Histophysiology of the Immune System: The Life History, Organization, and Interactions of Its Cell Populations

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
The Leukocyte-Common Antigen (L-CA) Family....Pages 3-7
The Poly-Ig Receptor — Functional Aspects of Secretory Component Expression....Pages 9-20
Lymphocyte Migration Molecules....Pages 21-29
The Binding of Antigen Presenting Cells to T Lymphocytes....Pages 31-41
Front Matter....Pages 43-43
In Vivo Localization of B Lymphoctye Progenitor Cells in Mouse Bone Marrow....Pages 45-51
Pattern of Distribution of Early B Lineage Cells in Rat Bone Marrow....Pages 53-56
B Cell Precursor Populations in Fetal and Neonatal Rat Liver: Frequency, Topography and Antigenic Phenotype....Pages 57-62
Rat Immunoglobulin Genes have Comparable Patterns of J H Rearrangement in Normal Peripheral B Cells and In Pre-B And Cultured TdT + Cells from Bone Marrow....Pages 63-68
Chicken B Lymphocyte Differentiation: Bursal Microenvironment and Differences in Ontogeny between Normal and SPF Birds....Pages 69-74
Response of the Chicken Bursal Stroma to Treatment with Cyclophosphamide and IBD Virus....Pages 75-80
Age-Dependence of Lymphocyte Production in Peyer’s Patch Follicles in Contrast to the Other Peyer’s Patch Compartments and the Thymus....Pages 81-85
Migration of Newly-Produced Virgin B Cells from Bone Marrow to Secondary Lymphoid Organs....Pages 87-92
Memory B Cells Generated in T Cell-Dependent Antibody Responses Colonise the Splenic Marginal Zone....Pages 93-98
Marginal Zone B Cells and the Localisation of Antigen on Follicular Dendritic Cells....Pages 99-104
CBA/N Mice have Marginal Zone B Cells with Normal Surface Immunoglobulin Phenotype....Pages 105-111
Thymus-Independent Type 2 Responses in Lymph Nodes....Pages 113-117
Both LY-1 B Cells And Conventional B Cells Make Autoantibodies to Bromelain-Treated Autologous Erythrocytes....Pages 119-123
IgG Subclass Distribution in Juvenile Human Tonsil: IgG3 and IgG4 Results of Specific Antibody Production Using Synthetic Peptides....Pages 125-132
Interrelationships of Cell-Substrate and Cell-Cell Adhesion Structures in B-Chronic Lymphocytic Leukemia (B-CLL) Cells....Pages 133-137
Heterogeneity in the Expression of B-Cell Antigen in Non-Hodgkin’s Lymphoma....Pages 139-144
Front Matter....Pages 43-43
Growth Requirements of SJL Lymphomas in Vitro : Effect of BCGF II....Pages 145-153
Morphologicl Diversity of DRC-1 Pospitive Cells: Human Follicular Dendritic Cells and their Relatives....Pages 157-163
Identification of Alkaline Phosphatase Positive Cells in Human Germinal Centres as Follicular Dendritic Cells....Pages 165-169
Isolation of Follicular Dendritic Cells from Human Tonsils and Adenoids. in Vitro Culture....Pages 171-175
Immunohistochemical Study on Cultured FDC-C Enriched Lymphoid Cell Populations....Pages 177-180
Interactions Between Follicular Dendritic Cells and Lymphoid Cells....Pages 181-184
Deposits of Terminal Complement Complex and S-Protein on Follicular Dendritic Cells in Human Lymphoid Tissue....Pages 185-189
Transport of Immune Complexes from the Subcapsular Sinus into the Lymph Node Follicles of the Rat....Pages 191-196
FDC-Iccosome Mediated Antigen Delivery to Germinal Center B Cells, Antigen Processing and Presentation to T Cells....Pages 197-202
Is the Survival of Memory B Cells Dependent on the Persistence of Antigen?....Pages 203-207
Memory B Cells but not Virgin B Cells are Activated in Germinal Centers....Pages 209-214
A Subpopulation of Germinal Center B Cells Differentiate Directly into Antibody Forming Cells upon Secondary Immunization....Pages 215-220
Specific Antibody Forming Cells in Lymphoid Follicles of Spleen: An Aspect of the Late Immune Response....Pages 221-225
