Hormone Replacement Therapy and The Brain (Controversial Issues in Climacteric Medicine Series)

Book Cover......Page 1
Half-Title......Page 2
Title......Page 4
Copyright......Page 6
Contents......Page 7
List of Principal Contributors......Page 11
1 Glia and Extracellular Space in the Aging Brain......Page 18
2 Estrogen Regulation of Mitochondrial Function and Impact of the Aging Process......Page 31
3 The Immune System, Estrogen and Brain Aging......Page 49
4 Brain Phenotype of the Aromatase Knock-Out Mouse......Page 59
5 Neurosteroids and γ-aminobutyric Acid Type A Receptor Function and Plasticity......Page 65
6 Sex Hormone Receptors in the Human Hypothalamus in Different Stages of Human Life......Page 74
7 Progesterone in the Nervous System: An Old Player in New Roles......Page 91
8 Testosterone Metabolism and Its Effects on Glial Cells of the Central Nervous System......Page 113
9 Physiological Mechanisms of Menopausal Hot Flushes......Page 123
10 Menopause, Hormone Replacement Therapy and Sleep Disturbance......Page 131
11 Sex Hormones and Headache......Page 142
12 Gender Differences in Affective Disorder: A Brief Review......Page 153
13 Androgen-Insufficiency Syndrome and Women's Sexuality......Page 163
14 Estrogen Replacement Therapy and Mood: The Brain as a Target Tissue of Sex Steroids......Page 174
15 Progestogens and Menopause: Effect on Mood and Quality of Life......Page 181
16 ∆5 -Androgen Replacement Therapy: A New Piece of the Mosaic......Page 197
17 The Perimenopause and Depressive Illness......Page 212
18 Depression in Menopausal Women......Page 225
19 Gender Differences in Anxiety Disorders: The Role of Female Hormones......Page 241
20 Schizophrenia, Menopause and Estrogen Replacement Therapy: A Review......Page 252
21 Unsolved and Controversial Issues Regarding Neuroprotection by Estrogen......Page 266
22 Sex Hormone Receptor Polymorphisms and Cognitive Impairement in Older Men and Women......Page 273
23 Menopause: Risk Factor for Memory Loss or Alzheimer's Disease?......Page 281
24 Depression, Aging and the Metabolic Syndrome......Page 291
25 Hormone Replacement Therapy and Risk of Parkinson's Disease......Page 304
26 Hormone Replacement Therapy and Alzheimer's Disease......Page 311
27 Menopause: It's All in the Brain......Page 319
28 Women, Hormones and Depression......Page 328
29 Methodological Pitfalls in the Study of Estrogen Effects on Cognition and Brain Function......Page 344
30 Safety and Tolerability of Transdermal Testosterone Therapy Versus Placebo in Surgically Menopausal Women Receiving Oral or Transdermal Estrogen......Page 356
31 Selective Estrogen Receptor Modulators: Effects in the Brain......Page 358
Index......Page 376