High Altitude Physiology and Medicine

Front Matter....Pages i-xx
Front Matter....Pages 1-1
Sleep Hypoxemia at Altitude....Pages 3-8
O 2 Breathing at Altitude: Effects on Maximal Performance....Pages 9-15
Oxygen Uptake at High Altitude: Limiting Role of Diffusion in Lungs....Pages 16-20
Respiratory and Cardiocirculatory Responses of Acclimatization of High Altitude Natives (La Paz, 3500 m) to Tropical Lowland (Santa Cruz, 420 m)....Pages 21-27
Chemoreflexive Ventilatory Response at Sea Level in Subjects With Past History of Good Acclimatization and Severe Acute Mountain Sickness....Pages 28-32
Dysoxia (Abnormal Cell O 2 Metabolism) and High Altitude Exposure....Pages 33-41
Minimal $${{\text{P}}_{{O_2}}}$$ in Working and Resting Tissues....Pages 45-53
Effects of High Altitude (Low Arterial $${{\text{P}}_{{O_2}}}$$ ) and of Displacements of the Oxygen Dissociation Curve of Blood on Peripheral O 2 Extraction and $${{\text{P}}_{{O_2}}}$$ ....Pages 54-65
Influence of the Position of the Oxygen Dissociation Curve on the Oxygen Supply to Tissues....Pages 66-72
Carbon Dioxide and Oxygen Dissociation Curves During and After a Stay at Moderate Altitude....Pages 73-77
Ventilatory, Circulatory, and Metabolic Mechanisms During Muscular Exercise at High Altitude (La Paz, 3500 m)....Pages 81-87
The Effects of Hypoxia on Maximal Anaerobic Alactic Power in Man....Pages 88-93
Anaerobic Metabolism at High Altitude: The Lactacid Mechanism....Pages 94-102
Oxygen Deficit and Debt in Submaximal Exercise at Sea Level and High Altitude....Pages 103-106
Blood Rheology in Hemoconcentration....Pages 109-116
Oxygen Transport Capacity....Pages 117-122
Skeletal Muscle Perfusion, Exercise Capacity, and the Optimal Hematocrit....Pages 123-128
Cardiac Output and Regional Blood Flows in Altitude Residents....Pages 129-141
The Pulmonary Circulation of High Altitude Natives....Pages 142-149
Comparison Between Newcomer Rats and First Generation of Rats Born at High Altitude, Particularly Concerning the Oxygen Supply to the Heart....Pages 150-155
Front Matter....Pages 1-1
Circulatory Flow of Oxygen Returning to the Lung During Submaximal Exercise in Altitude Residents....Pages 156-157
Effect of the α-Adrenergic Blocking Agent Phentolamine (Regitine) on Acute Hypoxic Pulmonary Hypertension in Awake Dogs....Pages 158-162
Hormonal Responses to Exercise at Altitude in Sea Level and Mountain Man....Pages 165-171
Time Course of Plasma Growth Hormone During Exercise in Man at Altitude....Pages 172-175
Transcapillary Escape Rate of Albumin After Exposure to 4300 m....Pages 176-178
Platelet Survival and Sequestration in the Lung at Altitude....Pages 179-182
Electrolyte Changes in the Blood and Urine of High Altitude Climbers....Pages 183-186
The Influence of Trekking on Some Hematologic Parameters and Urine Production....Pages 187-189
Front Matter....Pages 191-191
High Altitude Complaints, Diseases, and Accidents in Himalayan High Altitude Expeditions (1946–1978)....Pages 193-198
Cerebral Edema: The Influence of Hypoxia and Impaired Microcirculation....Pages 199-208
Physiologic Adaptation to Altitude and Hyperexis....Pages 209-211
Eye Problems at High Altitudes....Pages 212-214
Cotton-Wool Spots: A New Addition to High Altitude Retinopathy....Pages 215-216
High Altitude Pulmonary Edema: Analysis of 166 Cases....Pages 219-231
Hemodynamic Study of High Altitude Pulmonary Edema (12,200 ft)....Pages 232-241
Pathogenesis of High Altitude Pulmonary Edema (HAPE)....Pages 242-247
Subclinical Pulmonary Edema with Hypobaric Hypoxia....Pages 248-254
Mechanism of Pulmonary Edema Following Uneven Pulmonary Artery Obstruction and Its Relationship to High Altitude Lung Injury....Pages 255-260
Vasopressin in Acute Mountain Sickness and High Altitude Pulmonary Edema....Pages 261-262
Hypoxic Pulmonary Vasoconstriction and Ambient Temperature....Pages 263-265
Front Matter....Pages 191-191
Pathophysiology of Acute Mountain Sickness and High Altitude Pulmonary Edema: An Hypothesis....Pages 266-267
Use of Furosemide in Prevention of HAPE....Pages 268-268
Chronic Mountain Sickness: A Pulmonary Vascular Disease?....Pages 271-277
Predicting Mountaineering Performance at Great Altitudes....Pages 278-283
Effect of Ambient Temperature, Age, Sex, and Drugs on Survival Rate of Rats....Pages 284-287
Hemodilution: Practical Experiences in High Altitude Expeditions....Pages 291-297
How to Stay Healthy While Climbing Mount Everest....Pages 298-300
Proposals for International Standardization in the Research and Documentation of High Altitude Medicine....Pages 301-306
Equipment Requirements for High-Altitude Studies (Personal Experiences)....Pages 307-309
Back Matter....Pages 310-316