Enrichment of Germinal Centre Cells....Pages 227-232
The Germinal Center Precursor Cell is Surface μ and σ Positive....Pages 233-237
Surface IgD Phenotype of Rat Germinal Centre Precursor Cells....Pages 239-243
The De Novo Generation of Germinal Centers is an Oligoclonal Process....Pages 245-250
Changes in the Germinal Centre and Lymphocytic Corona after Peritoneal Inflammation....Pages 251-251
The Cholinergic and Adrenergic Innervation of the Rat Thymus....Pages 255-261
Complex Heterogeneity of the Thymic Stroma....Pages 263-268
Front Matter....Pages 43-43
Thymic Stromal Elements Defined by M.Abs: Ontogeny, and Modulation in Vivo By Immunosuppression....Pages 269-275
Kinetics of Rat Thymic Dendritic Cells in Bone Marrow-Reconstituted Radiation Chimeras....Pages 277-283
Allogeneic Cultured Thymic Fragments in Congenitally Athymic (NUDE) Rats....Pages 285-292
Studies on Thymic Involution: Growth Potential and DNA Repair of the Stromal Cells....Pages 293-298
Production of Interleukin 1 (IL1) by Human Thymic Epithelial Cells (TEC)....Pages 299-305
A Low Density Fraction of Bone Marrow Cells Enriched in Prothymocyte Activity....Pages 307-313
Kinetics of Thymocyte Regeneration in Adult Adriamycin Treated Rats: Evidence for a Bone Marrow Derived Prothymocyte Precursor....Pages 315-321
A Study of Early Events During T Cell Differentiation in Thymic Grafted Nude Mice....Pages 323-331
Vascular Thymustransplantation in Rats: A New Method to Study Thymocyte Kinetics....Pages 333-338
M Receptor and Differentiation of T Lymphocytes in the Developing Human Thymus....Pages 339-344
Homing Receptor Expression in Grafts of Purified Thymic Epithelium....Pages 345-349
In Vitro Binding of L3T4 − Lyt-2 − Pgp-1 + Thymocytes to Thymic Accessory Cells....Pages 351-356
Interactions between Lymphoid Cells and a Thymic Stromal Cell Line in Vitro ....Pages 357-362
Structural and Cellular Changes in the Mouse Thymus During Pregnancy....Pages 363-368
Analysis of Lymphocyte Phenotype in Human Thymomas....Pages 369-374
Thymic Hyperplasia in Myasthenia Gravis: Immuno-Histological Abnormalities and Responsiveness to Recombinant IL2....Pages 375-381
Thymus Homing and Recostitution in Split Dose Irradiated Preleukemic Mice....Pages 383-386
Synovial T Cells Detect Polymorphism of Class II HLA Antigens....Pages 387-392
Activated Inflammatory T Lymphocytes in Rheumatoid Synovitis — Effect of Cyclosporine A and Anti-Tac....Pages 393-395
Inhibition of Splenic T Lymphocytes and Accessory Cell Interaction by Anti-Mac-1 (Monoclonal Antibody to Complement Receptor Type 3)....Pages 397-400
Front Matter....Pages 43-43
Mycobacterium Tuberculosis Antigen Specific Human T-Cell Lines are Cytolytic to Autologous Antigen Pulsed Macrophages....Pages 401-406
Correlation of IL2 Production and Lymphoid Tissue Make-Up in Two Inbred Strains of Rats....Pages 407-411
p145-MR6: A Novel T Cell Surface Molecule with a Role in Tolerance to Self....Pages 413-417
Suppression of Immunoglobulin Production by Germinal Centre HNK-1+ CD3+ Cells....Pages 421-425
Mast Cell Response To Tumor Graft....Pages 427-432
Interleukin-2 Induced Changes in Mononuclear Cell Surface Charge....Pages 433-438
The Target Cells for Rat NK Cells among Allogeneic Bone Marrow Cells....Pages 439-445
Are Lymphokine Activated Killer Cells a Possible Form of Leukaemia Immunotherapy?....Pages 447-450
Blood Leukocyte Natural Killer Activity as an Early Diagnostic Indicator of Leukaemic Relapse....Pages 451-455
Proliferation of Large Granular Lymphocytes in the Rat....Pages 457-461
Establishment of Lymph Node Derived Endothelial Cell Lines Which Show Lymphoid Cell Binding....Pages 465-470
The Expression of Lymphocyte Adhesion Molecules on Cultured High Endothelial Cells....Pages 471-476
