitization of cerebrospinal fluid and peripheral blood lymphocytes to brain glycolipids in multiple sclerosis....Pages 47-54
Interferon production and natural killer (NK) activity in multiple sclerosis....Pages 55-58
 α -Albumin in cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases — comparison with other brain specific proteins....Pages 59-62
The Transferrin-Tau ratio of the CSF....Pages 63-69
Auto-antibodies to brain specific proteins....Pages 70-71
The effect of monoclonal anti-T cell antibodies on the clinical course of experimental allergic encephalomyelitis in rats....Pages 72-74
Changes of polymorphonuclear neutral proteinase activity in multiple sclerosis patients before and after plasma exchanges....Pages 75-82
Acid phosphatase activity of cerebrospinal fluid cells in multiple sclerosis and related neurological disorders....Pages 83-87
Front Matter....Pages 1-1
Influence of human allergic encephalitogenic peptide on platelet aggregation in multiple sclerosis....Pages 88-90
The effect of dietary supplementation of enriched marine oil on serum levels of ω -3 and ω -6 polyunsaturated fatty acids in multiple sclerosis....Pages 91-98
Front Matter....Pages 99-99
Immunological treatments in multiple sclerosis....Pages 101-109
Multiple sclerosis incidence material data used in the design of clinical trials....Pages 110-118
Long term treatment with azathioprine in multiple sclerosis patients....Pages 119-124
Long-term immunotherapy in MS....Pages 125-125
Immunosuppression with cyclophosphamide in multiple sclerosis....Pages 126-134
Treatment of progressive multiple sclerosis by the combined application of antilymphocyte serum, azathioprine and prednisone....Pages 135-143
Clinical trials of a synthetic polypeptide (Copolymer I) for the treatment of multiple sclerosis....Pages 144-150
Lympho-plasmapheresis in multiple sclerosis: effect on clinical and immunological parameters....Pages 151-156
Plasmapheresis in multiple sclerosis: cerebrospinal fluid changes after treatment....Pages 157-160
Transfer factor treatment in MS: A 3 year prospective double-blind study (1982–1985)....Pages 161-165
Experiences with immunoglobulin-G infusions in the treatment of acute multiple sclerosis....Pages 166-175
Dietary supplementation with polyunsaturated fatty acids in acute remitting multiple sclerosis....Pages 176-183
Essential fatty acids in the serum and cerebrospinal fluid of multiple sclerosis patients....Pages 184-194
The effect of large dose prednisone therapy on intrathecal IgG production in multiple sclerosis....Pages 195-201
Changes in T-cell subsets according to the course of MS and immunosuppressive treatment....Pages 202-205
T lymphocyte subsets in the CSF in various stages of MS....Pages 206-209
Front Matter....Pages 211-211
Clinical and paraclinical assessment of spinal cord dysfunction....Pages 213-213
Functional testing of the spinal cord....Pages 214-214
Front Matter....Pages 211-211
Increased flexor or reflex and spastic contracture in flexion, mechanisms and management....Pages 215-218
Tizanidine, a new antispastic agent: 6 years clinical experience in 152 MS patients....Pages 219-225
Objective assessment of the myorelaxant properties of tizanidine....Pages 226-226
Is electrical stimulation of the spinal cord useful in MS patients?....Pages 227-233
Front Matter....Pages 235-235
A silica gel radioimmunoassay determination of cerebrospinal fluid myelin basic protein levels of various demyelinating disease syndromes associated with multiple sclerosis....Pages 237-239
T-lymphocyte subpopulations in patients with MS: a study of 84 cases....Pages 240-245
Multiple sclerosis cerebrospinal fluid lymphocytes secretion in vitro : effect on myelinated cultures....Pages 246-249
Isotopic cisternography in multiple sclerosis: possible correlations with disease course....Pages 250-252
Management of acute multiple sclerosis by a long acting intrathecally administered corticosteroid....Pages 253-256
Diagnostic value of α 2 -macroglobulin crossed immunoelectrophoresis in multiple sclerosis....Pages 257-261
The IgG index and the diagnosis of MS: a Bayesian approach....Pages 262-262
Neuro-urological problems in MS: diagnosis and treatment....Pages 263-269
Front Matter....Pages 271-271
