Handbook of Mutagenicity Test Procedures

Content: 
Front Matter, Page iii
Copyright, Page iv
PREFACE TO THE FIRST EDITION, Pages v-vi, BRIAN KILBEY
PREFACE TO THE SECOND EDITION, Page vii, B.J. KILBEY
LIST OF CONTRIBUTORS, Pages xiii-xvi
1 - NEWER METHODS FOR DETERMINING GENOTOXICITY USING DNA REPAIR-DEFICIENT AND REPAIR-PROFICIENT ESCHERICHIA COLI, Pages 1-11, Herbert S. Rosenkranz
2 - BACILLUS SUBTILIS REPAIR TEST, Pages 13-31, T. Kada, Y. Sadaie, Y. Sakamoto
3 - METHODS FOR STUDYING EXCISION REPAIR OF EUKARYOTIC DNA DAMAGED BY PHYSICAL AND CHEMICAL MUTAGENS, Pages 33-69, James E. Cleaver
4 - METHODS FOR DETECTING CARCINOGENS AND MUTAGENS WITH THE ALKALINE ELUTION/RAT HEPATOCYTE ASSAY, Pages 71-82, Matthews O. Bradley, Joseph F. Sina
5 - INDUCED REVERSION USING HUMAN ADENOVIRUS, Pages 83-91, Rufus S. Day III, Chuck H.J. Ziolkowski
6 - REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST, Pages 93-140, Dorothy M. Maron, Bruce N. Ames
7 - THE FLUCTUATION TEST IN BACTERIA, Pages 141-160, S.A. Hubbard, M.H.L. Green, D. Gatehouse, J.W. Bridges
8 - MUTAGEN TESTING USING Trp+ REVERSION IN ESCHERICHIA COLI, Pages 161-187, M.H.L. Green
9 - METHODOLOGIES FOR THE DIRECT AND ANIMAL-MEDIATED DETERMINATION OF VARIOUS GENETIC EFFECTS IN DERIVATIVES OF STRAIN 343/113 OF ESCHERICHIA COLI K-12, Pages 189-214, G. Mohn, P. Kerklaan, J. Ellenberger
10 - BASIC PRINCIPLES AND METHODS OF GENOTOXICITY TESTING IN THE YEAST SACCHAROMYCES CEREVISIAE, Pages 215-238, Friedrich K. Zimmermann
11 - PROCEDURES FOR THE L5178Y/TK+/− → TK−/− MOUSE LYMPHOMA CELL MUTAGENICITY ASSAY, Pages 239-268, Nancy T. Turner, A. Gail Batson, Donald Clive
12 - A QUANTITATIVE TEST FOR MUTAGENICITY IN V79 CHINESE HAMSTER CELLS, Pages 269-290, Dag Jenssen
13 - GENETIC MARKERS FOR QUANTITATIVE MUTAGENESIS STUDIES IN CHINESE HAMSTER OVARY CELLS: APPLICATIONS TO MUTAGEN SCREENING STUDIES, Pages 291-319, Radhey S. Gupta
14 - CHEMICAL MUTAGENESIS WITH DIPLOID HUMAN FIBROBLASTS, Pages 321-356, Lois Jacobs, Robert DeMars
15 - 6-THIOGUANINE-RESISTANT LYMPHOCYTES IN HUMAN BLOOD, Pages 357-372, Richard J. Albertini, David L. Sylwester
16 - THE SPECIFIC LOCUS TEST IN THE MOUSE, Pages 373-391, A.G. Searle
17 - PROCEDURES AND EVALUATION OF RESULTS OF THE MOUSE SPOT TEST, Pages 393-403, Liane B. Russell
18 - HUMAN PERIPHERAL BLOOD LYMPHOCYTES FOR THE ANALYSIS OF CHROMOSOME ABERRATIONS IN MUTAGEN TESTS, Pages 405-427, H.J. Evans
19 - IN VITRO ANAPHASE AND METAPHASE PREPARATIONS IN MUTATION TESTING, Pages 429-439, Warren W. Nichols, Robert C. Miller, Carole I. Bradt
