Immunodeficient Animals for Cancer Research

Front Matter....Pages i-xii
Immunodeficient animals....Pages 1-4
Inherited immunological defects in laboratory animals....Pages 5-23
The importance of disease in immunodeficient mice and rats....Pages 25-41
Pathological observations on nude mice....Pages 43-54
Morphology of non-lymphatic cells in the lymph node of the nude mouse....Pages 55-65
Some aspects of immunology in the nude rat....Pages 67-79
Comparison of the growth of xenografts in various kinds of immunodeficient mice....Pages 81-94
Heterotransplantation of human malignant tumours to athymic nude mice....Pages 95-103
Tumour transplantation in nude rats and mice....Pages 105-111
Transplantation of canine tumours into immunosuppressed dogs and nude mice....Pages 112-124
Human tumour xenografts in athymic nude mice: non-specific host rejection responses....Pages 125-133
A prospective test for human tumour rejection antigens?....Pages 135-135
Metastasis of human tumours implanted in immunodeficient mice....Pages 137-143
Metastatic behaviour of human colon carcinoma in nude mice....Pages 145-158
Lewis lung tumour growth and metastases in nude mice....Pages 159-165
Tumour metastasis in thymectomised and athymic rats....Pages 167-177
The therapeutic response of human tumour xenografts....Pages 179-189
Cytofluorometric analysis of tumours in nude mice....Pages 191-206
Identification and separation of mouse and human components of heterotransplanted human tumours....Pages 207-220
Viral contaminants of xenografts....Pages 221-225
The potential role of xenografts in the investigation of the clonal structure of human tumours....Pages 227-234
Back Matter....Pages 235-245