Humoral Immunity in Neurological Diseases

Front Matter....Pages i-xv
Introduction....Pages 1-2
Cellular Immunology in Multiple Sclerosis Introduction and History....Pages 3-16
Cellular Immunology in Multiple Sclerosis Response to Several Viruses....Pages 17-36
Cellular Immunology in Multiple Sclerosis Studies on Immune Regulatory Cells....Pages 37-45
Humoral Immunity in Disease with Special Reference to Multiple Sclerosis....Pages 47-56
Cellular Immune Function to Measles Antigen in Normal Subjects and Multiple Sclerosis: Skin Testing with Autologous CSF and Other Antigens in Multiple Sclerosis....Pages 57-64
Cases of Acute Measles Infection in Multiple Sclerosis Patients....Pages 65-66
Pathogenetic Considerations in Multiple Sclerosis: Is MS a Chronic Variant of Postinfectious Encephalomyelitis ?....Pages 67-74
Heterogeneous Humoral Autoimmune Response in Multiple Sclerosis....Pages 75-81
Subacute Sclerosing Panencephalitis....Pages 83-87
Comparative Neuropathology of Subacute Sclerosing Panencephalitis....Pages 89-95
Cross-Idiotypic Specificity Among Immunoglobulins in Subacute Sclerosing Panencephalitis and Multiple Sclerosis....Pages 97-103
The Virological State in Subacute Sclerosing Panencephalitis....Pages 105-113
Cellular Immunity in Subacute Sclerosing Panencephalitis....Pages 115-120
Progressive Rubella Panencephalitis....Pages 121-126
Multiple Sclerosis and the HLA Determinants....Pages 127-130
HLA and Multiple Sclerosis Genetic Considerations....Pages 131-145
Familial Aspects of Multiple Sclerosis: A Rational Prophylactic Therapy....Pages 147-157
Distribution of Scrapie Infectivity in Various Mouse Tissues At Early Times After Infection....Pages 159-159
Immunoglobulin G Levels in the Sera of Herdwick Sheep With Natural Scrapie....Pages 161-161
Visna in Sheep....Pages 163-182
Old Dog Encephalitis A Clinical and Serological Study....Pages 183-191
Experimental Murine Autoimmune Encephalomyelitis....Pages 193-199
Isoelectric Focusing and Crossed Immunoelectro-Focusing of CSF Proteins — Especially Immunoglobulins....Pages 201-210
Study of Oligoclonal C.S.F. by New Immunofixation Techniques following Electrophoresis on Cellulose Acetate Gel....Pages 211-214
Radioimmunoassay of Immunoglobulins in Cerebrospinal Fluid....Pages 215-220
Measurement of Blood/CSF Permeability Coefficients and of Intrathecal Synthesis of IgG by Capillary Isotachophoresis....Pages 221-227
Study of the Immunoglobulins (IgG, IgA And IgM) in the Cerebrospinal Fluid and Serum in Cases of Suppurative Meningitis and Viral Encephalitis....Pages 229-231
Viral Antibody and Protein Studies of Cerebrospinal Fluid: Diagnostic Usefulness in Multiple Sclerosis....Pages 233-237
The Clinical Significance of Immunoglobulin G (IgG) Determinations in the CSF of Multiple Sclerosis Patients....Pages 239-240
Determination of IgM in the Cerebrospinal Fluid by Particle Counting Immunoassay (PACIA)....Pages 241-245
Local and General Immunity in CNS Diseases....Pages 247-253
Nucleic and Viral Antibodies in Serum and CSF of MS Patients....Pages 255-264
Problems with Qualitative CSF Antibody Tests....Pages 265-270
Immunocytological CSF Alterations and Brain Tumors....Pages 271-275
Study of Humoral Immunity in Cerebrospinal Fluid of Patients Infected with Schistosomiasis....Pages 277-279
Restricted Heterogeneity of the IgG in Neurology....Pages 281-288
Oligoclonal Immune Responses in the Central Nervous System (CNS) in Connection with Virus Infections and CNS Diseases of Unknown Etiology....Pages 289-297
Oligoclonal Virus Antibodies in Healthy Adults and Neurological Patients....Pages 299-301
