Handbook of Toxicology of Chemical Warfare Agents, Second Edition

Content: 
Front-matter, Pages i-iii
Copyright, Page iv
Dedication, Page v
List of Contributors, Pages xi-xiv
Chapter 1 - Introduction, Pages 3-5
Chapter 2 - Historical Perspective of Chemical Warfare Agents, Pages 7-15
Chapter 3 - Global Impact of Chemical Warfare Agents Used Before and After 1945, Pages 17-25
Chapter 4 - The Tokyo Subway Sarin Attack: Acute and Delayed Health Effects in Survivors, Pages 27-35
Chapter 5 - Early and Delayed Effects of Sulfur Mustard in Iranian Veterans After the Iraq–Iran Conflict, Pages 37-46
Chapter 6 - Epidemiology of Chemical Warfare Agents, Pages 47-54
Chapter 7 - Chemical Weapons of Mass Destruction and Terrorism: A Threat Analysis, Pages 55-65
Chapter 8 - Mustards and Vesicants, Pages 69-86
Chapter 9 - Organophosphate Nerve Agents, Pages 87-109
Chapter 10 - Russian VX, Pages 111-130
Chapter 11 - Riot Control Agents, Pages 131-150
Chapter 12 - Psychotomimetic Agent BZ (3-Quinuclidinyl Benzilate), Pages 151-157
Chapter 13 - Neurological Effects and Mechanisms of Blast Overpressure Injury, Pages 159-166
Chapter 14 - Thallium, Pages 167-170
Chapter 15 - Arsenicals: Toxicity, Their Use as Chemical Warfare Agents, and Possible Remedial Measures, Pages 171-191
Chapter 16 - Fluoroacetate, Pages 193-214
Chapter 17 - Strychnine, Pages 215-222
Chapter 18 - Superwarfarins, Pages 223-238
Chapter 19 - PCBs, Dioxins and Furans: Human Exposure and Health Effects, Pages 239-247
Chapter 20 - Polycyclic Aromatic Hydrocarbons: Implications for Developmental, Molecular, and Behavioral Neurotoxicity, Pages 249-265
Chapter 21 - Carbon Monoxide: From Public Health Risk to Painless Killer, Pages 267-286
Chapter 22 - Methyl Isocyanate: The Bhopal Gas, Pages 287-299
Chapter 23 - Cyanide Toxicity and its Treatment, Pages 301-314
Chapter 24 - Chlorine, Pages 315-325
Chapter 25 - Phosgene, Pages 327-335
Chapter 26 - Other Toxic Chemicals as Potential Chemical Warfare Agents, Pages 337-345
Chapter 27 - Ricin, Pages 347-360
Chapter 28 - Botulinum Toxin*, Pages 361-385
Chapter 29 - Anthrax, Pages 387-410
Chapter 30 - Onchidal and Fasciculins, Pages 411-420
Chapter 31 - Cyanobacterial (Blue-Green Algae) Toxins, Pages 421-429
Chapter 32 - Radiation and Health Effects, Pages 431-446
Chapter 33 - Depleted Uranium, Pages 447-460
Chapter 34 - Chemical Warfare Agents and the Nervous System, Pages 463-475
Chapter 35 - Behavioral Toxicity of Nerve Agents, Pages 477-487
Chapter 36 - The Respiratory Toxicity of Chemical Warfare Agents, Pages 489-518
Chapter 37 - Cardiovascular System as a Target of Chemical Warfare Agents, Pages 519-533
Chapter 38 - Ocular Toxicity of Chemical Warfare Agents, Pages 535-555
Chapter 39 - Dermal Toxicity of Sulfur Mustard, Pages 557-576
Chapter 40 - Skeletal Muscle, Pages 577-597
Chapter 41 - Reproductive Toxicity and Endocrine Disruption of Potential Chemical Warfare Agents, Pages 599-613
Chapter 42 - Liver Toxicity of Chemical Warfare Agents, Pages 615-626
Chapter 43 - Renal System, Pages 627-637
Chapter 44 - The Immune System as a Target for Chemical Warfare Agents, Pages 639-655
