Hypoxia, Metabolic Acidosis, and the Circulation

Front Matter....Pages i-x
Front Matter....Pages 1-1
Circulatory Regulation during Hypoxia and Hypercapnia....Pages 3-20
Regulation of Myocardial Blood Flow and Oxygen Delivery during Hypoxia....Pages 21-32
Acid—Base Status and Blood Lactate at Extreme Altitude....Pages 33-44
Effects of Ischemia, Hypoxia, and Acidosis on Cardiac Systolic and Diastolic Function, and Glycolytic Metabolism in Normal and Hypertrophied Hearts....Pages 45-81
Front Matter....Pages 83-83
Clinical Implications of the Pathophysiology of Lactic Acidosis: The Role of Defects in Lactate Disposal....Pages 85-98
Acidosis and the Pulmonary Circulation....Pages 99-115
Pathogenesis of Metabolic Acidosis with Hypoxia....Pages 116-138
Effects of Sodium Bicarbonate on Myocardial Metabolism and Circulatory Function during Hypoxia....Pages 139-174
Alkalinizing Agents for the Treatment of Cardiac Arrest....Pages 175-195
Therapy of Lactic Acidosis: Alternatives to Sodium Bicarbonate....Pages 196-210
Back Matter....Pages 211-215