Immunoglobulin Structure and Function: Idiotypy and the Oligoclonal Response....Pages 303-318
Structural Studies of Immunoglobulins From Patients Affected by Subacute Sclerosing Panencephalitis....Pages 319-325
Insights Gained From the Study of Homogeneous Rabbit Antibodies....Pages 327-359
Circulating Immune Complexes in Neurological Disorders....Pages 361-372
Partial Purification of Multiple Sclerosis Specific Antigens....Pages 373-381
Characterization of Measles Specific Proteins Synthesized from Acutely and Persistently Infected Cells....Pages 383-392
New Polypeptides in Measles Virus Infected Vero Cells....Pages 393-399
The Fate of Antigen-Antibody Complexes on Measles Virus-Induced Giant Cells....Pages 401-404
Induction of Infectious Virus and Viral Surface Antigen in Vero Cells Persistently Infected With Junin Virus....Pages 405-415
Antibody to Oligodendroglia....Pages 417-419
Brain Specific Proteins in Cerebrospinal Fluid....Pages 421-424
Loss of a Brain-Specific Antigen (Alpha 2 -Glycoprotein) in Human Glial Tumors....Pages 425-435
Neuroblastoma Cytoskeleton Shown by Immunofluorescence....Pages 437-440
In Vitro Assessment of the Cell-Mediated Immune Response Towards Human Gliomas....Pages 441-445
Macrophage-Specific Antigens....Pages 447-456
Oligoclonal IgG Bands and Measles Antibodies in Multiple Sclerosis (MS) CSF and Brain Extracts....Pages 457-462
Characterization of the Humoral Immune Response within the CNS by Immunofixation....Pages 463-466
Effects of Serum Factors upon Myelin Organization in Organotypic Cultures of Nervous Tissue....Pages 467-473
The Enhancing Effect of Multiple Sclerosis Brain Homogenates on the Active E Rosette Forming Lymphocytes....Pages 475-479
Further Studies on the Elution of Immunoglobulin from Multiple Sclerosis Brain....Pages 481-492
Interactions of Vaccinia Virus with the Myelin Membrane....Pages 493-497
Functional Impairment of Neuronal Model Cells Induced by Persistent Viral Infection....Pages 499-505
Active T Cells in Blood and CSF in MS and Controls....Pages 507-510
Isolation and Characterization of the T Cell Receptor for the Basic Encephalitogenic Protein in EAE....Pages 511-515
The Influence of the T Immune System on the Appearance of Homogeneous Immunoglobulins in Man and Experimental Animals....Pages 517-522
Regulatory Interactions Between Cells in Immune Responses....Pages 523-540
Inhibiting Factor: General Review....Pages 541-551
B Lymphocyte Function in SSPE: Is There Lack of Suppressor Cells ?....Pages 553-559
Pathogenesis of the MS Lesion: Implications for Therapy....Pages 561-566
Immunologic Factors in the Suppression of Experimental Allergic Encephalomyelitis: Relevence to Multiple Sclerosis....Pages 567-600
Four Laboratory Methods for the Diagnosis of Multiple Sclerosis (MS): A Programme for Treatment and Possible Prophylaxis....Pages 601-607
Suppression of Experimental Allergic Encephalomyelitis With A Synthetic Copolymer — Relevance to Multiple Sclerosis....Pages 609-613
Intrathecal Methotrexate in Multiple Sclerosis....Pages 615-618
Remissions and Exacerbations During Cyclophosphamide and Steroid Therapy in a Case of Neuromyelitis Optica....Pages 619-623
Intrathecal Administration of Interferon in MS Patients ?....Pages 625-627
Renal and Skin Biopsy Findings in Amyotrophic Lateral Sclerosis....Pages 629-641
Some Muscular Changes in Patients With Schistosomiasis....Pages 643-644
Immunological Deficiency in the Down Syndrome: Importance of the Age Factor....Pages 645-652
Conclusions....Pages 653-655
Back Matter....Pages 657-668