Chapter 45 - Alternative Animal Toxicity Testing of Chemical Warfare Agents, Pages 657-673
Chapter 46 - Genomics and Proteomics in Brain Complexity in Relation to Chemically Induced PTSD, Pages 677-689
Chapter 47 - Clinical and Cellular Aspects of Traumatic Brain Injury, Pages 691-708
Chapter 48 - Excitotoxicity, Oxidative Stress, and Neuronal Injury, Pages 709-724
Chapter 49 - Blood–Brain Barrier Damage and Dysfunction by Chemical Toxicity, Pages 725-739
Chapter 50 - Neuropathologic Effects of Chemical Warfare Agents, Pages 741-749
Chapter 51 - The Effects of Organophosphates in the Early Stages of Human Muscle Regeneration, Pages 751-759
Chapter 52 - Cholinesterase Inhibitors: From Molecular Mechanisms of Action to Current and Future Prospects, Pages 761-778
Chapter 53 - Potential Agents That Can Cause Contamination of Animal Feedstuffs and Terror, Pages 781-790
Chapter 54 - Chemical Warfare Agents and Risks to Animal Health, Pages 791-807
Chapter 55 - Threats to Wildlife by Chemical and Warfare Agents, Pages 809-814
Chapter 56 - Toxicokinetic Aspects of Nerve Agents and Vesicants, Pages 817-856
Chapter 57 - Toxicokinetics and Toxicodynamics of DFP, Pages 857-874
Chapter 58 - Physiologically Based Pharmacokinetic Modeling of Chemical Warfare Agents, Pages 875-882
Chapter 59 - Biotransformation of Warfare Nerve Agents, Pages 883-894
Chapter 60 - On-Site Detection of Chemical Warfare Agents, Pages 897-914
Chapter 61 - Laboratory Analysis of Chemical Warfare Agents, Adducts, and Metabolites in Biomedical Samples, Pages 915-923
Chapter 62 - Biosensors for the Detection of OP Nerve Agents, Pages 925-934
Chapter 63 - Neuropathy Target Esterase as a Biomarker and Biosensor of Delayed Neuropathic Agents, Pages 935-952
Chapter 64 - Biomarkers of Exposure to Organophosphorus Poisons: A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine, Pages 953-965
Chapter 65 - Monitoring of Blood Cholinesterase Activity in Workers Exposed to Nerve Agents, Pages 967-976
Chapter 66 - Pharmacological Prophylaxis Against Nerve Agent Poisoning: Experimental Studies and Practical Implications, Pages 979-987
Chapter 67 - Prophylactic and Therapeutic Measures in Nerve Agents Poisoning, Pages 989-1001
Chapter 68 - Medical Management of Chemical Toxicity in Pediatrics, Pages 1003-1034
Chapter 69 - Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling of Countermeasures to Nerve Agents, Pages 1035-1047
Chapter 70 - Strategies to Enhance Medical Countermeasures After the Use of Chemical Warfare Agents on Civilians, Pages 1049-1056
Chapter 71 - Pyridinium Oximes in the Treatment of Poisoning with Organophosphorus Compounds, Pages 1057-1070
Chapter 72 - Novel Cholinesterase Reactivators, Pages 1071-1087
Chapter 73 - Paraoxonase (PON1) and Detoxication of Nerve Agents, Pages 1089-1098
Chapter 74 - The Role of Carboxylesterases in Therapeutic Intervention of Nerve Gases Poisoning, Pages 1099-1106
Chapter 75 - Catalytic Bioscavengers: The New Generation of Bioscavenger-Based Medical Countermeasures, Pages 1107-1123
Chapter 76 - Rapid Decontamination of Chemical Warfare Agents from the Skin, Pages 1127-1139
Index, Pages 1141-1184