Handbook of Statistical Bioinformatics

Front Matter....Pages i-ix
Front Matter....Pages 1-1
Accuracy Assessment of Consensus Sequence from Shotgun Sequencing....Pages 3-30
Statistical and Computational Studies on Alternative Splicing....Pages 31-53
Statistical Learning and Modeling of TF-DNA Binding....Pages 55-72
Computational Promoter Prediction in a Vertebrate Genome....Pages 73-85
Discovering Influential Variables: A General Computer Intensive Method for Common Genetic Disorders....Pages 87-107
STORMSeq: A Method for Ranking Regulatory Sequences by Integrating Experimental Datasets with Diverse Computational Predictions....Pages 109-134
Mixture Tree Construction and Its Applications....Pages 135-147
Front Matter....Pages 149-149
Experimental Designs and ANOVA for Microarray Data....Pages 151-169
The MicroArray Quality Control (MAQC) Project and Cross-Platform Analysis of Microarray Data....Pages 171-192
A Survey of Classification Techniques for Microarray Data Analysis....Pages 193-223
Statistical Analysis of Single Nucleotide Polymorphism Microarrays in Cancer Studies....Pages 225-255
Computational Analysis of ChIP-chip Data....Pages 257-282
eQTL Mapping for Functional Classes of Saccharomyces cerevisiae Genes with Multivariate Sparse Partial Least Squares Regression....Pages 283-298
Statistical Analysis of Time Course Microarray Data....Pages 299-313
Front Matter....Pages 315-315
Kernel Methods in Bioinformatics....Pages 317-334
Graph Classification Methods in Chemoinformatics....Pages 335-351
Hidden Markov Random Field Models for Network-Based Analysis of Genomic Data....Pages 353-368
Review of Weighted Gene Coexpression Network Analysis....Pages 369-388
Liquid Association and Related Ideas in Quantifying Changes in Correlation....Pages 389-404
Boolean Networks....Pages 405-425
Front Matter....Pages 315-315
Protein Interaction Networks: Protein Domain Interaction and Protein Function Prediction....Pages 427-459
Reverse Engineering of Gene Regulation Networks with an Application to the DREAM4 in silico Network Challenge....Pages 461-477
Inferring Signaling and Gene Regulatory Network from Genetic and Genomic Information....Pages 479-500
Computational Drug Target Pathway Discovery: A Bayesian Network Approach....Pages 501-532
Cancer Systems Biology....Pages 533-565
Comparative Genomics....Pages 567-600
Robust Control of Immune Systems Under Noises: Stochastic Game Approach....Pages 601-627