20 - THE BONE MARROW MICRONUCLEUS TEST, Pages 441-457, John A. Heddle, Earl Stuart, Michael F. Salamone
21 - CYTOGENETIC ANALYSIS OF STRUCTURAL CHROMOSOME ABERRATIONS AND ANEUPLOIDIES IN OOCYTES, ZYGOTES AND PREIMPLANTATION EMBRYOS OF MAMMALS, Pages 459-470, G. Röhrborn, A. Basler
22 - THE DOMINANT LETHAL ASSAY IN THE MALE MOUSE, Pages 471-483, A.J. Bateman
23 - TEST FOR HERITABLE TRANSLOCATIONS IN MALE MAMMALS, Pages 485-494, A. Léonard, I.D. Adler
24 - THE METHODOLOGY OF SISTER CHROMATID EXCHANGES, Pages 495-529, Paul E. Perry, Eric J. Thomson
25 - ROOT TIPS OF VICIA FABA FOR THE STUDY OF THE INDUCTION OF CHROMOSOMAL ABERRATIONS AND SISTER CHROMATID EXCHANGES, Pages 531-554, B.A. Kihlman, H.C. Andersson
26 - DROSOPHILA AS AN ASSAY SYSTEM FOR DETECTING GENETIC CHANGES, Pages 555-601, F.E. Würgler, F.H. Sobels, E. Vogel
27 - EYE PIGMENTATION CHANGES IN DROSOPHILA MELANOGASTER AS A SENSITIVE TEST FOR MUTAGENICITY, Pages 603-613, Bertil Rasmuson, Åsa Rasmuson, Jan Nygren
28 - METABOLIC ACTIVATION SYSTEMS IN SHORT-TERM IN VITRO TESTS, Pages 615-641, Christian Malaveille, Helmut Bartsch
29 - THE INTRAPERITONEAL HOST-MEDIATED ASSAY, Pages 643-654, Thomas H. Connor, Marvin S. Legator
30 - THE ISOLATED PERFUSED LIVER AS A METABOLIZING SYSTEM IN MUTAGENICITY TESTING, Pages 655-688, Brita Beije
31 - THE DETECTION OF INDUCED CHROMOSOME ANEUPLOIDY USING STRAINS OF THE YEAST SACCHAROMYCES CEREVISIAE, Pages 689-706, James M. Parry, Elizabeth M. Parry
32 - METHODS FOR DETECTING THE INDUCTION OF MITOTIC CHROMOSOMAL MIS-DISTRIBUTION IN ASPERGILLUS NIDULANS, Pages 707-720, Giampiero Gualandi, Giorgio Morpurgo
33 - SYSTEMS FOR DETECTING MEIOTIC ANEUPLOIDY IN SORDARIA AND NEUROSPORA, Pages 721-737, D.J. Bond
34 - SPERM MORPHOLOGY TESTING IN MICE, Pages 739-750, A.J. Wyrobek, G. Watchmaker, L. Gordon
35 - SAFETY PRECAUTIONS IN WORK WITH MUTAGENIC AND CARCINOGENIC CHEMICALS, Pages 751-763, Lars Ehrenberg, Carl Axel Wachtmeister
36 - HANDLING OF MUTAGENIC CHEMICALS: EXPERIMENTAL SAFETY, Pages 765-774, Lars Ehrenberg, Carl Axel Wachtmeister
37 - ASPECTS OF STATISTICAL INFERENCE IN TESTING FOR GENETIC TOXICITY, Pages 775-822, Lars Ehrenberg
38 - PREVENTION, DETECTION AND CONTROL OF MYCOPLASMAL INFECTION OF CELL CULTURES, Pages 823-839, Gerard J. McGarrity, Theodor Steiner, Lindsay Gamon
39 - MUTATION EPIDEMIOLOGY AND ITS PROSPECTS FOR DETECTING HUMAN GERMINAL MUTAGENS, Pages 841-851, John J. Mulvihill, James R. Miller
INDEX, Pages 853-859