Hypothermia for Acute Brain Damage: Pathomechanism and Practical Aspects

Front Matter....Pages I-XI
Front Matter....Pages 1-1
Historical Review of the Development of Brain Hypothermia....Pages 3-16
Front Matter....Pages 17-17
A Review of the Protective Effects of Hypothermia on the Axonal and Vascular Pathobiology Associated with Traumatic Brain Injury....Pages 19-23
Factors Regulating Hypothermic Protection in Experimental Models of Brain Injury....Pages 24-28
Effects of Brain Hypothermia on Brain Edema Formation After Intracerebral Hemorrhage in Rats....Pages 29-35
Hypothermia Prolongs Survival Time of Severely Septic Rats: A Study Using a Computer-Supported Multichannel Thermoregulatory System....Pages 36-40
Influence of Hypothermia on Neuroprotective Effect of Inhibiting Neurotransmitters and Agonists of Their Receptors....Pages 41-46
Front Matter....Pages 47-47
A New Concept of Brain Hypothermia Treatment and Pitfalls in Intensive Care Unit Hypothermia Management....Pages 49-75
Front Matter....Pages 77-77
Is Hypothermia Beneficial by Preventing Fever?....Pages 79-83
Management of Induced Hypothermia in the Intensive Care Unit....Pages 84-89
Microdialysis for Time Course of Extracellular Glutamate in Poor-Grade Aneurysm Patients: Preliminary Study....Pages 90-93
Mild Brain Hypothermia Suppresses Oxygen Free Radicals in Patients with Neuroemergency: An Ex Vivo Electron Spin Resonance Study....Pages 94-97
Mathematical Analysis of Extremity Immersion Cooling for Brain Temperature Management....Pages 98-101
Rapid Induction of Brain Hypothermia by Selective Intra-Arterial Perfusion of Crystalloid Solution in an Animal Model....Pages 102-105
Combination of Forced Air Cooling, Cooling by Circulating Water Mattress, and Intravenous Bolus Infusion of Iced Saline Is an Effective and Safe Technique for Induction of Mild Hypothermia During Cerebral Aneurysm Surgery....Pages 106-108
Automatic Air-Cooling Incubating System for Brain Hypothermia Treatment....Pages 109-115
Automatic Temperature Management System in Patients with Mild Hypothermia: Three Case Reports....Pages 116-121
Intraoperative Mild Hypothermia in Neurosurgery....Pages 122-128
The Importance of Nursing Management in the Treatment of Brain Hypothermia....Pages 129-132
Front Matter....Pages 133-133
Moderate Hypothermia Attenuates the Endothelium-Dependent Pial Arteriole Dilatation but Not the Endothelium-Independent Response in Rats....Pages 135-140
Pial Microcirculation Evaluated by Closed Cranial Window Method 7 Days After Impact Acceleration Injury in Rats: Does Post-Traumatic Hypothermia Provide Persisting Pial Vascular Protection?....Pages 141-144
Front Matter....Pages 145-145
Hypothermia Following Traumatic Brain Injury in Children....Pages 147-157
Clinical Study of Brain Magnetic Resonance Images in Infants with Brain Hypothermia....Pages 158-163
Study on Body Temperature Monitoring During Brain Hypothermia in Newborn Infants with Severe Hypoxic-lschemic Encephalopathy....Pages 164-167
Neuropsychological Recovery in Pediatric Patients with Acute Subdural Hematoma Treated with Mild Hypothermia Therapy: Report of Two Cases....Pages 168-173
Adjunctive Therapy Application of Hyperbaric Oxygen Therapy in Children Already Treated with Mild Hypothermia for Disturbance of Consciousness....Pages 174-177
Front Matter....Pages 179-179
The Management of Cerebral Stroke by Brain Hypothermia Treatment....Pages 181-185
The Nordic Cooling Stroke Study—NOCSS. A Multicenter Study of Induced Mild Hypothermia in Acute Stroke Patients. Ongoing Clinical Trial....Pages 186-189
Hypothermia in the Therapy of Ischemic Stroke....Pages 190-194