Expression and Regulation of an Antigen Specific for Endothelium Involved in Human Lymphocyte Homing....Pages 477-484
Changes in Lymphocyte Binding and Expression of his 22 of High Endothelial Venules in Rat Lymph Nodes after Occlusion of Afferent Lymph Flow....Pages 485-490
Regulation of Functional and Morphological Aspects of High Endothelium in Mouse....Pages 491-497
Substance P-Mediated Modulation of the Primary Antibody Response....Pages 499-503
MEL-14 and LFA-1, Organ Specific and Non-Specific Adhesion Molecules Involved in Homing of Human Lymphocytes....Pages 505-509
Homing Receptor Expression and Migration of Activated Lymphocytes....Pages 511-518
Reversibility of Loss of Homing Receptor Expression Following Activation....Pages 519-524
Endocytic Stripping of Ligands from Migrant Lymphocytes in High Endothelial Venules (HEV): Implications for Immunomodulation vs Viral Pathogenesis....Pages 525-531
Front Matter....Pages 43-43
Xenogeneic Lymphocyte Migration in the Foetal Lamb and Unsuckled Neonatal Piglet: Evidence for the Evolutionary Conservation and Heterogeneity of Migration Determinants....Pages 533-539
Hev Development and Trypsin-Inhibitable Localization of Lymphocytes in the Reaction to Intradermal Pha: a Receptor-Dependent Immigration and Possible Model for Peripheral CMI Reactions?....Pages 541-546
The Migration of Lymphocyte Subsets from Blood to Lymph in the Normal Rat....Pages 547-551
The Physiological Role of the Lung in Lymphocyte Migration....Pages 553-558
Lymphocyte Emigration from the Ovine Thymus: Characterization of Lymphatic Emigrants and Venous Emigrants....Pages 559-563
T Lymphocyte Precursors Migrate Towards Chemotactic Peptides Secreted by Embryonic or Juvenile Thymus....Pages 565-570
Microvasculature of the Sheep Thymus....Pages 571-575
Tissue Localization and Migration of Murine Spleen Macrophages Carrying the Forssman Glycosphingolipid Antigen....Pages 577-582
Migration Patterns of Dendritic cells in the Mouse....Pages 583-589
A Monoclonal Antibody which Reacts Specifically with a Population of Bovine Lymphocytes Lacking B cell and T cell Markers....Pages 591-596
Meckel’s Diverticle: A Gut Associated Lymphoid Organ in Chickens....Pages 599-605
Subpopulations of Non-Lymphoid Cells in Bronchus Associated Lymphoid Tissue and Lung of the Mouse....Pages 607-613
Migration and Lodging of Peyer’s Patch IgA Precursor Cells in the Gut Lamina Propria....Pages 615-619
Localization, Isolation and Histochemical Characterization of Macrophages in the Gut and Mesenteric Lymph Nodes of the Rat....Pages 621-626
Direct Transdiaphragmatic Traffic of Peritoneal Macrophages to the Lung....Pages 627-632
Quantification and Class Distribution of Immunoglobulin-Secreting Cells in Mucosal Tissues of the Chicken....Pages 633-639
The Identification of Murine Peyer’s Patch T Cell-Derived Factors which Enhance IgA Responses....Pages 641-647
Role of the Galt Contrasuppressor T Cell Circuit in Isotype-Specific Immunoregulation....Pages 649-653
Evidence for Contrasuppression in Patients with Crohn’s Disease....Pages 655-663
Activated Fc Alpha T Cells in Crohn’s Disease are Involved in Regulation of IgA....Pages 665-673
Front Matter....Pages 43-43
Induction of a Combined Mucosal and Systemic Anti-Ovalbumin Response....Pages 675-680
Differential Expression of Epithelial MHC Class II Determinants (HLA-DR, -DP, and -DQ) and Increased Class I Expression in Inflamed Salivary Glands....Pages 681-688
Jejunal Epithelium of Patients with Coeliac Disease Shows Enhanced Expression of MHC Class II Subregion Products....Pages 689-693
T Cells and Epithelial Expression of HLA Class II Determinants in Relation to Putative M Cells of Follicle-Associated Epithelium in Human Peyer’s Patches....Pages 695-698
