Human Physiology: An Integrated Approach,

Front Cover
 Contents in Brief
 Title Page
 Copyright Page
 About the Author
 Dedication
 Acknowledgments
 Contents
 UNIT 1 Basic Cell Processes: Integration and Coordination
 Chapter 1: Introduction to Physiology
 Physiology Is an Integrative Science
 RUNNING PROBLEM What to Believe?
 Emerging Concepts The Changing World of Omics
 Function and Mechanism
 Themes in Physiology
 Focus on ... Mapping
 Theme 1: Structure and Function Are Closely Related
 Theme 2: Living Organisms Need Energy
 Theme 3: Information Flow Coordinates Body Functions
 Theme 4: Homeostasis Maintains Internal Stability. HomeostasisWhat Is the Body\'s Internal Environment?
 Homeostasis Depends on Mass Balance
 Excretion Clears Substances from the Body
 Homeostasis Does Not Mean Equilibrium
 Control Systems and Homeostasis
 Local Control Is Restricted to a Tissue
 Reflex Control Uses Long-Distance Signaling
 Response Loops Begin with a Stimulus
 Feedback Loops Modulate the Response Loop
 Negative Feedback Loops Are Homeostatic
 Positive Feedback Loops Are Not Homeostatic
 Feedforward Control Allows the Body to Anticipate Change
 Biological Rhythms Result from Changes in a Setpoint
 The Science of Physiology. Good Scientific Experiments Must Be Carefully DesignedFocus on ... Graphing
 The Results of Human Experiments Can Be Difficult to Interpret
 CHAPTER SUMMARY
 REVIEW QUESTIONS
 Chapter 2: Molecular Interactions
 RUNNING PROBLEM Chromium Supplements
 Molecules and Bonds
 Most Biomolecules Contain Carbon, Hydrogen, and Oxygen
 Electrons Have Four Important Biological Roles
 Covalent Bonds between Atoms Create Molecules
 Noncovalent Bonds Facilitate Reversible Interactions
 Noncovalent Interactions
 Hydrophilic Interactions Create Biological Solutions. Molecular Shape Is Related to Molecular FunctionHydrogen Ions in Solution Can Alter Molecular Shape
 Protein Interactions
 Proteins Are Selective about the Molecules They Bind
 Protein-Binding Reactions Are Reversible
 Binding Reactions Obey the Law of Mass Action
 The Dissociation Constant Indicates Affinity
 Multiple Factors Alter Protein Binding
 The Body Regulates the Amount of Protein in Cells
 Reaction Rate Can Reach a Maximum
 CHAPTER SUMMARY
 REVIEW QUESTIONS
 Chapter 3: Compartmentation: Cells and Tissues
 RUNNING PROBLEM Pap Tests Save Lives
 Functional Compartments of the Body. The Lumens of Some Organs Are Outside the BodyFunctionally, the Body Has Three Fluid Compartments
 Biological Membranes
 The Cell Membrane Separates Cell from Environment
 Membranes Are Mostly Lipid and Protein
 Membrane Lipids Create a Hydrophobic Barrier
 Membrane Proteins May Be Loosely or Tightly Bound to the Membrane
 Membrane Carbohydrates Attach to Both Lipids and Proteins
 Intracellular Compartments
 Cells Are Divided into Compartments
 The Cytoplasm Includes Cytosol, Inclusions, Fibers, and Organelles
 Inclusions Are in Direct Contact with the Cytosol.