Correlation of Hypothermia with Decrease of Glutathione Concentration and Tolerance to Cerebral Ischemia....Pages 195-199
Hypothermia Prolongs the Viability of Ischemic Brain Tissue Due to Neuroprotection Linked to Redistribution of Oxygen in Brain: Positron Emission Tomography Study of the Critical First 6h After Stroke in Pigs....Pages 200-203
Neuroprotective Effects of Selective Brain Hypothermia (SBH) on Permanent Focal Cerebral Ischemia in Rats....Pages 204-207
The Effects of Mild and Deep Hypothermia on the Neuronal Activity and Energy Metabolism in Brain Slices In Vitro....Pages 208-214
Ultra-Early Induction of Brain Hypothermia for Patients with Poor-Grade Subarachnoid Hemorrhage....Pages 215-219
Brain Temperature in Patients with Chronic Hydrocephalus After Subarachnoid Hemorrhage....Pages 220-224
The Influence of Mild Hypothermia on the Incidence of Vasospasms in Patients After Severe Subarachnoid Hemorrhage....Pages 225-228
Evaluation of Results of Transcranial Doppler Ultrasonography in Postoperative Brain Hypothermia Therapy for Severe Cases of Subarachnoid Hemorrhage....Pages 229-233
Body Temperature in Stroke: Secondary Stress Phenomenon or Causal Relationship?....Pages 234-237
Important Regional Differences in Brain Tissue Susceptibility to Secondary Damage After Traumatic Brain Injury....Pages 238-245
A Randomized Controlled Trial of Therapeutic Hypothermia in Severe Head-Injured Patients in Japan: Overview of the Protocol....Pages 246-250
The Use of Mild Hypothermia in the Prevention of Secondary Brain Injury....Pages 251-254
Front Matter....Pages 179-179
Hypothermia May Attenuate Not Only Interleukin-6 but also Matrix Metalloproteinase-9 of Systemic and Internal Jugular Blood from the Inflammatory Response to Traumatic Brain Injury in Humans....Pages 255-258
Immune-Enhancing Effect of Arginine on Patients with Severe Traumatic Brain Injuries Who Have Undergone Therapeutic Brain Hypothermia....Pages 259-262
Management of Patients with Traumatic Brain Injury: Hypothermia Therapy and the Importance of Temperature Management....Pages 263-266
Evaluation of Cerebral and Systemic Flow/Metabolism During Brain Hypothermia Therapy....Pages 267-270
Novel Potentials for Emergency Hypothermia: Suspended Animation with Delayed Resuscitation from Exsanguination Cardiac Arrest....Pages 271-277
Resuscitative Hypothermia in Comatose Survivors After Prolonged Cardiopulmonary Resuscitation and B-type Natriuretic Peptide for the Advanced Challenge....Pages 278-286
Survival After Subarachnoid Hemorrhage Using Brain Hypothermia After Recovery of Spontaneous Circulation from Cardiopulmonary Arrest: A Case Report....Pages 287-296
Indication of Brain Hypothermic Therapy in Cardiac Arrest....Pages 297-301
Brain Hypothermic Therapy Following Cardiopulmonary Bypass for Cardiac Arrest Patients Who Did Not Respond to Advanced Cardiovascular Life Support....Pages 302-307
Advanced Challenge in Resuscitative Hypothermia in Patients with Cardiac Arrest on Arrival at the Emergency Room....Pages 308-314
Influence of Brain Hypothermia on Blood lnterleukin-6 Levels on Postresuscitated Patients After Cardiac Arrest....Pages 315-319
Changes of Blood Glutamate Levels in Hypoxic Ischemic Encephalopathy Patients Undergoing Brain Hypothermia....Pages 320-324
Front Matter....Pages 325-325
Persistent Vegetation Means Unconsciousness? How to Manage Vegetation and Memory Disturbances Following Severe Brain Damage....Pages 327-342
Significance of Musico-Kinetic Therapy for Patients with Traumatic Brain Injury Following Therapeutic Hypothermia....Pages 343-346
Back Matter....Pages 347-353