Central nervous system involvement in clinically pure optic neuritis (a pilot study in 25 patients)....Pages 273-277
Prognostic value of CSF IgG in monosymptomatic optic neuritis....Pages 278-281
Cerebrospinal fluid findings in isolated optic neuritis compared to multiple sclerosis....Pages 282-291
Ophthalmological manifestations in multiple sclerosis. A statistical review of 1728 cases (1180 confirmed cases)....Pages 292-299
Flight of colours-test in MS and NRB patients....Pages 300-301
The early diagnostic yield of multimodality evoked potentials: a 4.8 year prospective study on 171 patients....Pages 302-308
Effect of heating on VER of multiple sclerosis patients apparently free of optic neuritis....Pages 309-315
Front Matter....Pages 317-317
Multiple sclerosis: a case-control study. A preliminary report....Pages 319-326
Front Matter....Pages 317-317
Numerical classification of multiple sclerosis....Pages 327-332
HLA-determination in twins with multiple sclerosis....Pages 333-336
Multiple sclerosis and myasthenia gravis....Pages 337-341
Intellectual impairment in multiple sclerosis....Pages 342-345
Multiple sclerosis: a conceptual reappraisal....Pages 346-361
A rarely reported multifocal demyelinating disease: pancreatic encephalopathy....Pages 362-362
Plaques, necrotic myelopathy and Rosenthal fibre reaction: glial pathology in MS....Pages 363-363
Comments on MS-compensation in West Germany....Pages 364-366
Multiple sclerosis and CT: a correlative study — preliminary results (43 cases)....Pages 367-367
Multiple sclerosis and CT: a correlative study — preliminary results (39 cases)....Pages 368-372
Multiple sclerosis: some preliminary findings of a neurological and medical-sociological prospective research project....Pages 373-378
Front Matter....Pages 379-379
Measles antibodies, anti-proteinase and plasminogen distribution in serum and plasma from patients affected with multiple sclerosis and patients affected with non-neurological diseases....Pages 381-383
The benign form of multiple sclerosis....Pages 384-386
Optic neuritis: laboratory tests for diagnosis and prognosis for the development of multiple sclerosis....Pages 387-391
Detection of S-100 protein in the cerebrospinal fluid of animals with acute experimental allergic encephalomyelitis....Pages 392-397
Estimation of levels of IgG to multiple sclerosis specific brain antigens in the cerebrospinal fluid of MS patients....Pages 398-398
Increased T-helper cell levels in cerebrospinal fluid....Pages 399-402
Laboratory test for hyperactivity (HA) in children: is childhood HA related to multiple sclerosis?....Pages 403-408
Isoelectric focusing of the CSF gammaglobulins in 2594 patients....Pages 409-409
Modulation of immunity in multiple sclerosis: a double-blind levamisole-placebo controlled study in 85 patients....Pages 410-410
Front Matter....Pages 379-379
Brain antigens detected by cerebrospinal fluid from multiple sclerosis patients....Pages 411-415
Cell-mediated immunity in progressive forms of multiple sclerosis treated by lympho-plasmapheresis....Pages 416-416
Myelin basic protein in cerebrospinal fluid, detected by an enzyme-immunoassay, and its diagnostic value....Pages 417-420
Onset-related values of serotonin, ceruloplasmin and 5-HIAA in patients with MS....Pages 421-421
Visual evoked potentials: a contribution in the assessment of multiple sclerosis....Pages 422-426
Shared antibrain specificities of cerebrospinal fluid and synovial fluid antibodies....Pages 427-431
Eye movement disorders in multiple sclerosis and optic neuritis....Pages 432-432
Do venous refluxes hurt the brain in MS? The fundamental problem....Pages 433-440
Blood-CSF barrier permselectivity and measurement of intrathecal IgG synthesis in multiple sclerosis....Pages 441-447
Azathioprine vs. transfer factor in multiple sclerosis patients: preliminary data....Pages 448-453
Epidemiology of multiple sclerosis in Italy. A further descriptive study in Barbagia, Sardinia....Pages 454-458
Antibrain antibody adsorption on microtitre plates....Pages 459-462
Search for viral nucleic acid sequences in the human central nervous system....Pages 463-469
Ultrastructural study of virus-like particles in an acute case of multiple sclerosis....Pages 470-477
Back Matter....Pages 479-492