Modulation of Histamine Secretion from Rat and Human Mast Cell Subpopulations....Pages 699-704
Bacterial Characteristics and Follicle Surface Structure: Their Roles in Peyer’s Patch Uptake and Transport of Vibrio cholerae ....Pages 705-715
Mucosal Priming Alters Pathogenesis of Rift Valley Fever....Pages 717-723
J Chain is Expressed by More IgA2-than IgA1-Producing Cells in Colonic Mucosa, but it is Reduced in Both Subclasses in Inflammatory Bowel Disease....Pages 725-728
Ontogeny of Macrophages and Dendritic Cells of the Rat....Pages 731-736
Postnatal Development of Non-Lymphoid and Lymphoid Cell Populations in Situ in Diabetes-Prone BB Rats....Pages 737-743
Immunological Characteristics of Milky Spots in the Omentum of Rats....Pages 745-750
Lymphoid Dendritic Cells in Rheumatoid Tissue and Normal Blood — Characteristics and Functions....Pages 751-755
Interdigitating Cells and Dendritic Cells of the Mouse Identified by Monoclonal Antibodies: Interaction with Lymphocyte Subsets....Pages 757-763
Phenotypic Changes in Cultured Rat Dendritic Cells: Expression of IL-2 Receptor, Thy-1 and Other Antigens....Pages 765-769
Lymph Node Macrophage Heterogeneity: A Subpopulation Fails to Express Activation Phenotype....Pages 771-776
Induction of the Expression of an FcR for Monomeric Rat IgG2b on Rat Peritoneal Macrophages....Pages 777-781
Activation of Mononuclear Phagocyte Functions by Structurally Different Bacterial Endotoxins....Pages 783-787
Expression and Function of MHC Class II Antigens on Macrophages and Dendritic Cells....Pages 789-793
Induction of Class II MHC Antigen Expression in Rat Organs after Systemic Application of Recombinant Gamma Interferon....Pages 795-799
Human Peritoneal Macrophages Enhance HLA-DR Expression in Culture and are Very Potent Stimulators of an Allogeneic Mixed Leucocyte Reaction....Pages 801-806
Front Matter....Pages 43-43
The Effects of Bacterial Lipopolysaccharide (LPS) on High Endothelial Venules, T Lymphocytes and Interdigitating Cells in Mouse Lymph Nodes....Pages 807-811
Intestinal Uptake of Carrageenan: Distribution and Effects on Humoral Immune Competence....Pages 813-820
Carrageenan Induced Changes in the Immunomodulatory Capacity of Macrophages: An in Vitro Study....Pages 821-832
Immunoregulation in Epidermis: Glucocorticoids Induced Epidermal Cell Derived Inhibitor of Interleukin 1 Activity....Pages 833-837
Monocyte Defect Causes Decreased Automlr in Multiple Sclerosis Patients....Pages 839-842
Morphological Studies on Mitogen and Antigen Presentation by Human and Rabbit Cells....Pages 843-848
Physical Interaction Between Dendritic Cells and Lymphocytes is not LFA-1 Mediated....Pages 849-854
The Involvement of T-Cells in the Stimulatory Effect of a Water-in-Oil Emulsion on the B-Cell Response....Pages 855-860
Impact of IgD Receptor-Positive T Cells on the Immune Response....Pages 861-870
Spectrotype Modulation of BALB/C Anti (1-3>) Dextran 1355S Responses....Pages 871-875
B Lymphoma Cells Process and Present their Endogenous Ig: Implications for Network Theory....Pages 877-882
Germinal Center B Cells Present Antigen Obtained in vivo to T Cells in vitro and Stimulate Mixed Lymphocyte Reactions....Pages 883-888
Characterization of Cell Populations, Reappearing in the Mouse Spleen After Elimination by Liposome Encapsulated Dichloromethylene Diphosphonate: Reappearance of Marginal Zone Lymphocytes is Independent of Marginal Zone Macrophages....Pages 889-893
Localization of TI2 Antigen (Ficoll-FITC) and Corresponding Specific Anti-FITC Antibody Forming Cells in the Rat Spleen....Pages 895-899
In Vitro Infection of Human Epidermal Langerhans Cells with HIV....Pages 901-905
Accessory Cell Neoplasia as a Result of the Breakdown of Immunological Regulation?....Pages 907-912
Back Matter....Pages 913-916