Host Defenses to Intracellular Pathogens

Front Matter....Pages i-xv
Introduction and Historical Perspective....Pages 1-4
Oxygen Independent Microbicidal Mechanisms of Human Polymorphonuclear Leukocytes....Pages 5-17
Oxidative Metabolism of Leukocytes and Its Relationship to Bactericidal Activity....Pages 19-30
Some Paradoxes of Macrophage Function....Pages 31-50
Genetic Disorders of Granulocyte Function: What they Tell Us about Normal Mechanisms....Pages 51-59
Modulation of Effector Lymphokines....Pages 61-68
Stimulation of Host Resistance to Metastatic Tumors by Macrophage Activating Agents Encapsulated in Liposomes....Pages 69-75
Effect of Prostaglandins on the Production of Interleukin-2....Pages 77-82
Interaction of Mycobacteria with Normal and Immunologically Activated Alveolar Macrophages....Pages 83-98
Guinea Pig Alveolar Macrophages Probably Kill M. Tuberculosis H37Rv and H37Ra In Vivo by Producing Hydrogen Peroxide....Pages 99-104
Interferon and Host Defense Systems....Pages 105-119
Mediator Interactions Regulating Macrophage Secretion of Interleukin 1 and Interferon....Pages 121-126
Macrophage Oxygen-Dependent Killing of Intracellular Parasites: Toxoplasma and Leishmania....Pages 127-143
Immunologic Lesions During Toxoplasma Gondii Infection....Pages 145-150
Immunodepression in BALB/c Mice Infected with Leishmania Tropica ....Pages 151-155
Cellular Mechanisms of Anti-Mycobacterial Immunity....Pages 157-182
Host Response to Infection with Mycobacterium Bovis (BCG) in Mice: Genetic Study of Natural Resistance....Pages 183-188
Cell Mediated Lysis of Lymphocytes Expressing Bacterial Antigens....Pages 189-195
Improvement of Abnormal Lymphocyte Responses in “Atypical” Mycobacteriosis with Indomethacin....Pages 197-201
Immunoregulatory Defects in Leprosy....Pages 203-215
Cellular Mechanisms of Resistance to Listeria Monocytogenes....Pages 217-225
Effect of Interferon Inducers and Purified Mouse Interferon on the Susceptibility of Mice to Infection with Listeria Monocytogenes ....Pages 227-233
Natural Resistance to Listeria Monocytogenes as a Function of Macrophage Inflammatory Response....Pages 235-244
Effect of Acute Nutritional Deprivation on Host Defenses Against Listeria Monocytogenes — Macrophage Function....Pages 245-250
Pilus-Mediated Clearance of Salmonella Typhimurium by the Perfused Mouse Liver....Pages 251-259
Immunity to Salmonella Infection....Pages 261-296
Strain Dependent Variation of Delayed-Type Hypersensitivity in Salmonella Typhimurium Infected Mice....Pages 297-302
Monoclonal Antibodies to Salmonella Typhimurium and Escherichia Coli Lipopolysaccharides....Pages 303-311
Characterization of Monoclonal Antibodies Which Recognize Specific Cell Surface Determinants on Salmonella Typhimurium ....Pages 313-317
Monoclonal Antibodies as Probes for Antigens of Mycoplasma Pulmonis ....Pages 319-326
Electron Microscopic Examination of the Inflammatory Response of Guinea Pig Neutrophils and Macrophages to Legionella Pneumophila ....Pages 327-333
Activation of Macrophages for Killing of Rickettsiae: Analysis of Macrophage Effector Function after Rickettsial Inoculation of Inbred Mouse Strains....Pages 335-353
Parameters of Cellular Immunity in Acute and Chronic Rickettsia Tsutsugamushi Infections of Inbred Mice....Pages 355-360
Lymphokine Stimulated Macrophages Inhibit Intracellular Chlamydia Psittaci Replication by Mechanisms Distinct from Intracellular Inhibition of Toxoplasma Gondii Replication....Pages 361-364
Natural and Acquired Resistance to Trypanosoma Cruzi ....Pages 365-382
Immunity to Fungal Infections....Pages 383-408
Antibody-Independent Mechanisms in the Development of Acquired Immunity to Malaria....Pages 409-423
Intracellular Destruction of Leishmania Tropica by Macrophages Activated in Vivo with Mycobacterium Bovis Strain BCG....Pages 425-431
 In Vitro Macrophage Antimicrobial Activities and In Vivo Susceptibility to Leishmania Tropica Infection....Pages 433-439
Virus-Immune T Cells and Monoclonal Antibodies in the Mouse Influenza Model....Pages 441-447
Escape from Immune Surveillance during Persistent Virus Infection....Pages 449-461
Influence of Viruses on Cells of the Immune Response System....Pages 463-474
Genetically Controlled Resistance to Viruses....Pages 475-487
Macrophage Oxidative Metabolism: A Defense Mechanism Against Virus Infection?....Pages 489-495
Interferon-Induced Augmentation of Natural Killer Cell Activity by Splenocytes from Leukemia Virus Immunosuppressed Mice....Pages 497-501
Immunological Comparison of Ocular Disease Induced by two Strains of Herpes Virus of Different Virulence....Pages 503-508
Cellular Processing of the Large Glycoprotein of Lacrosse Virus (Family Bunyaviridae); Implications for Virion Assembly and Host Defense....Pages 509-515
CMV and Renal Allograft Survival....Pages 517-519
Back Matter....Pages 521-538