Handbook of Anticancer Drugs from Marine Origin

Front Matter....Pages i-xvi
Introduction to Anticancer Drugs from Marine Origin....Pages 1-13
Triterpenoids as Anticancer Drugs from Marine Sponges....Pages 15-27
Marine Sponge Derived Antiangiogenic Compounds....Pages 29-58
Marine Sponge Derived Eribulin in Preclinical and Clinical Studies for Cancer....Pages 59-100
Antitumour Effect of Cyclodepsipeptides from Marine Sponges....Pages 101-111
Cytotoxic Cyclic Peptides from the Marine Sponges....Pages 113-144
Fucoidan, A Sulfated Polysaccharides from Brown Algae as Therapeutic Target for Cancer....Pages 145-164
Seaweeds-Derived Bioactive Materials for the Prevention and Treatment of Female’s Cancer....Pages 165-176
Antitumor and Antimetastatic Effects of Marine Algal Polyphenols....Pages 177-183
Seaweed Carotenoids for Cancer Therapeutics....Pages 185-203
Amelioration Effect of a Tertiary Sulfonium Compound, Dimethylsulfoniopropionate, in Green Sea Algae on Ehrlich Ascitic-tumor, Solid Tumor and Related Diseases....Pages 205-238
The Current Status of Novel Anticancer Drugs from Marine Actinobacteria....Pages 239-251
Natural Products with Anticancer Activity from Marine Fungi....Pages 253-267
Toluquinol, A Marine Fungus Metabolite, Inhibits Some of the Hallmarks of Cancer....Pages 269-299
Anticancer Diketopiperazines from the Marine Fungus....Pages 301-322
Meroterpenoids from Marine Microorganisms: Potential Scaffolds for New Chemotherapy Leads....Pages 323-366
Antitumor Compounds from Actinomycetes in Deep-sea Water of Toyama Bay....Pages 367-382
Tunicates: A Vertebrate Ancestral Source of Antitumor Compounds....Pages 383-395
Trabectedin (ET-743) from Marine Tunicate for Cancer Treatment....Pages 397-412
Anti-Cancer Effects of Chitin and Chitosan Derivatives....Pages 413-421
Meroterpenes from Marine Invertebrates: Chemistry and Application in Cancer....Pages 423-437
Marine Sponge Sesterpenoids as Potent Apoptosis-Inducing Factors in Human Carcinoma Cell Lines....Pages 439-479
Advances of Microtubule-Targeting Small Molecular Anticancer Agents from Marine Origin....Pages 481-513
Cytotoxic Triterpene Glycosides from Sea Cucumbers....Pages 515-528
Targeting Cellular Proapoptotic Agents from Marine Sources....Pages 529-545
Discovery and Computer-Aided Drug Design Studies of the Anticancer Marine Triterpene Sipholanes as Novel P-gp and Brk Modulators....Pages 547-569
Molecular Targets of Anticancer Agents from Filamentous Marine Cyanobacteria....Pages 571-592
P-gp Inhibitory Activity from Marine Sponges, Tunicates and Algae....Pages 593-619
Marine Cyanobacteria Compounds with Anticancer Properties: Implication of Apoptosis....Pages 621-647
Cytotoxic Cembrane Diterpenoids....Pages 649-672
Anti-cancer Effects of Triterpene Glycosides, Frondoside A and Cucumarioside A 2 -2 Isolated from Sea Cucumbers....Pages 673-682
Pederin, Psymberin and the Structurally Related Mycalamides: Synthetic Aspects and Biological Activities....Pages 683-700
Antitumor Effects of Sea Hare-Derived Compounds in Cancer....Pages 701-739
Marine Sponge Derived Actinomycetes and Their Anticancer Compounds....Pages 741-755
Cytotoxic Terpene-Purines and Terpene-Quinones from the Sea....Pages 757-769
Pyridoacridine Alkaloids from Marine Origin: Sources and Anticancer Activity....Pages 771-802
Back Matter....Pages 803-805