High-throughput synthesis: principles and practices

 Content: An introduction to solid phase organic synthesis / Irving Sucholeiki --
 Methods of analysis to determine the progress of a chemical reaction on solid support / J. Manuel Perez --
 High-throughput organic synthesis: a perspective looking back on 10 years of combinatorial chemistry / Michael R. Pavia --
 Techniques and strategies for producing compound libraries for biological screening / Stephen R. Wilson, Kathryn Reinhard --
 Case study 4-1. A [gamma]-turn mimetic library: development and production / Petr Kocis ... [et al.] --
 Case study 4-2. Production of an [alpha]-ketoamide-containing library via convergent parallel synthesis / Alan P. Kaplan, Carmen M. Baldino --
 Case study 4-3. Manual solid phase synthesis of a fully encoded, 46,656-member benzimidazole library / David Tumelty ... [et al.] --
 Case study 4-4. Protease substrate specificity mapping using membrane-bound peptides / Richard A. Laursen, Caizhi Zhu, Yongjun Duan --
 Case study 4-5. Characterization of the epitope specificity of antibodies using membrane-bound peptides / Richard A. Laursen, Zhengxin Wang --
 Case study 4-6. Rapid parallel synthesis utilizing microwave irradiation / Brian M. Glass, Andrew P. Combs --
 High-throughput purification strategies / Mark J. Suto --
 Case study 5-1. Fluorous scavenging / Bruno Linclau. Dennis P. Curran --
 Case study 5-2. Polymer-assisted solution phase synthesis of [alpha]-ketoamides / John J. Parlow, Thomas A. Dice, Michael S. South --
 Case study 5-3. Ion exchange resins for the preparation of amide libraries / Mark J. Suto --
 Automating high-throughput organic synthesis / Paul D. Hoeprich, Jr. --
 Case study 6-1. Automated robotic parallel synthesis of a small-molecule library using multistep reactions on solid support / Surendrakumar Chaturvedi ... [et al.] --
 Case study 6-2. Solid-phase parallel synthesis of large tetrahydroisoquinolinone library / Michal Lebl ... [et al.] --
 Case study 6-3. Solid-phase parallel synthesis of a large array of tetrahydroisoquinolinones / Michal Lebl, Jaylynn C. Pires --
 Case study 6-4. High-output solid-phase synthesis of discrete compounds using directed split-and-pool strategy / Rongshi Li, Xiao-Yi Xiao, K.C. Nicolaou --
 Case study 6-5. Multistep synthesis of 1,2,3-thiadiazoles using "catch and release" / Yonghan Hu, Sylvie Baudart, John A. Porco, Jr. --
 Case study 6-6. Automated multistep solution phase synthesis of diamines and allylic amines / Fariba Aria --
 Synthesis and high-throughput evaluation of complex functional materials chips / Xiao-Dong Xiang --
 Case study 7-1. Studies of ferroelectric/dielectric materials using combinatorial materials chips / Hauyee Chang, Xiao-Dong Xiang --
 Case study 7-2. Synthesis and evaluation of thin-film dielectrics using a composition spread approach / R. Bruce van Dover, Lynn F. Schneemeyer --
 High-throughput screening of catalyst libraries / Richard C. Willson, David R. Hill, Phillip R. Gibbs --
 Case study 8-1. High-throughput screening of titanium-tripeptide Schiff base complexes for catalytic asymmetrical addition of trimethylsilylcyanide to epoxides and imines / Kevin W. Kuntz, Marc L. Snapper, Amir H. Hoveyda --
 Case study 8-2. Selection of effective polymer-bound acyl transfer catalysts by infrared thermography / James P. Morken, Steven J. Taylor --
 Microfluidic analysis, screening, and synthesis / C. Nicholas Hodge, Luc Bousse, Michael R. Knapp --
 Sensors / David R. Walt --
 Use of magnetic separation coupled with power ultrasound for high-throughput solid-phase organic synthesis / Irving Sucholeiki, J. Manuel Perez, Patrick D. Owens.