Immunobiology of Proteins and Peptides VI: Human Immunodeficiency Virus, Antibody Immunoconjugates, Bacterial Vaccines, and Immunomodulators

Front Matter....Pages i-xiii
Structure and Function in Recombinant HIV-1 gp120 and Speculation about the Disulfide Bonding in the gp120 Homologs of HIV-2 and SIV....Pages 1-14
The Lentivirus Regulatory Proteins REV and REX are Site Specific RNA Binding Proteins....Pages 15-22
HIV-1 Neutralizing Antibody and Approaches to the Envelope Diversity Problem....Pages 23-26
Molecular Mechanisms in the Pathogenesis of AIDS-Associated Kaposi’s Sarcoma....Pages 27-38
Structure-Function Analysis of the HIV Glycoprotein....Pages 39-46
Maternal Antibody Epitope Mapping in Mother-to-Child Transmission of HIV....Pages 47-52
Immunogenicity of Synthetic Peptides Corresponding to Various Epitopes of the Human Immunodeficiency Virus Envelope Protein....Pages 53-62
Common Sequence in HIV-1 GP41 and HLA Class II Beta Chains can Generate Crossreactive Autoantibodies with Immunosuppressive Potential Early in the Course of HIV-1 Infection....Pages 63-69
Isolation and Characterization of the Neutralizable Epitope of Simian Retrovirus-1 (SRV-1) and of the Cell Receptor for the Virus....Pages 71-77
Complexes and Conjugates of cis-Pt for Immunotargeted Chemotherapy....Pages 79-90
Radiolabeled Antibody Therapy of Human B Cell Lymphomas....Pages 91-96
Activation of Prodrugs by Antibody-Enzyme Conjugates....Pages 97-105
Cancer Imaging and Therapy with Radiolabeled Antibodies....Pages 107-117
Genetic Approaches to a Vaccine for Pertussis....Pages 119-127
Strategies for Type-Specific Glycoconjugate Vaccines of Streptococcus pneumoniae ....Pages 129-148
Immunoprophylaxis of Otitis Media....Pages 149-158
Protection against Streptococcal Pharyngeal Colonization with Vaccines Composed of M Protein Conserved Regions....Pages 159-167
Oral Delivery of Antigens in Live Bacterial Vectors....Pages 169-184
Augmentation by Interleukins of the Antibody Response to a Conjugate Vaccine against Haemophilus influenzae B....Pages 185-190
Factors Produced by Stromal Cells Involved in B-Cell Development....Pages 191-197
Suppressor T Cells Induced in Vivo by Tolerogenic Conjugates of a Given Antigen and Monomethoxypolyethylene Glycol Downregulate Antibody Formation Also to a Second Antigen, if the Latter is Presented as a Covalent Adduct with the Former....Pages 199-206
A Purified Saponin Acts as an Adjuvant for a T-Independent Antigen....Pages 207-210
Modified-Live Infectious Bovine Rhinotracheitis Virus (IBRV) Vaccine Expressing Foot-and-Mouth Disease Virus (FMDV) Capsid Protein Epitopes on Surface of Hybrid Virus Particles....Pages 211-220
Development of Non-Toxigenic Vaccine Strains of Bordetella pertussis by Gene Replacement....Pages 221-225
Immunogenicity of Lipopolysaccharide Derived from Brucella abortus: Potential as a Carrier in Development of Vaccines for AIDS....Pages 227-233
Antigenic Mapping of Light Chains and T Cell Receptor β Chains....Pages 235-242
Epitope Mapping Studies of Snake Venom Phospholipase A 2 Using Monoclonal Antibodies....Pages 243-248
Identification of Epitopes of the Receptor Binding Subunit of Cholera Toxin by Synthetic Peptide and CBIB Approaches....Pages 249-254
Autoimmune Recognition Profile of the Alpha Chain of Human Acetylcholine Receptor in Myasthenia Gravis....Pages 255-261
Paucity of Humoral Response in Patients to Glioma-Associated Antigen(s): Antigen Localization by Immunofluorescence....Pages 263-270
Preparation and Characterization of Antisera and of Murine Monoclonal Antibodies to Human Glioma-Associated Antigen(s)....Pages 271-283
A Peptide Antibody that Specifically Inhibits Cathepsin L....Pages 285-288
Immunomodulating Properties of Corticotropin-Releasing Factor....Pages 289-293
Back Matter....Pages 295-298