GTPases in Biology II

Front Matter....Pages I-XL
Front Matter....Pages 1-1
Molecular Diversity of Mammalian Adenylyl Cyclases: Functional Consequences....Pages 189-212
The Light-Regulated cGMP Phosphodiesterase of Vertebrate Photoreceptors: Structure and Mechanism of Activation by G tα ....Pages 213-223
High-Voltage Activated Ca 2+ Channel....Pages 225-238
Phospholipase C-β Isozymes Activated by Gα q Members....Pages 239-249
Stimulation of Phospholipase C by G-Protein βγ Subunits....Pages 251-264
Rhodopsin/G-Protein Interaction....Pages 267-290
Fast Kinetics of G-Protein Function In Vivo....Pages 291-302
The Yeast Pheromone Response G-Protein....Pages 303-318
Gα Proteins in Drosophila : Structure and Developmental Expression....Pages 319-334
G-Proteins Have Properties of Multimeric Proteins: An Explanation for the Role of GTPases in their Dynamic Behavior....Pages 3-14
The Superfamily: Molecular Modelling....Pages 17-31
The Role of Receptor Kinases and Arrestin-Like Proteins in G-Protein-Linked Receptor Desensitization....Pages 33-42
Qualitative and Quantitative Characterization of the Distribution of G-Protein α Subunits in Mammals....Pages 45-64
Subunit Interactions of Heterotrimeric G-Proteins....Pages 65-78
G-Protein α Subunit Chimeras Reveal Specific Regulatory Domains Encoded in the Primary Sequence....Pages 79-97
The GTPase Cycle: Transducin....Pages 99-117
Transcriptional, Posttranscriptional, and Posttranslational Regulation of G-Proteins and Adrenergic Receptors....Pages 119-130
G-Protein Subunit Lipidation in Membrane Association and Signaling....Pages 131-146
Phosphorylation of Heterotrimeric G-Protein....Pages 147-165
Receptor to Effector Signaling Through G-Proteins: βγ Dimers Join α Subunits in the World of Higher Eukaryotes....Pages 167-186
Front Matter....Pages 1-1
Signal Transduction by G-Proteins in Dictyostelium discoideum ....Pages 335-349
Functional Expression of Mammalian Receptors and G-Proteins in Yeast....Pages 351-362
G-Proteins in the Signal Transduction of the Neutrophil....Pages 363-373
Hormonal Regulation of Phospholipid Metabolism via G-Proteins: Phosphoinositide Phospholipase C and Phosphatidylcholine Phospholipase D....Pages 375-385
Hormonal Regulation of Phospholipid Metabolism via G-proteins II: PLA 2 and Inhibitory Regulation of PLC....Pages 387-400
G-Protein Regulation of Phospholipase C in the Turkey Erythrocyte....Pages 401-415
Hormonal Inhibition of Adenylyl Cyclase by α i and βγ, α i orβγ, α i and/or βγ....Pages 417-428
Neurobiology of G o ....Pages 429-446
Involvement of Pertussis-Toxin-Sensitive G-Proteins in the Modulation of Ca 2+ Channels by Hormones and Neurotransmitters....Pages 447-469
Regulation of Cell Growth and Proliferation by G o ....Pages 471-484
Role of Nucleoside Diphosphate Kinase in G-Protein Action....Pages 485-498
G-Protein Regulation of Cardiac K + Channels....Pages 499-526
Modulation of K + Channels by G-Proteins....Pages 527-546
ATP-Sensitive K + Channel: Properties, Occurrence, Role in Regulation of Insulin Secretion....Pages 547-559
Modulation of Maxi-Calcium-Activated K Channels: Role of Ligands, Phosphorylation, and G-Proteins....Pages 561-579
Regulation of the Endosomal Proton Translocating ATPase (H + -ATPase) and Endosomal Acidification by G-Proteins....Pages 581-596
cAMP-Independent Regulation of Adipocyte Glucose Transport Activity and Other Metabolic Processes by a Complex of Receptors and Their Associated G-Proteins....Pages 597-609
Back Matter....Pages 611-618