Handbook of drug monitoring methods : therapeutics and drugs of abuse

Front Matter....Pages I-X
Introduction to Therapeutic Drug Monitoring....Pages 1-39
Monitoring Free Drug Concentration....Pages 41-65
Analytical Techniques for Measuring Concentrations of Therapeutic Drugs in Biological Fluids....Pages 67-86
The Pre-Analytical Phase of Drug Testing....Pages 87-96
Effect of Hemolysis, High Bilirubin, Lipemia, Paraproteins, and System Factors on Therapeutic Drug Monitoring....Pages 97-109
Digoxin....Pages 111-131
Interferences with Measurement of Anticonvulsants....Pages 133-148
Pitfalls in Measuring Antidepressant Drugs....Pages 148-163
Immunosuppressive Drugs....Pages 165-199
Therapeutic Drug Monitoring in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome....Pages 201-210
Pharmacogenomics and Personalized Medicine....Pages 211-223
Interference of Heterophilic and Other Antibodies in Measurement of Therapeutic Drugs by Immunoassays....Pages 225-233
Drug–Herb and Drug–Food Interactions....Pages 235-261
Toxic Element Testing with Clinical Specimens....Pages 263-282
Alcohol Testing....Pages 283-295
Introduction to Drugs of Abuse Testing....Pages 297-315
Urinary Adulterants and Drugs of Abuse Testing....Pages 317-335
Hair, Oral Fluid, Sweat, and Meconium Testing for Drugs of Abuse....Pages 337-364
Abused and Designer Drugs and How They Escape Detection....Pages 365-377
Interpretation of Amphetamines Screening and Confirmation Testing....Pages 379-393
Clinical False-Positive Drug Test Results....Pages 395-406
Providing Expert Witness for Alcohol and Positive Drugs of Abuse Test Results....Pages 407-420
Back Matter....Pages 421-445